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Spatial-Frequency Non-local Convolutional LSTM Network for pRCC Classification

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Medical Image Computing and Computer Assisted Intervention – MICCAI 2019 (MICCAI 2019)

Abstract

The accurate classification of 3D medical images is a challenging task for current deep learning methods. Deep learning models struggle to extract features when the data size is small and the data dimension is large. To solve this problem, we develop a spatial-frequency non-local convolutional LSTM network for 3D image classification. Compared to traditional networks, the proposed model has the ability to extract features from both the spatial and frequency domains, which allows the frequency-domain features to contribute to the classification. Furthermore, the non-local blocks in our architecture enable it to capture the long-range dependencies directly in the feature space. Finally, to simplify the classification task and improve the performance, we utilize a two-stage framework that localizes lesions in the first step, and classifies them in the second. We evaluate our method on a challenging and important clinical task, i.e, the differentiation of papillary renal cell carcinoma (pRCC) into subtype 1 and subtype 2. To the best of our knowledge, this is the first time that the advantage of synthesizing spatial- and frequency-domain features by deep learning networks for medical image classification has been demonstrated. Experimental results demonstrate that the proposed method achieves competitive and often superior performance compared to state-of-the-art networks and three clinical experts.

Y. Zhao and Y. Liu—Contributed equally.

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References

  1. Gupta, K., et al.: Epidemiologic and socioeconomic burden of metastatic renal cell carcinoma (mRCC): a literature review. Cancer Treat. Rev. 34(3), 193–205 (2008)

    Article  Google Scholar 

  2. Hazlett, H.C., et al.: Early brain development in infants at high risk for autism spectrum disorder. Nature 542(7641), 348 (2017)

    Article  Google Scholar 

  3. He, K., et al.: Deep residual learning for image recognition. In: Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition, pp. 770–778 (2016)

    Google Scholar 

  4. Huang, G., et al.: Densely connected convolutional networks. In: Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition, pp. 4700–4708 (2017)

    Google Scholar 

  5. Klatte, T., et al.: Cytogenetic and molecular tumor profiling for type 1 and type 2 papillary renal cell carcinoma. Clin. Cancer Res. 15(4), 1162–1169 (2009)

    Article  Google Scholar 

  6. LeCun, Y., Bengio, Y., Hinton, G.: Deep learning. Nature 521(7553), 436 (2015)

    Article  Google Scholar 

  7. Novikov, A.A., et al.: Deep sequential segmentation of organs in volumetric medical scans. IEEE Trans. Med. Imaging 36, 1359–1371 (2018)

    Google Scholar 

  8. Ronneberger, O., Fischer, P., Brox, T.: U-net: convolutional networks for biomedical image segmentation. In: Navab, N., Hornegger, J., Wells, W.M., Frangi, A.F. (eds.) MICCAI 2015. LNCS, vol. 9351, pp. 234–241. Springer, Cham (2015). https://doi.org/10.1007/978-3-319-24574-4_28

    Chapter  Google Scholar 

  9. Roth, H.R., et al.: Improving computer-aided detection using convolutional neural networks and random view aggregation. IEEE Trans. Med. Imaging 35(5), 1170–1181 (2016)

    Article  Google Scholar 

  10. Schlemper, J., et al.: Cardiac MR segmentation from undersampled k-space using deep latent representation learning. In: Frangi, A.F., Schnabel, J.A., Davatzikos, C., Alberola-López, C., Fichtinger, G. (eds.) MICCAI 2018. LNCS, vol. 11070, pp. 259–267. Springer, Cham (2018). https://doi.org/10.1007/978-3-030-00928-1_30

    Chapter  Google Scholar 

  11. Suk, H.I., et al.: Latent feature representation with stacked auto-encoder for AD/MCI diagnosis. Brain Struct. Func. 220(2), 841–859 (2015)

    Article  Google Scholar 

  12. Szegedy, C., et al.: Going deeper with convolutions. In: Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition, pp. 1–9 (2015)

    Google Scholar 

  13. Jimenez-del Toro, O., et al.: Cloud-based evaluation of anatomical structure segmentation and landmark detection algorithms: visceral anatomy benchmarks. IEEE Trans. Med. Imaging 35(11), 2459–2475 (2016)

    Article  Google Scholar 

  14. Varghese, B.A., et al.: Differentiation of predominantly solid enhancing lipid-poor renal cell masses by use of contrast-enhanced CT: evaluating the role of texture in tumor subtyping. Am. J. Roentgenol. 211(6), W288–W296 (2018)

    Article  MathSciNet  Google Scholar 

  15. Wang, X., et al.: Non-local neural networks. In: Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition, pp. 7794–7803 (2018)

    Google Scholar 

  16. Zhu, B., et al.: Image reconstruction by domain-transform manifold learning. Nature 555(7697), 487 (2018)

    Article  Google Scholar 

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Correspondence to Xiaobin Hu .

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Zhao, Y. et al. (2019). Spatial-Frequency Non-local Convolutional LSTM Network for pRCC Classification. In: Shen, D., et al. Medical Image Computing and Computer Assisted Intervention – MICCAI 2019. MICCAI 2019. Lecture Notes in Computer Science(), vol 11769. Springer, Cham. https://doi.org/10.1007/978-3-030-32226-7_3

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  • DOI: https://doi.org/10.1007/978-3-030-32226-7_3

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-32225-0

  • Online ISBN: 978-3-030-32226-7

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