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Large Airways

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Pediatric Body MRI

Abstract

In recent years, magnetic resonance (MR) imaging has become the preferred noninvasive method to assess various congenital and acquired pediatric large airway disorders. Recent technical advances have made MR imaging of the large airways a feasible alternative imaging option to computed tomography (CT). MR imaging provides better contrast-to-noise ratio and soft tissue characterization than CT, facilitating differential diagnosis of soft tissue masses around the large airways in the neck and mediastinal regions. Moreover, MR imaging enables dynamic acquisitions (cine-MR imaging), which are mandatory to assess large airway collapse in children with tracheobronchomalacia. Cine-MR imaging can be performed during specific breathing maneuvers, usually rehearsed in training sessions before the MR imaging, to visualize large airway collapse. Finally, the ability of MR imaging to provide functional information regarding tissue cellularity and inflammation has promoted its use in infectious and inflammatory disorders as well as neoplasms of the large airways. This chapter presents up-to-date imaging techniques for MR imaging of the pediatric large airways followed by characteristic MR imaging findings in a spectrum of pediatric large airway disorders encountered in daily clinical practice.

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References

  1. Tiddens HAWM, Kuo W, van Straten M, Ciet P. Paediatric lung imaging: the times they are a-changin. Eur Respir Rev. 2018;27(147):170097. https://doi.org/10.1183/16000617.0097-2017.

    Article  PubMed  Google Scholar 

  2. Ciet P, Tiddens HAWM, Wielopolski PA, et al. Magnetic resonance imaging in children: common problems and possible solutions for lung and airways imaging. Pediatr Radiol. 2015;45(13):1901–15.

    Article  PubMed  PubMed Central  Google Scholar 

  3. Baez JC, Ciet P, Mulkern R, Seethamraju RT, Lee EY. Pediatric chest MR imaging: lung and airways. Magn Reson Imaging Clin N Am. 2015;23(2):337–49.

    Article  PubMed  Google Scholar 

  4. Lee EY, Zucker EJ, Restrepo R, Daltro P, Boiselle PM. Advanced large airway CT imaging in children: evolution from axial to 4-D assessment. Pediatr Radiol. 2013;43(3):285–97.

    Article  PubMed  Google Scholar 

  5. Liszewski MC, Hersman FW, Altes TA, Ohno Y, Ciet P, Warfield SK, Lee EY. Magnetic resonance imaging of pediatric lung parenchyma, airways, vasculature, ventilation, and perfusion: state of the art. Radiol Clin North Am. 2013;51(4):555–82. Review.

    Article  PubMed  Google Scholar 

  6. Baez JC, Seethamraju RT, Mulkern R, Ciet P, Lee EY. Pediatric chest MR imaging: sedation, techniques, and extracardiac vessels. Magn Reson Imaging Clin N Am. 2015;23(2):321–35.

    Article  PubMed  Google Scholar 

  7. Edwards AD, Arthurs OJ. Paediatric MRI under sedation: is it necessary? What is the evidence for the alternatives? Pediatr Radiol. 2011;41(11):1353–64.

    Article  PubMed  Google Scholar 

  8. Lutterbey G, Wattjes MP, Doerr D, Fischer NJ, Gieseke J, Schild HH. Atelectasis in children undergoing either propofol infusion or positive pressure ventilation anesthesia for magnetic resonance imaging. Pediatr Anesth. 2007;17(2):121–5.

    Article  Google Scholar 

  9. Salamon E, Lever S, Kuo W, Ciet P, Tiddens HA. Spirometer guided chest imaging in children: it is worth the effort! Pediatr Pulmonol. 2017;52(1):48–56.

    Article  PubMed  Google Scholar 

  10. Gai ND, Malayeri A, Agarwal H, Evers R, Bluemke D. Evaluation of optimized breath-hold and free-breathing 3D ultrashort echo time contrast agent-free MRI of the human lung. J Magn Reson Imaging. 2016;43(5):1230–8.

    Article  PubMed  Google Scholar 

  11. Dournes G, Grodzki D, Macey J, Girodet PO, Fayon M, Chateil JF, et al. Quiet submillimeter MR imaging of the lung is feasible with a PETRA sequence at 1.5 T. Radiology. 2015;279(1):328.

