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Decellularized Extracellular Matrix-Based Bioinks

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3D Bioprinting

Abstract

Decellularized extracellular matrix (dECM)-based bioink enables the improved recapitulation of actual microenvironments when compared with conventional bioinks. When applied to the 3D printing technology, dECM facilitate the engineering of more realistic living constructs, including elaborate microarchitecture as well as biochemical environments of target tissues/organs. This chapter provides the fundamental knowledge of a dECM bioink such as the sources of native tissue/organ for decellularization, evaluation of decellularization process, and safety. Besides, by introducing the various applications of dECM bioinks, the superiority of dECM bioinks compared with conventional bioinks is covered.

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Author information

Authors and Affiliations

  1. Department of Mechanical Engineering and Division of Integrative Biosciences and Biotechnology, Pohang University of Science and Technology, Pohang, Korea (Republic of)

    Dong-Woo Cho

  2. Future IT Innovation Laboratory, Pohang University of Science and Technology, Pohang, Korea (Republic of)

    Byoung Soo Kim

  3. Department of Creative IT Engineering and Mechanical Engineering, Pohang University of Science and Technology, Pohang, Korea (Republic of)

    Jinah Jang

  4. Department of Mechanical Engineering, Pohang University of Science and Technology, Pohang, Korea (Republic of)

    Ge Gao & Narendra K. Singh

  5. Division of Integrative Biosciences and Biotechnology, Pohang University of Science and Technology, Pohang, Korea (Republic of)

    Wonil Han

Authors
  1. Dong-Woo Cho
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  2. Byoung Soo Kim
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  3. Jinah Jang
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  4. Ge Gao
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  5. Wonil Han
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  6. Narendra K. Singh
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Cho, DW., Kim, B.S., Jang, J., Gao, G., Han, W., Singh, N.K. (2019). Decellularized Extracellular Matrix-Based Bioinks. In: 3D Bioprinting. Springer, Cham. https://doi.org/10.1007/978-3-030-32222-9_6

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