Skip to main content
SpringerLink
Log in

Vitamin D and Exercise Performance

  • Chapter
  • First Online:
Endocrinology of Physical Activity and Sport

Part of the book series: Contemporary Endocrinology ((COE))

  • 1312 Accesses

Abstract

Vitamin D is a unique vitamin which includes it having hormone-like actions. Synthesized cutaneously from UVB light or derived from the diet, vitamin D is essential for maintaining bone health and calcium homeostasis. Vitamin D is transported in the circulation bound to vitamin D-binding protein (DBP). The active form of vitamin D, 1,25(OH)2D, binds to the vitamin D receptor (VDR), a ligand-activated transcription factor, and this allows modulation of gene expression.

Recently there has been a resurgence of hypovitaminosis D that has been deemed a worldwide pandemic. This deficiency has highlighted the importance of maintaining optimal vitamin D status for non-calcemic health benefits including immunity, reproductive function, muscle function, and prevention of sarcopenia. Inverse associations with 25(OH)D concentration and increased incidence of several diseases and disorders have been established including periodontal disease, cardiovascular disease, autoimmune disorders, respiratory infections, and certain cancers. Research in athletic populations is currently limited, but findings in nonathletic populations suggest that vitamin D status is associated with jumping force and velocity. Further research is necessary to determine the impact of vitamin D status on health and performance in athletes.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 99.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 129.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 199.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Bouillon R, et al. Vitamin D and human health: lessons from vitamin D receptor null mice. Endocr Rev. 2008;29(6):726–76.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  2. Holick MF. Sunlight and vitamin D for bone health and prevention of autoimmune diseases, cancers, and cardiovascular disease. Am J Clin Nutr. 2004;80(6 Suppl):1678S–8.

    Article  CAS  PubMed  Google Scholar 

  3. McCollum EV, Davis M. The necessity of certain lipins in the diet during growth. J Biol Chem. 1913;25:167–75.

    Google Scholar 

  4. Mellanby E. An experimental investigation on rickets. Lancet. 1919;1:407–12.

    Google Scholar 

  5. McCollum EV, et al. Studies on experimental rickets. XXI. An experimental demonstration of the existence of a vitamin which promotes calcium deposition. J Biol Chem. 1922;61:293–312.

    Google Scholar 

  6. Steenbock H, Black A. Fat-soluble vitamins. XVII. The induction of growth-promoting and calcifying-properties in a ration by exposure to ultra-violet light. J Biol Chem. 1924;61:405–22.

    CAS  Google Scholar 

  7. Hess AF. The contribution of biology, chemistry and physics to the newer knowledge of rickets. Science. 1928;67(1735):333–5.

    Article  CAS  PubMed  Google Scholar 

  8. Hess AF. The prevention and cure of rickets by sunlight. Am J Public Health. 1922;12(2):104–7.

    Article  CAS  Google Scholar 

  9. Windaus A. The chemistry of irradiated ergosterol. Proc R Soc B Biol Sci. 1931;108(759):568–75.

    CAS  Google Scholar 

  10. Lips P. Vitamin D physiology. Prog Biophys Mol Biol. 2006;92(1):4–8.

    Article  CAS  PubMed  Google Scholar 

  11. DeLuca HF. Overview of general physiologic features and functions of vitamin D. Am J Clin Nutr. 2004;80:1689S–6.

    Article  CAS  PubMed  Google Scholar 

  12. Christakos S, et al. Vitamin D: molecular mechanism of action. Ann N Y Acad Sci. 2007;1116:340–8.

    Article  CAS  PubMed  Google Scholar 

  13. Stechschulte SA, Kirsner RS, Federman DG. Vitamin D: bone and beyond, rationale and recommendations for supplementation. Am J Med. 2009;122(9):793–802.

    Article  CAS  PubMed  Google Scholar 

  14. Saintonge S, Bang H, Gerber LM. Implications of a new definition of vitamin D deficiency in a multiracial us adolescent population: the National Health and Nutrition Examination Survey III. Pediatrics. 2009;123(3):797–803.

    Article  PubMed  Google Scholar 

  15. Mughal MZ, Khadilkar AV. The accrual of bone mass during childhood and puberty. Curr Opin Endocrinol Diabetes Obes. 2011;18(1):28–32.