    Article  Google Scholar 

  12. Chandarana H, Block KT, Winfeld MJ, Lala SV, Mazori D, Giuffrida E, et al. Free-breathing contrast-enhanced T1-weighted gradient-echo imaging with radial k-space sampling for paediatric abdominopelvic MRI. Eur Radiol. 2014;24(2):320–6.

    Article  PubMed  Google Scholar 

  13. Kishida Y, Koyama H, Seki S, Yoshikawa T, Kyotani K, Okuaki T, et al. Comparison of fat suppression capability for chest MR imaging with Dixon, SPAIR and STIR techniques at 3 tesla MR system. Magn Reson Imaging. 2018;47:89–96.

    Article  PubMed  Google Scholar 

  14. Gibiino F, Sacolick L, Menini A, Landini L, Wiesinger F. Free-breathing, zero-TE MR lung imaging. MAGMA. 2015;28(3):207–15.

    Article  PubMed  Google Scholar 

  15. Kumar S, Rai R, Stemmer A, Josan S, Holloway L, Vinod S, et al. Feasibility of free breathing lung MRI for radiotherapy using non-Cartesian k-space acquisition schemes. Br J Radiol. 2017;90(1080):20170037.

    Article  PubMed  PubMed Central  Google Scholar 

  16. Bates AJ, Higano NS, Hysinger EB, et al. Quantitative assessment of regional dynamic airway collapse in neonates via retrospectively respiratory-gated 1H ultrashort echo time MRI. J Magn Reson Imaging. 2019;49(3):659–67.

    Article  PubMed  Google Scholar 

  17. Liszewski MC, Ciet P, Lee EY. MR imaging of lungs and airways in children. Magn Reson Imaging Clin N Am. 2019;27(2):201–25.

    Article  PubMed  Google Scholar 

  18. Ciet P, Wielopolski P, Manniesing R, Lever S, de Bruijne M, Morana G, et al. Spirometer-controlled cine magnetic resonance imaging used to diagnose tracheobronchomalacia in paediatric patients. Eur Respir J. 2014;43(1):115–24.

    Article  PubMed  Google Scholar 

  19. Ciet P, Boiselle PM, Heidinger B, et al. Cine MRI of tracheal dynamics in healthy volunteers and patients with tracheobronchomalacia. AJR Am J Roentgenol. 2017;209(4):757–61.

    Article  PubMed  Google Scholar 

  20. Berrocal T, Madrid C, Novo S, Gutiérrez J, Arjonilla A, Gómez-León N. Congenital anomalies of the tracheobronchial tree, lung, and mediastinum: embryology, radiology, and pathology. Radiographics. 2004;24:e17.

    Article  PubMed  Google Scholar 

  21. Holbert JM, Strollo DC. Imaging of the normal trachea. J Thorac Imaging. 1995;10(3):171–9.

    Article  CAS  PubMed  Google Scholar 

  22. Kotecha S. Lung growth for beginners. Paediatr Respir Rev. 2000;1(4):308–13.

    CAS  PubMed  Google Scholar 

  23. Biyyam DR, Chapman T, Ferguson MR, Deutsch G, Dighe MK. Congenital lung abnormalities: embryologic features, prenatal diagnosis, and postnatal radiologic-pathologic correlation. Radiographics. 2010;30(6):1721–38.

    Article  PubMed  Google Scholar 

  24. Griscom NT, Wohl ME. Dimensions of the growing trachea related to body height. Am Rev Respir Dis. 1985;131(6):840–4.

    CAS  PubMed  Google Scholar 

  25. Griscom NT, Wohl ME. Dimensions of the growing trachea related to age and gender. AJR Am J Roentgenol. 1986;146(2):233–7.

    Article  CAS  PubMed  Google Scholar 

  26. Jeffrery PK. The development of large and small airways. Am J Respir Crit Care Med. 1988;157(5 Part 2):S174–80.

    Google Scholar 

  27. Lawrence DA, Branson B, Oliva I, Rubinowitz A. The wonderful world of the windpipe: a review of central airway anatomy and pathology. Can Assoc Radiol J. 2015;66(1):30–43.

