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Toxicity of Nanomaterials to the Host and the Environment

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Mucosal Delivery of Drugs and Biologics in Nanoparticles

Part of the book series: AAPS Advances in the Pharmaceutical Sciences Series ((AAPS,volume 41))

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Abstract

Although silver nanoparticles (AgNPs) display excellent antibacterial, antifungal, and antiviral properties; the pervasiveness of AgNPs in occupational, medicinal, consumer, and environmental settings has raised concerns about the potential for adverse health effects and environmental risks. We provide herein an overview of the use of AgNPs, routes of AgNPS exposure, physicochemical properties and mechanisms responsible for toxicity, and strategies to establish the safety of AgNPs. The core of this book chapter is the notion that while AgNPs may be effective agents in exterminating various pathogens, they may also damage healthy cells, animals, humans, and ecosystems. Thus, the manufacture and usage of AgNPs should be closely monitored and regulated.

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Authors and Affiliations

  1. Department of Biomedical and Pharmaceutical Sciences, Center for Biomolecular Structure and Dynamics, The University of Montana, Missoula, MT, USA

    Celine A. Beamer

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  1. Celine A. Beamer
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Correspondence to Celine A. Beamer .

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  1. Department of Pharmaceutical Sciences, College Pharmacy, University of New Mexico, Albuquerque, NM, USA

    Pavan Muttil

  2. Department of Pharmaceutical Sciences College of Pharmacy and Health Sciences, St. John’s University, Jamaica, NY, USA

    Nitesh K. Kunda

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Beamer, C.A. (2020). Toxicity of Nanomaterials to the Host and the Environment. In: Muttil, P., Kunda, N. (eds) Mucosal Delivery of Drugs and Biologics in Nanoparticles. AAPS Advances in the Pharmaceutical Sciences Series, vol 41. Springer, Cham. https://doi.org/10.1007/978-3-030-35910-2_10

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