Abstract
The genome expresses itself into a given phenotype in a complex way. Actually, at the basic level, the genome sequence codes for its own translating machinery. It determines the birth of a cellular machinery responsible, in turn, for gene regulation and expression. A particular gene, for instance, codes for RNA polymerase whose function is to transcribe the genes into messenger RNA. Without RNA polymerase there is no messenger RNA, we are faced with the absence of cellular life. However, RNA polymerase is necessary for its very synthesis because it transcribes its gene. Hence the essential circularity that characterizes living organisms. The cellular machinery “represents”, step by step, the genome into an organism realizing the final stage of what we call the embodiment process. In this sense, the genome and the cellular machinery really interact by establishing an evolving and coupled network: as we shall see one of the key results of this interaction is represented by the continuous engraving (through selection) at the level of the organisms of specific formats: among them we can distinguish, first of all, the formats relative to the architectures of sensorial perception. In this way the circularity proper to life necessarily unfolds in the conditions of Reflexivity.
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Carsetti, A. (2020). Drawing a Software Space for Natural Evolution. In: Metabiology. Studies in Applied Philosophy, Epistemology and Rational Ethics, vol 50. Springer, Cham. https://doi.org/10.1007/978-3-030-32718-7_2
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