    Article  PubMed  Google Scholar 

  16. Heaney RP. The Vitamin D requirement in health and disease. J Steroid Biochem Mol Biol. 2005;97(1–2):13–9.

    Article  CAS  PubMed  Google Scholar 

  17. Bouillon R, Van Cromphaut S, Carmeliet G. Intestinal calcium absorption: molecular vitamin D mediated mechanisms. J Cell Biochem. 2003;88(2):332–9.

    Article  CAS  PubMed  Google Scholar 

  18. Udowenko M, Trojian T. Vitamin D: extent of deficiency, effect on muscle function, bone health, performance, and injury prevention. Conn Med. 2010;74(8):477–80.

    PubMed  Google Scholar 

  19. Verstuyf A, et al. Vitamin D: a pleiotropic hormone. Kidney Int. 2010;78(2):140–5.

    Article  CAS  PubMed  Google Scholar 

  20. Larson-Meyer DE, Willis KS. Vitamin D and athletes. Curr Sports Med Rep. 2010;9(4):220–6.

    Article  PubMed  Google Scholar 

  21. Bischoff HA, et al. Effects of vitamin D and calcium supplementation on falls: a randomized controlled trial. J Bone Miner Res. 2003;18(2):343–51.

    Article  CAS  PubMed  Google Scholar 

  22. Ceglia L. Vitamin D and skeletal muscle tissue and function. Mol Asp Med. 2008;29(6):407–14.

    Article  CAS  Google Scholar 

  23. Sato Y, et al. Low-dose vitamin D prevents muscular atrophy and reduces falls and hip fractures in women after stroke: a randomized controlled trial. Cerebrovasc Dis. 2005;20(3):187–92.

    Article  CAS  PubMed  Google Scholar 

  24. Pfeifer M, Begerow B, Minne HW. Vitamin D and muscle function. Osteoporos Int. 2002;13(3):187–94.

    Article  CAS  PubMed  Google Scholar 

  25. Aquila S, et al. Human sperm anatomy: ultrastructural localization of 1alpha,25-dihydroxyvitamin D receptor and its possible role in the human male gamete. J Anat. 2008;213(5):555–64.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  26. Lewis S, et al. Vitamin D deficiency and pregnancy: from preconception to birth. Mol Nutr Food Res. 2010;54(8):1092–102.

    CAS  PubMed  Google Scholar 

  27. Grandi NC, Breitling LP, Brenner H. Vitamin D and cardiovascular disease: systematic review and meta-analysis of prospective studies. Prev Med. 2010;51(3–4):228–33.

    Article  CAS  PubMed  Google Scholar 

  28. Covic A, Voroneanu L, Goldsmith D. The effects of vitamin D therapy on left ventricular structure and function – are these the underlying explanations for improved CKD patient survival? Nephron Clin Pract. 2010;116(3):c187–95.

    Article  CAS  PubMed  Google Scholar 

  29. Pittas AG, et al. The role of vitamin D and calcium in type 2 diabetes. A systematic review and meta-analysis. J Clin Endocrinol Metab. 2007;92(6):2017–29.

    Article  CAS  PubMed  Google Scholar 

  30. Bland R, et al. Expression of 25-hydroxyvitamin D3-1alpha-hydroxylase in pancreatic islets. J Steroid Biochem Mol Biol. 2004;89–90(1–5):121–5.

    Article  PubMed  CAS  Google Scholar 

  31. Kinuta K, et al. Vitamin D is an important factor in estrogen biosynthesis of both female and male gonads. Endocrinology. 2000;141(4):1317–24.

    Article  CAS  PubMed  Google Scholar 

  32. Blomberg Jensen M, et al. Vitamin D receptor and vitamin D metabolizing enzymes are expressed in the human male reproductive tract. Hum Reprod. 2010;25(5):1303–11.