    Article  PubMed  Google Scholar 

  28. Boiselle PM. Imaging of the large airways. Clin Chest Med. 2008;29(1):181–93.

    Article  PubMed  Google Scholar 

  29. Boiselle PM, Lee KS, Ernst A. Multidetector CT of the central airways. J Thorac Imaging. 2005;20(3):186–95.

    Article  PubMed  Google Scholar 

  30. Breatnach E, Abbott GC, Fraser RG. Dimensions of the normal human trachea. AJR Am J Roentgenol. 1984;142(5):903–6.

    Article  CAS  PubMed  Google Scholar 

  31. Hewitt RJ, Butler CR, Maughan EF, Elliott MJ. Congenital tracheobronchial stenosis. Semin Pediatr Surg. 2016;25(3):144–9.

    Article  PubMed  Google Scholar 

  32. Uchida DA, Morgan-wallace V, Richards K, Seidelman J, Muntz HR. Congenital tracheal stenosis masquerading as asthma in an adolescent: the value of spirometry. Clin Pediatr (Phila). 2009;48(4):432–4.

    Article  Google Scholar 

  33. Applegate KE, Goske MJ, Pierce G, Murphy D. Situs revisited: imaging of the heterotaxy syndrome. Radiographics. 2013;19(4):837–52; discussion 853–4.

    Article  Google Scholar 

  34. Yoneyama H, Kondo C, Yamasaki A, Nakanishi T, Sakai S. Comparison of situs ambiguous patterns between heterotaxy syndromes with polysplenia and asplenia. Eur J Radiol. 2015;84(11):2301–6.

    Article  PubMed  Google Scholar 

  35. Loomba R, Shah PH, Anderson RH, Arora Y. Radiologic considerations in heterotaxy: the need for detailed anatomic evaluation. Cureus. 2016;8(1):e470. https://doi.org/10.7759/cureus.470.

    Article  PubMed  PubMed Central  Google Scholar 

  36. Shapiro AJ, Zariwala MA, Ferkol T, Davis SD, Sagel SD, Dell SD, et al.; Genetic Disorders of Mucociliary Clearance Consortium. Diagnosis, monitoring, and treatment of primary ciliary dyskinesia: PCD foundation consensus recommendations based on state of the art review. Pediatr Pulmonol. 2016;51(2):115–32. Review.

    Article  Google Scholar 

  37. Donnelly LF, Jones BV, Strife JL. Imaging of pediatric tongue abnormalities. AJR Am J Roentgenol. 2000;175(2):489–93.

    Article  CAS  PubMed  Google Scholar 

  38. Lo Casto A, Salerno S, Cannizzaro F, Caronia A, Bencivinni F, Barbiera F, et al. MRI findings in lingual venous malformations. Dentomaxillofacial Radiol. 2003;32(5):333–6.

    Article  CAS  Google Scholar 

  39. Perkins JA. Overview of macroglossia and its treatment. Curr Opin Otolaryngol Head Neck Surg. 2009;17(6):460–5.

    Article  PubMed  Google Scholar 

  40. Fujioka M, Young LW, Giardany BR. Radiographic evaluation of adenoidal size in children: ratio. AJR Am J Roentgenol. 1979;133(3):401–4.

    Article  CAS  PubMed  Google Scholar 

  41. Fernbach SK, Brouillette RT, Riggs TW, Hunt CE. Radiologic evaluation of adenoids and tonsils in children with obstructive sleep apnea: plain films and fluoroscopy. Pediatr Radiol. 1983;13(5):258–65.

    Article  CAS  PubMed  Google Scholar 

  42. Fricke BL, Donnelly LF, Shott SR, Kalra M, Poe SA, Chini BA, Amin RS. Comparison of lingual tonsil size as depicted on MR imaging between children with obstructive sleep apnea despite previous tonsillectomy and adenoidectomy and normal controls. Pediatr Radiol. 2006;36(6):518–23.

    Article  PubMed  Google Scholar 

  43. Donnelly LF, Casper KA, Chen B. Correlation on cine MR imaging of size of adenoid and palatine tonsils with degree of upper airway motion in asymptomatic sedated children. AJR Am J Roentgenol. 2002;179(2):503–8.

    Article  PubMed  Google Scholar 

  44. John SD, Swischuk LE. Stridor and upper airway obstruction in infants and children. Radiographics. 1992;12(4):625–43.

    Article  CAS  PubMed  Google Scholar 

  45. Schroeder JW, Holinger LD. Congenital laryngeal stenosis. Otolaryngol Clin North Am. 2008;41(5):865–75.

    Article  PubMed  Google Scholar 

  46. Sanford E, Saadai P, Lee H, Slavotinek A. Congenital high airway obstruction sequence (CHAOS): a new case and a review of phenotypic features. Am J Med Genet A. 2012;158A(12):3126–36.

