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Two Meanings of Reverse Vaccinology and the Empirical Nature of Vaccine Science

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Abstract

The remarkable success of molecular and structural biology in elucidating many biological phenomena has had the unfortunate consequence that many scientists are no longer aware of the empirical foundations of all experimental science. This is evident from published statements that claim, for instance, that rational design represents “the only approach that can elevate vaccine research from an empirical exercise to a scientific discipline” (Karlsson-Hedestam et al. 2008).

Vaccine, 2011, 29, 7875.

Marc H V Van Regenmortel

Copyright © 2011 Elsevier

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Van Regenmortel, M.H.V. (2019). Two Meanings of Reverse Vaccinology and the Empirical Nature of Vaccine Science. In: HIV/AIDS: Immunochemistry, Reductionism and Vaccine Design. Springer, Cham. https://doi.org/10.1007/978-3-030-32459-9_13

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