    Article  CAS  PubMed  Google Scholar 

  33. Hamilton B. Vitamin D and human skeletal muscle. Scand J Med Sci Sports. 2010;20(2):182–90.

    CAS  PubMed  PubMed Central  Google Scholar 

  34. Zitterman A. Vitamin D in preventive medicine: are we ignoring the evidence? Br J Nutr. 2003;89:552–72.

    Article  CAS  Google Scholar 

  35. Cheng JB, et al. Genetic evidence that the human CYP2R1 enzyme is a key vitamin D 25-hydroxylase. Proc Natl Acad Sci U S A. 2004;101(20):7711–5.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  36. Zhender D, et al. Extrarenal expression of 25-hydroxyvitamin D3-1α-hydroxylase. J Clin Endocrinol Metab. 2001;86(2):888–94.

    Google Scholar 

  37. Mora JR, Iwata M, von Andrian UH. Vitamin effects on the immune system: vitamins A and D take centre stage. Nat Rev Immunol. 2008;8(9):685–98.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  38. Pérez-López FR, Chedraui P, Fernández-Alonso AM. Vitamin D and aging: beyond calcium and bone metabolism. Maturitas. 2011;69(1):27–36.

    Article  PubMed  CAS  Google Scholar 

  39. Misra M, et al. Vitamin D deficiency in children and its management: review of current knowledge and recommendations. Pediatrics. 2008;122(2):398–417.

    Article  PubMed  Google Scholar 

  40. Pérez-López FR, et al. EMAS position statement: vitamin D and postmenopausal health. Maturitas. 2012;71(1):83–8.

    Article  PubMed  CAS  Google Scholar 

  41. Rosen CJ. Vitamin D insufficiency. N Engl J Med. 2011;364:248–54.

    Article  CAS  PubMed  Google Scholar 

  42. Valimaki VV, Loyttyniemi E, Valimaki MJ. Vitamin D fortification of milk products does not resolve hypovitaminosis D in young Finnish men. Eur J Clin Nutr. 2007;61(4):493–7.

    Article  PubMed  CAS  Google Scholar 

  43. Gibbs PE, Dugaiczyk A. Origin of structural domains of the serum-albumin gene family and a predicted structure of the gene for vitamin D-binding protein. Mol Biol Evol. 1987;4(4):364–79.

    CAS  PubMed  Google Scholar 

  44. Shah AB, et al. Selective inhibition of the C5a chemotactic cofactor function of the vitamin D binding protein by 1,25(OH)2 vitamin D3. Mol Immunol. 2006;43(8):1109–15.

    Article  CAS  PubMed  Google Scholar 

  45. White P, Cooke N. The multifunctional properties and characteristics of vitamin D-binding protein. Trends Endocrinol Metab. 2000;11(8):320–7.

    Article  CAS  PubMed  Google Scholar 

  46. Van Baelen H, Bouillon R, De Moor P. Vitamin D-binding protein (Gc-globulin) binds actin. J Biol Chem. 1980;255(6):2270–2.

    PubMed  Google Scholar 

  47. John GH. Plasma vitamin D-binding protein (Gc-globulin): multiple tasks. J Steroid Biochem Mol Biol. 1995;53(1–6):579–82.

    Google Scholar 

  48. Gomme PT, Bertolini J. Therapeutic potential of vitamin D-binding protein. Trends Biotechnol. 2004;22(7):340–5.

    Article  CAS  PubMed  Google Scholar 

  49. Yamamoto N, Naraparaju VR. Role of vitamin D3-binding protein in activation of mouse macrophages. J Immunol. 1996;157(4):1744–9.

    CAS  PubMed  Google Scholar 

  50. Lee WM, Galbraith RM. The extracellular actin-scavenger system and actin toxicity. N Engl J Med. 1992;326(20):1335–41.

    Article  CAS  PubMed  Google Scholar 

  51. Ceglia L, et al. Multi-step immunofluorescent analysis of vitamin D receptor loci and myosin heavy chain isoforms in human skeletal muscle. J Mol Histol. 2010;41(2–3):137–42.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  52. Ramagopalan SV, et al. A ChIP-seq defined genome-wide map of vitamin D receptor binding: associations with disease and evolution. Genome Res. 2010;20(10):1352–60.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  53. Meyer MB, et al. The human transient receptor potential vanilloid type 6 distal promoter contains multiple vitamin D receptor binding sites that mediate activation by 1,25-dihydroxyvitamin D3 in intestinal cells. Mol Endocrinol. 2006;20(6):1447–61.