    Article  PubMed  Google Scholar 

  47. Ryan G, Somme S, Crombleholme TM. Airway compromise in the fetus and neonate: prenatal assessment and perinatal management. Semin Fetal Neonatal Med. 2016;21(4):230–9.

    Article  PubMed  Google Scholar 

  48. Guimaraes CV, Linam LE, Kline-Fath BM, Donnelly LF, Calvo-Garcia MA, Rubio EI, et al. Prenatal MRI findings of fetuses with congenital high airway obstruction sequence. Korean J Radiol. 2009;10(2):129–34.

    Article  PubMed  PubMed Central  Google Scholar 

  49. Goyal A, Jones MO, Couriel JM, Losty PD. Oesophageal atresia and tracheo-oesophageal fistula. Arch Dis Child Fetal Neonatal Ed. 2006;91(5):381–4. Review.

    Article  Google Scholar 

  50. Garge S, Rao KL, Bawa M. The role of preoperative CT scan in patients with tracheoesophageal fistula: a review. J Pediatr Surg. 2013;48(9):1966–71.

    Article  PubMed  Google Scholar 

  51. Hochart V, Verpillat P, Langlois C, Garabedian C, Bigot J, Debarge VH, et al. The contribution of fetal MR imaging to the assessment of oesophageal atresia. Eur Radiol. 2015;25(2):306–14.

    Article  CAS  PubMed  Google Scholar 

  52. Higano NS, Bates AJ, Tkach JA, Fleck RJ, Lim FY, Woods JC, Kingma PS. Pre- and post-operative visualization of neonatal esophageal atresia / tracheoesophageal fistula via magnetic resonance imaging. J Pediatr Surg Case Rep. 2018;29:5–8.

    Article  PubMed  Google Scholar 

  53. Kovesi T, Rubin S. Long-term complications of congenital esophageal atresia and/or tracheoesophageal fistula. Chest. 2004;126(3):915–25.

    Article  PubMed  Google Scholar 

  54. Yedururi S, Guillerman RP, Chung T, Braverman RM, Dishop MK, Giannoni CM, Krishnamurthy R. Multimodality imaging of tracheobronchial disorders in children. Radiographics. 2008;28(3):e29.

    Article  PubMed  Google Scholar 

  55. Desir A, Ghaye B. Congenital abnormalities of intrathoracic airways. Radiol Clin North Am. 2009;47(2):203–25.

    Article  PubMed  Google Scholar 

  56. Ghaye B, Szapiro D, Fanchamps J-M, Dondelinger RF. Congenital bronchial abnormalities revisited. Radiographics. 2001;21(1):105–19.

    Article  CAS  PubMed  Google Scholar 

  57. Doolittle AM, Mair EA. Tracheal bronchus: classification, endoscopic analysis, and airway management. Otolaryngol Neck Surg. 2002;126(3):240–3.

    Article  Google Scholar 

  58. Newman B. Congenital bronchopulmonary foregut malformations: concepts and controversies. Pediatr Radiol. 2006;36(8):773–91.

    Article  PubMed  Google Scholar 

  59. Kinsella BD, Sissons G, Williams MP. The radiological imaging of bronchial atresia. Br J Radiol. 1992;65(776):681–5. Review.

    Article  CAS  PubMed  Google Scholar 

  60. Gipson MG, Kristopher W, Hurth KM. Bronchial atresia. Radiographics. 2009;29(5):1531–5.

    Article  PubMed  Google Scholar 

  61. Thacker PG, Rao AG, Hill JG, Lee EY. Congenital lung anomalies in children and adults: current concepts and imaging findings. Radiol Clin North Am. 2014;52(1):155–81.

    Article  PubMed  Google Scholar 

  62. Fievet L, D’Journo XB, Guys JM, Thomas PA, De Lagausie P. Bronchogenic cyst: best time for surgery? Ann Thorac Surg. 2012;94(5):1695–9.

    Article  PubMed  Google Scholar 

  63. Kirmani B, Kirmani B, Sogliani F. Should asymptomatic bronchogenic cysts in adults be treated conservatively or with surgery? Interact Cardiovasc Thorac Surg. 2010;11(5):649–59.

