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Challenges in the Design of Large-Scale, High-Density, Wireless Stimulation and Recording Interface

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Interfacing Bioelectronics and Biomedical Sensing

Abstract

The need to better understand the nervous system drives the technological advancements in the development of neural stimulation and recording interface. In spite of rapid technological evolution, there are still challenges to realize a large-scale, high-density neural interface. In this chapter, we first discuss the design challenges from the system to the components level for a high-density wireless stimulation and recording system. State-of-the-art technologies for the critical functional blocks in the system, including ultrahigh-data-rate wireless link, suppression of the stimulation artifact, focalized stimulation scheme, and high-density electrode array are also reviewed. At the end of this chapter, a large-scale, high-density wireless stimulation and recording system that integrates those critical components are presented.

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Acknowledgments

Seo, K. J. and Fang, H. acknowledge support of this work by the National Science Foundation (NSF CAREER, ECCS-1847215), the National Institutes of Health (NIH R21EY030710) and the Samsung Global Research Outreach (GRO) program.

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Authors and Affiliations

  1. Department of Bioengineering, University of California, Los Angeles, Los Angeles, CA, USA

    Po-Min Wang, Stanislav Culaclii, Yushan Wang & Wentai Liu

  2. Department of Electrical and Computer Engineering, Northeastern University, Boston, MA, USA

    Kyung Jin Seo & Hui Fang

  3. Niche Biomedical Inc., Los Angeles, CA, USA

    Yi-Kai Lo

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  1. Po-Min Wang
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  2. Stanislav Culaclii
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  6. Yi-Kai Lo
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  7. Wentai Liu
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Correspondence to Wentai Liu .

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Editors and Affiliations

  1. Electrical Engineering and Computer Science, University of California, Irvine, Irvine, CA, USA

    Hung Cao

  2. Department of Bioengineering, University of California, San Diego, La Jolla, CA, USA

    Todd Coleman

  3. Department of Bioengineering, University of California Los Angeles, Los Angeles, CA, USA

    Tzung K. Hsiai

  4. California NanoSystems Institute, University of California Los Angeles, Los Angeles, CA, USA

    Ali Khademhosseini

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Wang, PM. et al. (2020). Challenges in the Design of Large-Scale, High-Density, Wireless Stimulation and Recording Interface. In: Cao, H., Coleman, T., Hsiai, T., Khademhosseini, A. (eds) Interfacing Bioelectronics and Biomedical Sensing. Springer, Cham. https://doi.org/10.1007/978-3-030-34467-2_1

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