    Article  CAS  PubMed  Google Scholar 

  54. Savkur RS, et al. Coactivation of the human vitamin D receptor by the peroxisome proliferator-activated receptor gamma coactivator-1 alpha. Mol Pharmacol. 2005;68(2):511–7.

    Article  CAS  PubMed  Google Scholar 

  55. Holick MF. Vitamin D status: measurement, interpretation, and clinical application. Ann Epidemiol. 2009;19(2):73–8.

    Article  PubMed  Google Scholar 

  56. Binkley N, et al. Current status of clinical 25-hydroxyvitamin D measurement: an assessment of between-laboratory agreement. Clin Chim Acta. 2010;411(23–24):1976–82.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  57. Binkley N, et al. Assay variation confounds the diagnosis of hypovitaminosis D: a call for standardization. J Clin Endocrinol Metab. 2004;89(7):3152–7.

    Article  CAS  PubMed  Google Scholar 

  58. Aloia JF, et al. Vitamin D intake to attain a desired serum 25-hydroxyvitamin D concentration. Am J Clin Nutr. 2008;87(6):1952–8.

    Article  CAS  PubMed  Google Scholar 

  59. Holick MF, Chen TC. Vitamin D deficiency: a worldwide problem with health consequences. Am J Clin Nutr. 2008;87(suppl):1080S–6.

    Article  CAS  PubMed  Google Scholar 

  60. Bischoff-Ferrari HA, et al. Estimation of optimal serum concentrations of 25-hydroxyvitamin D for multiple health outcomes. Am J Clin Nutr. 2006;84:18–28.

    Article  CAS  PubMed  Google Scholar 

  61. Cannell JJ, Hollis BW. Use of vitamin D in clinical practice. Altern Med Rev. 2008;13(1):6–20.

    PubMed  Google Scholar 

  62. Munger KL, et al. Vitamin D intake and incidence of multiple sclerosis. Neurology. 2004;62(1):60–5.

    Article  CAS  PubMed  Google Scholar 

  63. Cantorna MT. Mechanisms underlying the effect of vitamin D on the immune system. Proc Nutr Soc. 2010;69(03):286–9.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  64. Shin M-H, et al. Intake of dairy products, calcium, and vitamin D and risk of breast cancer. J Natl Cancer Inst. 2002;94(17):1301–10.

    Article  CAS  PubMed  Google Scholar 

  65. Dietrich T, et al. Association between serum concentrations of 25-hydroxyvitamin D3 and periodontal disease in the US population. Am J Clin Nutr. 2004;80(1):108–13.

    CAS  PubMed  Google Scholar 

  66. Cutolo M, Pizzorni C, Sulli A. Vitamin D endocrine system involvement in autoimmune rheumatic diseases. Autoimmun Rev. 2011;11(2):84–7.

    Article  CAS  PubMed  Google Scholar 

  67. Eikelenboom MJ, et al. Gender differences in multiple sclerosis: cytokines and vitamin D. J Neurol Sci. 2009;286(1–2):40–2.

    Article  CAS  PubMed  Google Scholar 

  68. Smolders J, et al. The relevance of vitamin D receptor gene polymorphisms for vitamin D research in multiple sclerosis. Autoimmun Rev. 2009;8(7):621–6.

    Article  CAS  PubMed  Google Scholar 

  69. Hajas A, et al. Vitamin D insufficiency in a large MCTD population. Autoimmun Rev. 2011;10(6):317–24.

    Article  CAS  PubMed  Google Scholar 

  70. Giovannucci E, et al. 25-hydroxyvitamin D and risk of myocardial infarction in men: a prospective study. Arch Intern Med. 2008;168(11):1174–80.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  71. Ravani P, et al. Vitamin D levels and patient outcome in chronic kidney disease. Kidney Int. 2009;75(1):88–95.