    Article  PubMed  Google Scholar 

  64. Hall NJ, Stanton MP. Long-term outcomes of congenital lung malformations. Semin Pediatr Surg. 2017;26(5):311–6.

    Article  PubMed  Google Scholar 

  65. Malhotra A, White DP. Obstructive sleep apnoea. Lancet. 2002;360(9328):237–45. Review

    Article  PubMed  Google Scholar 

  66. Chang SJ, Chae KY. Obstructive sleep apnea syndrome in children: epidemiology, pathophysiology, diagnosis and sequelae. Korean J Pediatr. 2010;53(10):863–71.

    Article  PubMed  PubMed Central  Google Scholar 

  67. Thakkar K, Yao M. Diagnostic studies in obstructive sleep apnea. Otolaryngol Clin North Am. 2007;40(4):785–805.

    Article  PubMed  Google Scholar 

  68. Mello Junior CF, Guimarães Filho HA, Gomes CA, Paiva CC. Radiological findings in patients with obstructive sleep apnea. J Bras Pneumol. 2013;39(1):98–101. [Article in English, Portuguese].

    Article  PubMed  Google Scholar 

  69. Donnelly LF. Obstructive sleep apnea in pediatric patients: evaluation with cine MR sleep studies. Radiology. 2007;236(3):768–78.

    Article  Google Scholar 

  70. Brockbank JC. Update on pathophysiology and treatment of childhood obstructive sleep apnea syndrome. Paediatr Respir Rev. 2017;24:21–3.

    PubMed  Google Scholar 

  71. Torretta S, Rosazza C, Pace ME, Iofrida E, Marchisio P. Impact of adenotonsillectomy on pediatric quality of life: review of the literature. Ital J Pediatr. 2017;43(1):107.

    Article  PubMed  PubMed Central  Google Scholar 

  72. Kaditis AG, Alonso Alvarez ML, Boudewyns A, Alexopoulos EI, Ersu R, Joosten K, et al. Obstructive sleep disordered breathing in 2- to 18-year-old children: diagnosis and management. Eur Respir J. 2016;47(1):69–94.

    Article  PubMed  Google Scholar 

  73. Lee EY, Litmanovich D, Boiselle PM. Multidetector CT evaluation of tracheobronchomalacia. Radiol Clin North Am. 2009;47(2):261–9. Review.

    Article  PubMed  Google Scholar 

  74. Carden KA, Boiselle PM, Waltz DA, Ernst A. Tracheomalacia and tracheobronchomalacia in children and adults: an in-depth review. Chest. 2005;127(3):984–1005.

    Article  PubMed  Google Scholar 

  75. Lee KS, Sun MR, Ernst A, Feller-Kopman D, Majid A, Boiselle PM. Comparison of dynamic expiratory CT with bronchoscopy for diagnosing airway malacia: a pilot evaluation. Chest. 2007;131(3):758–64.

    Article  PubMed  Google Scholar 

  76. Boiselle PM, O’Donnell CR, Bankier AA, Ernst A, Millet ME, Potemkin A, Loring SH. Tracheal collapsibility in healthy volunteers during forced expiration: assessment with multidetector CT. Radiology. 2009;252(1):255–62.

    Article  PubMed  PubMed Central  Google Scholar 

  77. Fraga JC, Jennings RW, Kim PC. Pediatric tracheomalacia. Semin Pediatr Surg. 2016;25(3):156–64.

    Article  PubMed  Google Scholar 

  78. Snijders D, Barbato A. An update on diagnosis of tracheomalacia in children. Eur J Pediatr Surg. 2015;25(4):333–5.

    Article  PubMed  Google Scholar 

  79. Centers for Disease Control and Prevention. Surveillance, Epidemiology, and Outbreak Investigations Branch. Division of Tuberculosis Elimination. Epidemiology of Pediatric Tuberculosis in the United States, 1993–2016. 21 Jun 2017. https://www.cdc.gov/tb/publications/slidesets/pediatrictb/PediatricTB_SlideSet_TextOnly_2016.pdf. Accessed 29 July 2019.

  80. European Centre for Disease Prevention and Control/WHO Regional Office for Europe. Tuberculosis surveillance and monitoring in Europe. Report 2018. 2016 data. 2018. Sotkcholm: European Centere for Disease Prevention and Control; 2018. https://ecdc.europa.eu/sites/portal/files/documents/ecdc-tuberculosis-surveillance-monitoring-Europe-2018-rev1.pdf. Accessed 29 July 2019.

