Abstract
Quality assessment of different Magnetic Resonance Fingerprinting (MRF) sequences and their corresponding dictionaries remains an unsolved problem. In this work we present a method in which we approach analysis of MRF dictionaries by performing dimensionality reduction and representing them as low-dimensional point sets (embeddings). Dimensionality reduction was performed using a modification of the t-Distributed Stochastic Neighbor Embedding (t-SNE) algorithm. First, we demonstrated stability of calculated embeddings that allows neglecting the stochastic nature of t-SNE. Next, we proposed and analyzed two algorithms for comparing the embeddings. Finally, we performed two simulations in which we reduced the MRF sequence/dictionary in length or size and analyzed the influence of this reduction on the resulting embedding. We believe that this research can pave the way to development of a software tool for analysis, including better understanding, optimization and comparison, of different MRF sequences.
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Dzyubachyk, O., Koolstra, K., Pezzotti, N., Lelieveldt, B.P.F., Webb, A., Börnert, P. (2019). Comparative Analysis of Magnetic Resonance Fingerprinting Dictionaries via Dimensionality Reduction. In: Zhang, D., Zhou, L., Jie, B., Liu, M. (eds) Graph Learning in Medical Imaging. GLMI 2019. Lecture Notes in Computer Science(), vol 11849. Springer, Cham. https://doi.org/10.1007/978-3-030-35817-4_6
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DOI: https://doi.org/10.1007/978-3-030-35817-4_6
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