    Article  CAS  PubMed  Google Scholar 

  72. Vanga SR, et al. Role of vitamin D in cardiovascular health. Am J Cardiol. 2010;106:798–805.

    Article  CAS  Google Scholar 

  73. Artaza JN, Mehrotra R, Norris KC. Vitamin D and the cardiovascular system. Clin J Am Soc Nephrol. 2009;4(9):1515–22.

    Article  CAS  PubMed  Google Scholar 

  74. Nemerovski CW, et al. Vitamin D and cardiovascular disease. Pharmacotherapy. 2009;29(6):691–708.

    Article  CAS  PubMed  Google Scholar 

  75. Mitri J, et al. Effects of vitamin D and calcium supplementation on pancreatic beta cell function, insulin sensitivity, and glycemia in adults at high risk of diabetes: the Calcium and Vitamin D for Diabetes Mellitus (CaDDM) randomized controlled trial. Am J Clin Nutr. 2011;94(2):486–94.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  76. Pittas AG, Dawson-Hughes B. Vitamin D and diabetes. J Steroid Biochem Mol Biol. 2010;121(1–2):425–9.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  77. Garland CF, et al. Serum 25-hydroxyvitamin D and colon cancer: eight-year prospective study. Lancet. 1989;2(8673):1176–8.

    Article  CAS  PubMed  Google Scholar 

  78. Garland CF, Garland FC, Gorham ED. Calcium and vitamin D. Their potential roles in colon and breast cancer prevention. Ann N Y Acad Sci. 1999;889:107–19.

    Article  CAS  PubMed  Google Scholar 

  79. Gorham ED, et al. Optimal vitamin D status for colorectal cancer prevention: a quantitative meta analysis. Am J Prev Med. 2007;32(3):210–6.

    Article  PubMed  Google Scholar 

  80. Bertone-Johnson ER, et al. Plasma 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D and risk of breast cancer. Cancer Epidemiol Biomark Prev. 2005;14(8):1991–7.

    Article  CAS  Google Scholar 

  81. Krishnan AV, et al. Tissue-selective regulation of aromatase expression by calcitriol: implications for breast cancer therapy. Endocrinology. 2010;151(1):32–42.

    Article  CAS  PubMed  Google Scholar 

  82. Ginde AA, Mansbach JM, Camargo CA Jr. Vitamin D, respiratory infections and asthma. Curr Allergy Asthma Rep. 2009;9(1):81–7.

    Article  CAS  PubMed  Google Scholar 

  83. Kreutz M, et al. 1,25-dihydroxyvitamin D3 production and vitamin D3 receptor expression are developmentally regulated during differentiation of human monocytes into macrophages. Blood. 1993;82(4):1300–7.

    Article  CAS  PubMed  Google Scholar 

  84. Cantorna MT, et al. 1,25-Dihydroxycholecalciferol prevents and ameliorates symptoms of experimental murine inflammatory bowel disease. J Nutr. 2000;130:2648–52.

    Article  CAS  PubMed  Google Scholar 

  85. Cantorna MT, Hayes CE, DeLuca HF. 1,25-Dihydroxyvitamin D3 reversibly blocks the progression of relapsing encephalomyelitis, a model of multiple sclerosis. Proc Natl Acad Sci. 1996;93(15):7861–4.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  86. Cantorna MT, et al. Vitamin D status, 1,25-dihydroxyvitamin D3, and the immune system. Am J Clin Nutr. 2004;80(suppl):1717S–20.

    Article  CAS  PubMed  Google Scholar 

  87. Froicu M, et al. A crucial role for the vitamin D receptor in experimental inflammatory bowel diseases. Mol Endocrinol. 2003;17(12):2386–92.

    Article  CAS  PubMed  Google Scholar 

  88. Mithal A, et al. Global vitamin D status and determinants of hypovitaminosis D. Osteoporos Int. 2009;20(11):1807–20.

    Article  CAS  PubMed  Google Scholar 

  89. Sachan A, et al. High prevalence of vitamin D deficiency among pregnant women and their newborns in northern India. Am J Clin Nutr. 2005;81(5):1060–4.

    Article  CAS  PubMed  Google Scholar 

  90. Puri S, et al. Vitamin D status of apparently healthy schoolgirls from two different socioeconomic strata in Delhi: relation to nutrition and lifestyle. Br J Nutr. 2008;99(4):876–82.

    Article  CAS  PubMed  Google Scholar 

  91. Moussavi M, et al. Prevalence of vitamin D deficiency in Isfahani high school students in 2004. Horm Res. 2005;64(3):144–8.