  81. Fonseca-Santos J. Tuberculosis in children. Eur J Radiol. 2005;55(2):202–8.

    Article  PubMed  Google Scholar 

  82. Burrill J, Williams CJ, Bain G, Conder G, Hine AL, Misra RR. Tuberculosis: a radiologic review. Radiographics. 2007;27(5):1255–73.

    Article  PubMed  Google Scholar 

  83. Nachiappan AC, Rahbar K, Shi X, Guy ES, Mortani Barbosa EJ Jr, Shroff GS, et al. Pulmonary tuberculosis: role of radiology in diagnosis and management. Radiographics. 2017;37(1):52–72.

    Article  PubMed  Google Scholar 

  84. Rizzi EB, Schinina’ V, Cristofaro M, Goletti D, Palmieri F, Bevilacqua N, et al. Detection of pulmonary tuberculosis: comparing MR imaging with HRCT. BMC Infect Dis. 2011;11:243. https://doi.org/10.1186/1471-2334-11-243.

    Article  PubMed  Google Scholar 

  85. Sodhi KS, Sharma M, Saxena AK, Mathew JL, Singh M, Khandelwal N. MRI in thoracic tuberculosis of children. Indian J Pediatr. 2017;84(9):670–6.

    Article  PubMed  Google Scholar 

  86. Gaensbauer J, Broadhurst R. Recent innovations in diagnosis and treatment of pediatric tuberculosis. Curr Infect Dis Rep. 2019;21(1):4. https://doi.org/10.1007/s11908-019-0662-0.

    Article  PubMed  Google Scholar 

  87. Chu JH, Feudtner C, Heydon K, Walsh TJ, Zaoutis TE. Hospitalizations for endemic mycoses: a population-based national study. Clin Infect Dis. 2006;42(6):822–5.

    Article  PubMed  Google Scholar 

  88. Kirchner SG, Hernanz-Schulman M, Stein SM, Wright PF, Heller RM. Imaging of pediatric mediastinal histoplasmosis. Radiographics. 1991;11(3):365–81.

    Article  CAS  PubMed  Google Scholar 

  89. Rossi SE, McAdams HP, Rosado-de-Christenson ML, Franks TJ, Galvin JR. Fibrosing mediastinitis. Radiographics. 2001;21(3):737–57. Review.

    Article  CAS  PubMed  Google Scholar 

  90. Wheat LJ, Freifeld AG, Kleiman MB, Baddley JW, McKinsey DS, Loyd JE, Kauffman CA. Infectious Diseases Society of America. Clinical practice guidelines for the management of patients with histoplasmosis: 2007 update by the Infectious Diseases Society of America. Clin Infect Dis. 2007;45(7):807–25.

    Article  PubMed  Google Scholar 

  91. Güneyli S, Ceylan N, Bayraktaroǧlu S, Acar T, Savaş R. Imaging findings of vascular lesions in the head and neck. Diagn Interv Radiol. 2014;20(5):432–7.

    Article  PubMed  PubMed Central  Google Scholar 

  92. Flors L, Leiva-Salinas C, Maged IM, Norton PT, Matsumoto AH, Angle JF, et al. MR imaging of soft-tissue vascular malformations: diagnosis, classification, and therapy follow-up. Radiographics. 2011;31(5):1321–40.

    Article  PubMed  Google Scholar 

  93. Darrow DH. Management of infantile hemangiomas of the airway. Otolaryngol Clin North Am. 2018;51(1):133–46.

    Article  PubMed  Google Scholar 

  94. Fortes HR, Ranke FMV, Escuissato DL, Araujo Neto CA, Zanetti G, Hochhegger B, et al. Laryngotracheobronchial papillomatosis: chest CT findings. J Bras Pneumol. 2017;43(4):259–63. [Article in English, Portuguese].

    Article  PubMed  PubMed Central  Google Scholar 

  95. Fortes HR, von Ranke FM, Escuissato DL, Araujo Neto CA, Zanetti G, et al. Recurrent respiratory papillomatosis: a state-of-the-art review. Respir Med. 2017;126:116–21.

    Article  PubMed  Google Scholar 

  96. Fortman BJ, Kuszyk BS, Urban BA, Fishman EK. Neurofibromatosis type 1: a diagnostic mimicker at CT. Radiographics. 2001;21(3):601–12.

