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Introduction to Nanomedicine in Drug Delivery

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Book cover Mucosal Delivery of Drugs and Biologics in Nanoparticles

Part of the book series: AAPS Advances in the Pharmaceutical Sciences Series ((AAPS,volume 41))

Abstract

Recent advances in the field of nanotechnology have given a boost to the academic researchers, the pharmaceutical and biomedical industry, allowing its use in drug delivery and medical diagnosis. Nanotechnology allows the formulation of drug delivery carriers in the nanometer range that helps in overcoming disadvantages associated with conventional drug delivery systems by being small, target-specific, improved drug encapsulation, stable and less toxic at the same time. With nanotechnology, many drugs especially oncogenic molecules that are toxic or are difficult to deliver have been formulated and delivered successfully and are currently in the market, for example, Myocet® (2000) (Doxorubicin) and Marqibo® (2012) (Vincristine). Nanoparticle-based drug delivery carriers can be classified into two types; organic and inorganic. Organic nanoparticles are mostly used for drug delivery, while inorganic nanoparticles are majorly involved in diagnosis. Organic nanoparticles generally involve but are not limited to liposomes, dendrimers, polymeric micelles, polymeric nanoparticles, and solid lipid nanoparticles. Inorganic nanoparticles involve metals such as gold, silver, and iron oxide. In this chapter, we will discuss the advantages and disadvantages of nanoparticles and various materials that are used for making different types of nanoparticles with relevant examples. Further, we will discuss the recent developments in this field with some examples pertaining to each type of nanoparticles.

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Authors and Affiliations

  1. Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John’s University, Jamaica, NY, USA

    Tejashri Chavan & Nitesh K. Kunda

  2. Department of Pharmaceutical Sciences, College of Pharmacy, University of New Mexico, Albuquerque, NM, USA

    Pavan Muttil

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  1. Tejashri Chavan
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  2. Pavan Muttil
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Correspondence to Nitesh K. Kunda .

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  1. Department of Pharmaceutical Sciences, College Pharmacy, University of New Mexico, Albuquerque, NM, USA

    Pavan Muttil

  2. Department of Pharmaceutical Sciences College of Pharmacy and Health Sciences, St. John’s University, Jamaica, NY, USA

    Nitesh K. Kunda

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Chavan, T., Muttil, P., Kunda, N.K. (2020). Introduction to Nanomedicine in Drug Delivery. In: Muttil, P., Kunda, N. (eds) Mucosal Delivery of Drugs and Biologics in Nanoparticles. AAPS Advances in the Pharmaceutical Sciences Series, vol 41. Springer, Cham. https://doi.org/10.1007/978-3-030-35910-2_1

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