Abstract
We propose an AutoML approach for the prediction of fluid intelligence from T1-weighted magnetic resonance images. We extracted 122 features from MRI scans and employed Sequential Model-based Algorithm Configuration to search for the best prediction pipeline, including the best data pre-processing and regression model. In total, we evaluated over 2600 prediction pipelines. We studied our final model by employing results from game theory in the form of Shapley values. Results indicate that predicting fluid intelligence from volume measurements is a challenging task with many challenges. We found that our final ensemble of 50 prediction pipelines associated larger parahippocampal gyrus volumes with lower fluid intelligence, and higher pons white matter volume with higher fluid intelligence.
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Barreiro, E., Munteanu, C.R., Cruz-Monteagudo, M., Pazos, A., González-Díaz, H.: Net-net auto machine learning (AutoML) prediction of complex ecosystems. Sci. Rep. 8(1), 12340 (2018)
Caruana, R., Niculescu-Mizil, A.: Ensemble selection from libraries of models. In: Proceedings of the 21st International Conference on Machine Learning, p. 18 (2004)
Feurer, M., Klein, A., Eggensperger, K., Springenberg, J., Blum, M., Hutter, F.: Efficient and robust automated machine learning. In: Advances in Neural Information Processing Systems 28, pp. 2962–2970 (2015)
Geurts, P., Ernst, D., Wehenkel, L.: Extremely randomized trees. Mach. Learn. 63(1), 3–42 (2006)
Guyon, I., et al.: Analysis of the AutoML challenge series 2015–2018. In: Hutter, F., Kotthoff, L., Vanschoren, J. (eds.) Automated Machine Learning. TSSCML, pp. 177–219. Springer, Cham (2019). https://doi.org/10.1007/978-3-030-05318-5_10
Hutter, F., Hoos, H.H., Leyton-Brown, K.: Sequential model-based optimization for general algorithm configuration. In: Coello, C.A.C. (ed.) LION 2011. LNCS, vol. 6683, pp. 507–523. Springer, Heidelberg (2011). https://doi.org/10.1007/978-3-642-25566-3_40
Le, T.T., Fu, W., Moore, J.H.: Scaling tree-based automated machine learning to biomedical big data with a feature set selector. Bioinformatics, 1–7 (2019)
Lipovetsky, S., Conklin, M.: Analysis of regression in game theory approach. Appl. Stoch. Models Bus. Ind. 17(4), 319–330 (2001)
Lundberg, S.M., Lee, S.I.: A unified approach to interpreting model predictions. In: Advances in Neural Information Processing Systems 30, pp. 4765–4774 (2017)
Orlenko, A., et al.: Considerations for automated machine learning in clinical metabolic profiling: altered homocysteine plasma concentration associated wtih metformin exposure. In: Pacific Symposium on Biocomputing, vol. 23. World Scientific (2017)
Pearson, K.: On lines and planes of closest fit to systems of points in space. Lond. Edinburgh Dublin Philos. Mag. J. Sci. 2(11), 559–572 (1901)
Pedregosa, F., et al.: Scikit-learn: machine learning in python. J. Mach. Learn. Res. 12, 2825–2830 (2011)
Pfefferbaum, A., et al.: Altered brain developmental trajectories in adolescents after initiating drinking. Am. J. Psychiatry 175(4), 370–380 (2018)
Puri, M.: Automated machine learning diagnostic support system as a computational biomarker for detecting drug-induced liver injury patterns in whole slide liver pathology images. Assay Drug Dev. Technol. (2019)
Rohlfing, T., Zahr, N.M., Sullivan, E.V., Pfefferbaum, A.: The SRI24 multichannel atlas of normal adult human brain structure. Hum. Brain Mapp. 31(5), 798–819 (2010)
Shapley, L.S.: A value for n-person games. Contrib. Theory Games 2(28), 307–317 (1953)
Štrumbelj, E., Kononenko, I.: Explaining prediction models and individual predictions with feature contributions. Knowl. Inf. Syst. 41(3), 647–665 (2014)
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This research was partially supported by the Bavarian State Ministry of Education, Science and the Arts in the framework of the Centre Digitisation.Bavaria (ZD.B).
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Pölsterl, S., Gutiérrez-Becker, B., Sarasua, I., Guha Roy, A., Wachinger, C. (2019). An AutoML Approach for the Prediction of Fluid Intelligence from MRI-Derived Features. In: Pohl, K., Thompson, W., Adeli, E., Linguraru, M. (eds) Adolescent Brain Cognitive Development Neurocognitive Prediction. ABCD-NP 2019. Lecture Notes in Computer Science(), vol 11791. Springer, Cham. https://doi.org/10.1007/978-3-030-31901-4_12
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