    Article  CAS  PubMed  Google Scholar 

  97. Meredith HC, Valicenti JF. Solitary neurofibroma of the trachea. Br J Radiol. 1978;51(603):218–9.

    Article  CAS  PubMed  Google Scholar 

  98. Kami YN, Chikui T, Okamura K, Kubota Y, Oobu K, Yabuuchi H, et al. Imaging findings of neurogenic tumours in the head and neck region. Dentomaxillofacial Radiol. 2012;41:18–23.

    Article  CAS  Google Scholar 

  99. Reviron-Rabec L, Girerd B, Seferian A, Campbell K, Brosseau S, Bergot E, et al. Pulmonary complications of type 1 neurofibromatosis. Rev Mal Respir. 2016;33(6):460–73.

    Article  CAS  PubMed  Google Scholar 

  100. Pappo AS, Meza JL, Donaldson SS, Wharam MD, Wiener ES, Qualman SJ, et al. Treatment of localized nonorbital, nonparameningeal head and neck rhabdomyosarcoma: lessons learned from intergroup rhabdomyosarcoma studies III and IV. J Clin Oncol. 2003;21(4):638–45.

    Article  PubMed  Google Scholar 

  101. Weiss AR, Lyden ER, Anderson JR, Hawkins DS, Spunt SL, Walterhouse DO, et al. Histologic and clinical characteristics can guide staging evaluations for children and adolescents with rhabdomyosarcoma: a report from the Children’s Oncology Group Soft Tissue Sarcoma Committee. J Clin Oncol. 2013;31(26):3226–32.

    Article  PubMed  PubMed Central  Google Scholar 

  102. Tröbs RB, Mader E, Friedrich T, Bennek J. Oral tumors and tumor-like lesions in infants and children. Pediatr Surg Int. 2003;19(9–10):639–45.

    Article  PubMed  Google Scholar 

  103. Friedman ER, John SD. Imaging of pediatric neck masses. Radiol Clin North Am. 2011;49(4):617–32.

    Article  PubMed  Google Scholar 

  104. Tranvinh E, Yeom KW, Iv M. Imaging neck masses in the neonate and young infant. Semin Ultrasound CT MRI. 2015;36(2):120–37.

    Article  Google Scholar 

  105. LaPlante JK, Pierson NS, Hedlund GL. Common pediatric head and neck congenital/developmental anomalies. Radiol Clin North Am. 2015;53(1):181–96.

    Article  PubMed  Google Scholar 

  106. Jeung M-Y, Gasser B, Gangi A, et al. Bronchial carcinoid tumors of the thorax: spectrum of radiologic findings. Radiographics. 2002;22(2):351–65.

    Article  PubMed  Google Scholar 

  107. Fauroux B, Aynie V, Larroquet M, Boccon-Gibod L, Ducou le Pointe H, Tamalet A, Clément A. Carcinoid and mucoepidermoid bronchial tumours in children. Eur J Pediatr. 2005;164(12):748–52.

    Article  PubMed  Google Scholar 

  108. Doppman JL, Pass HI, Nieman LK, Findling JW, Dwyer AJ, Feuerstein IM, et al. Detection of ACTH-producing bronchial carcinoid tumors: MR imaging vs CT. AJR Am J Roentgenol. 1991;156(1):39–43.

    Article  CAS  PubMed  Google Scholar 

  109. Amini B, Huang SY, Tsai J, Benveniste MF, Robledo HH, Lee EY. Primary lung and large airway neoplasms in children: current imaging evaluation with multidetector computed tomography. Radiol Clin North Am. 2013;51(4):637–57.

    Article  PubMed  Google Scholar 

  110. Baxi AJ, Chintapalli K, Katkar A, Restrepo CS, Betancourt SL, Sunnapwar A. Multimodality imaging findings in carcinoid tumors: a head-to-toe spectrum. Radiographics. 2017;37(2):516–36.

    Article  PubMed  Google Scholar 

  111. ElNayal A, Moran CA, Fox PS, Mawlawi O, Swisher SG, Marom EM. Primary salivary gland–type lung cancer: imaging and clinical predictors of outcome. AJR Am J Roentgenol. 2013;201(1):W57–63.

    Article  PubMed  PubMed Central  Google Scholar 

  112. Gaissert HA, Grillo HC, Shadmehr MB, Wright CD, Gokhale M, Wain JC, Mathisen DJ. Uncommon primary tracheal tumors. Ann Thorac Surg. 2006;82(1):268–73.

