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Endocrine and Metabolic Consequences of Turner Syndrome

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Abstract

Numerous important advances have been noted during recent years. These advances cover all specialty fields involved in the care of girls and women with TS, including (1) diagnostic and genetic issues, (2) growth and development during childhood and adolescence, (3) congenital and acquired cardiovascular disease, (4) transition and adult care, and (5) other comorbidities and neurocognitive issues. Here, we will present the most important new advances concerning endocrine and metabolic care of Turner syndrome.

Osteoporosis, diabetes, both type 1 and 2, hypothyroidism, obesity, and a host of other endocrinological diseases and conditions are seen more frequently in Turner syndrome in the long term. Other autoimmune diseases, such as celiac disease and inflammatory bowel disease, are seen with quite increased frequency. Prevention, intervention, and proper treatment is only just being recognized.

Morbidity and mortality is quite elevated and many conditions need to be vigorously and routinely checked for and diagnosed as early as possible in order to prevent long-term health consequences. Endocrine and metabolic disease contributes significantly to morbidity and is contributing to the reduced life span of women with TS and much of this morbidity can be prevented.

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Authors and Affiliations

  1. Department of Endocrinology and Medical Research Laboratories, Aarhus University Hospital, Aarhus, Denmark

    Mette H. Viuff

  2. Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark

    Claus H. Gravholt

  3. Department of Molecular Medicine, Aarhus University Hospital, Aarhus, Denmark

    Claus H. Gravholt

  4. Department of Endocrinology and Internal Medicine and Medical Research Laboratories, Aarhus University Hospital, Aarhus, Denmark

    Claus H. Gravholt

Authors
  1. Mette H. Viuff
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  2. Claus H. Gravholt
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Correspondence to Claus H. Gravholt .

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Editors and Affiliations

  1. Division of Endocrinology, Seattle Children’s Hospital, University of Washington, Seattle, WA, USA

    Patricia Y. Fechner

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Viuff, M.H., Gravholt, C.H. (2020). Endocrine and Metabolic Consequences of Turner Syndrome. In: Fechner, P. (eds) Turner Syndrome. Springer, Cham. https://doi.org/10.1007/978-3-030-34150-3_8

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  • DOI: https://doi.org/10.1007/978-3-030-34150-3_8

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