    CAS  PubMed  Google Scholar 

  92. Siddiqui AM, Kamfar HZ. Prevalence of vitamin D deficiency rickets in adolescent school girls in Western region, Saudi Arabia. Saudi Med J. 2007;28(3):441–4.

    PubMed  Google Scholar 

  93. Looker AC, et al. Serum 25-hydroxyvitamin D status of the US population: 1988–1994 compared with 2000–2004. Am J Clin Nutr. 2008;88(6):1519–27.

    Article  CAS  PubMed  Google Scholar 

  94. Lehtonen-Veromaa M, et al. Vitamin D intake is low and hypovitaminosis D common in healthy 9- to 15-year-old Finnish girls. Eur J Clin Nutr. 1999;53:746–51.

    Article  CAS  PubMed  Google Scholar 

  95. Skull SA, et al. Vitamin D deficiency is common and unrecognized among recently arrived adult immigrants from The Horn of Africa. Intern Med J. 2003;33:47–51.

    Article  CAS  PubMed  Google Scholar 

  96. Hamilton B, et al. Vitamin D deficiency is endemic in Middle Eastern sportsmen. Public Health Nutr. 2010;13(10):1528–34.

    Article  PubMed  Google Scholar 

  97. Constantini NW, et al. High prevalence of vitamin D insufficiency in athletes and dancers. Clin J Sport Med. 2010;20(5):368–71.

    Article  PubMed  Google Scholar 

  98. Halliday TM, et al. Vitamin D status relative to diet, lifestyle, injury, and illness in college athletes. Med Sci Sports Exerc. 2011;43(2):335–43.

    Article  CAS  PubMed  Google Scholar 

  99. Lovell G. Vitamin D status of females in an elite gymnastics program. Clin J Sport Med. 2008;18(2):151–61.

    Article  Google Scholar 

  100. Bescos Garcia R, Rodriguez Guisado FA. Low levels of vitamin D in professional basketball players after wintertime: relationship with dietary intake of vitamin D and calcium. Nutr Hosp. 2011;26(5):945–51.

    CAS  PubMed  Google Scholar 

  101. Snellman G, et al. Seasonal genetic influence on serum 25-hydroxyvitamin D levels: a twin study. PLoS One. 2009;4(11):e7747.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  102. McKenzie RL, Liley JB, Bjorn LO. UV radiation: balancing risks and benefits. Photochem Photobiol. 2009;85(1):88–98.

    Article  CAS  PubMed  Google Scholar 

  103. Hall LM, et al. Vitamin D intake needed to maintain target serum 25-hydroxyvitamin D concentrations in participants with low sun exposure and dark skin pigmentation is substantially higher than current recommendations. J Nutr. 2010;140(3):542–50.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  104. Wortsman J, et al. Decreased bioavailability of vitamin D in obesity. Am J Clin Nutr. 2000;72:690–3.

    Article  CAS  PubMed  Google Scholar 

  105. Simpson RU, Thomas GA, Arnold AJ. Identification of 1,25-dihydroxyvitamin D3 receptors and activities in muscles. J Biol Chem. 1985;260(15):8882–91.

    CAS  PubMed  Google Scholar 

  106. Boland R. Role of vitamin D in skeletal muscle function. Endocr Rev. 1986;7(4):434–48.

    Article  CAS  PubMed  Google Scholar 

  107. Endo I, et al. Deletion of vitamin D receptor gene in mice results in abnormal skeletal muscle development with deregulated expression of myoregulatory transcription factors. Endocrinology. 2003;144(12):5138–44.

    Article  CAS  PubMed  Google Scholar 

  108. Morley JE, et al. Sarcopenia. J Lab Clin Med. 2001;137(4):231–43.

    Article  CAS  PubMed  Google Scholar 

  109. Fielding RA, et al. Sarcopenia: an undiagnosed condition in older adults. Current consensus definition: prevalence, etiology, and consequences. International working group on sarcopenia. J Am Med Dir Assoc. 2011;12(4):249–56.

    Article  PubMed  Google Scholar 

  110. Visser M, et al. Low vitamin D and high parathyroid hormone levels as determinants of loss of muscle strength and muscle mass (sarcopenia): the Longitudinal Aging Study Amsterdam. J Clin Endocrinol Metab. 2003;88(12):5766–72.

