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Evaluation of Excised Lymph Nodes

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Book cover Practical Lymph Node and Bone Marrow Pathology

Part of the book series: Practical Anatomic Pathology ((PAP))

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Abstract

Excisional biopsy of lymph node is a routine procedure for evaluating lymphoid pathology in patients with lymphadenopathy. A standard workup to rule out lymphoma is a comprehensive study, including histologic evaluation, immunohistochemical analysis, flow cytometry, cytogenetic study (i.e., FISH for targeted cytogenetic abnormalities), and/or molecular diagnostic tests. This chapter covers some general principles for handling specimens of lymphoma workup, clinical correlation with types of lymphoma, common morphological patterns of lymphomas or mimics, and judicial application of ancillary tests, based on clinical presentations and initial morphologic evaluation.

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Author information

Authors and Affiliations

  1. Department of Pathology, Yale University School of Medicine, New Haven, CT, USA

    Zenggang Pan

  2. Department of Hematopathology, University of Southern California, Children’s Hospital Los Angeles, Los Angeles, CA, USA

    Le Aye

  3. Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA

    Imran N. Siddiqi

  4. Department of Pathology, Duke University School of Medicine and Duke Health System, Durham, NC, USA

    Endi Wang

Authors
  1. Zenggang Pan
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  2. Le Aye
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  3. Imran N. Siddiqi
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  4. Endi Wang
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Corresponding author

Correspondence to Zenggang Pan .

Editor information

Editors and Affiliations

  1. Department of Pathology, Duke University School of Medicine and Duke Health System, Durham, NC, USA

    Endi Wang

  2. Department of Pathology, Duke University School of Medicine and Duke Health System, Durham, NC, USA

    Anand Shreeram Lagoo

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Pan, Z., Aye, L., Siddiqi, I.N., Wang, E. (2020). Evaluation of Excised Lymph Nodes. In: Wang, E., Lagoo, A.S. (eds) Practical Lymph Node and Bone Marrow Pathology. Practical Anatomic Pathology. Springer, Cham. https://doi.org/10.1007/978-3-030-32189-5_3

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  • DOI: https://doi.org/10.1007/978-3-030-32189-5_3

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-32188-8

  • Online ISBN: 978-3-030-32189-5

  • eBook Packages: MedicineMedicine (R0)

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