    Article  PubMed  Google Scholar 

  113. Butrynski JE, D’Adamo DR, Hornick JL, Dal Cin P, Antonescu CR, Jhanwar SC, et al. Crizotinib in ALK-rearranged inflammatory myofibroblastic tumor. N Engl J Med. 2010;363(18):1727–33.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  114. Lee EY, Greenberg SB, Boiselle PM. Multidetector computed tomography of pediatric large airway diseases: state-of-the-art. Radiol Clin North Am. 2011;49(5):869–93.

    Article  PubMed  Google Scholar 

  115. Semple T, Calder A, Owens CM, Padley S. Current and future approaches to large airways imaging in adults and children. Clin Radiol. 2017;72(5):356–74.

    Article  CAS  PubMed  Google Scholar 

  116. Kiryu T, Hoshi H, Matsui E, Iwata H, Kokubo M, Shimokawa K, Kawaguchi S. Endotracheal/endobronchial metastases : clinicopathologic study with special reference to developmental modes. Chest. 2001;119(3):768–75.

    Article  CAS  PubMed  Google Scholar 

  117. Downing GJ, Kilbride HW. Evaluation of airway complications in high-risk preterm infants: application of flexible fiberoptic airway endoscopy. Pediatrics. 1995;95(4):567–72.

    CAS  PubMed  Google Scholar 

  118. Gaebler C, Mueller M, Schramm W, Eckersberger F, Vécsei V. Tracheobronchial ruptures in children. Am J Emerg Med. 1996;14(3):279–84.

    Article  CAS  PubMed  Google Scholar 

  119. Kiyan G, Gocmen B, Tugtepe H, Karakoc F, Dagli E, Dagli TE. Foreign body aspiration in children: the value of diagnostic criteria. Int J Pediatr Otorhinolaryngol. 2009;73(7):963–7.

    Article  PubMed  Google Scholar 

  120. Hunter TB, Taljanovic MS. Foreign bodies. Radiographics. 2003;23(3):731–57. Review.

    Article  PubMed  Google Scholar 

  121. Bhat V, Bhat V, Salins P. Imaging spectrum of hemangioma and vascular malformations of the head and neck in children and adolescents. J Clin Imaging Sci. 2014;4:31. https://doi.org/10.4103/2156-7514.135179.

    Article  PubMed  PubMed Central  Google Scholar 

  122. Talat N, Belgaumkar AP, Schulte KM. Surgery in Castlemanʼs disease: a systematic review of 404 published cases. Ann Surg. 2012;255(4):677–84.

    Article  PubMed  Google Scholar 

  123. Madan R, Chen J, Trotman-Dickenson B, Jacobson F, Hunsaker A. The spectrum of Castleman’s disease: mimics, radiologic pathologic correlation and role of imaging in patient management. Eur J Radiol. 2012;81(1):123–31.

    Article  PubMed  Google Scholar 

  124. Tomolonis JA, Agarwal S, Shohet JM. Neuroblastoma pathogenesis: deregulation of embryonic neural crest development. Cell Tissue Res. 2018;372(2):245–62.

    Article  CAS  PubMed  Google Scholar 

  125. Brisse HJ, McCarville MB, Granata C, Krug KB, Wootton-Gorges SL, Kanegawa K, et al.; International Neuroblastoma Risk Group Project. Guidelines for imaging and staging of neuroblastic tumors: consensus report from the International Neuroblastoma Risk Group Project. Radiology. 2011;261(1):243–57.

    Article  Google Scholar 

  126. Swift CC, Eklund MJ, Kraveka JM, Alazraki AL. Updates in diagnosis, management, and treatment of neuroblastoma. Radiographics. 2018;38(2):566–80.

    Article  PubMed  Google Scholar 

  127. Golden CB, Feusner JH. Malignant abdominal masses in children: quick guide to evaluation and diagnosis. Pediatr Clin North Am. 2002;49(6):1369–92.

    Article  PubMed  Google Scholar 

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Ciet, P., Liszewski, M.C., Lee, E.Y. (2020). Large Airways. In: Lee, E., Liszewski, M., Gee, M., Daltro, P., Restrepo, R. (eds) Pediatric Body MRI. Springer, Cham. https://doi.org/10.1007/978-3-030-31989-2_2

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