    Article  CAS  PubMed  Google Scholar 

  111. Moreira-Pfrimer LDF, et al. Treatment of vitamin D deficiency increases lower limb muscle strength in institutionalized older people independently of regular physical activity: a randomized double-blind controlled trial. Ann Nutr Metab. 2009;54(4):291–300.

    Article  CAS  PubMed  Google Scholar 

  112. El-Hajj Fuleihan G, et al. Effect of vitamin D replacement on musculoskeletal parameters in school children: a randomized controlled trial. J Clin Endocrinol Metab. 2006;91(2):405–12.

    Article  PubMed  CAS  Google Scholar 

  113. Rejnmark L. Effects of vitamin D on muscle function and performance: a review of evidence from randomized controlled trials. Ther Adv Chronic Dis. 2010;2(1):25–37.

    Article  CAS  Google Scholar 

  114. Scott D, et al. A prospective study of the associations between 25-hydroxy-vitamin D, sarcopenia progression and physical activity in older adults. Clin Endocrinol. 2010;73(5):581–7.

    Article  CAS  Google Scholar 

  115. Corless D, et al. Do vitamin D supplements improve the physical capabilities of elderly hospital patients? Age Ageing. 1985;14(2):76–84.

    Article  CAS  PubMed  Google Scholar 

  116. Latham NK, et al. A randomized, controlled trial of quadriceps resistance exercise and vitamin D in frail older people: the Frailty Interventions Trial in Elderly Subjects (FITNESS). J Am Geriatr Soc. 2003;51(3):291–9.

    Article  PubMed  Google Scholar 

  117. Cannell JJ, et al. Athletic performance and vitamin D. Med Sci Sports Exerc. 2009;41(5):1102–10.

    Article  PubMed  Google Scholar 

  118. Allen R. Effect on ultraviolet radiation on physical fitness. Arch Phys Med Rehabil. 1945;26:641–4.

    CAS  PubMed  Google Scholar 

  119. Rosentsweig J. The effect of a single suberythemic biodose of ultraviolet radiation upon the strength of college women. J Assoc Phys Ment Rehabil. 1967;21(4):131–3.

    CAS  PubMed  Google Scholar 

  120. Rosentsweig J. The effect of a single suberythemic biodose of ultraviolet radiation upon the endurance of college women. J Sports Med Phys Fitness. 1969;9(2):104–6.

    Google Scholar 

  121. Ward KA, et al. Vitamin D status and muscle function in post-menarchal adolescent girls. J Clin Endocrinol Metab. 2009;94(2):559–63.

    Article  CAS  PubMed  Google Scholar 

  122. Ward KA, et al. A randomized, controlled trial of vitamin D supplementation upon musculoskeletal health in postmenarchal females. J Clin Endocrinol Metab. 2010;95(10):4643–51.

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Athletics, University of Wyoming, Laramie, WY, USA

    Joi J. Thomas

  2. Department of Family and Consumer Services, University of Wyoming, Laramie, WY, USA

    D. Enette Larson-Meyer

Authors
  1. Joi J. Thomas
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. D. Enette Larson-Meyer
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to D. Enette Larson-Meyer .

Editor information

Editors and Affiliations

  1. Department of Exercise & Sport Science, Department of Nutrition, University of North Carolina, Chapel Hill, NC, USA

    Anthony C. Hackney

  2. Heidi Rothberg Sport Medicine Center, Shaare Zedek Medical Center, Jerusalem, Jerusalem, Israel

    Naama W. Constantini

Rights and permissions

Reprints and permissions

Copyright information

© 2020 Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Thomas, J.J., Larson-Meyer, D.E. (2020). Vitamin D and Exercise Performance. In: Hackney, A., Constantini, N. (eds) Endocrinology of Physical Activity and Sport. Contemporary Endocrinology. Humana, Cham. https://doi.org/10.1007/978-3-030-33376-8_18

Download citation

  • DOI: https://doi.org/10.1007/978-3-030-33376-8_18

  • Published:

  • Publisher Name: Humana, Cham

  • Print ISBN: 978-3-030-33375-1

  • Online ISBN: 978-3-030-33376-8

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation