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Rectal and Vaginal Drug Delivery

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Part of the book series: AAPS Introductions in the Pharmaceutical Sciences ((AAPSINSTR))

Abstract

This chapter provides an overview of dosage forms relevant to rectal and vaginal drug delivery. Barriers to drug absorption are discussed and frequently used excipients are covered. The manufacturing and special formulation considerations for drug delivery using suppository formulations are also reviewed.

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Further Reading

  1. Suggested readings for the student include the following texts:

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  2. Lang B, McGinity JW, Williams RO. Hot melt extrusion—basic principles and pharmaceutical applications. Drug Dev Ind Pharm. 2014;40(9):1133–55.. (see page 1150; “Implants” section)

    Article  CAS  Google Scholar 

  3. Shin S, Byun S. Controlled release of ethinylestradiol from ethylene-vinyl acetate membrane. Int J Pharm. 1996;137(21):95–102.

    Article  CAS  Google Scholar 

  4. Anderson GD, Saneto RP. Current oral and non-oral routes of antiepileptic drug delivery. Adv Drug Deliv Rev. 2012;64(10):911–8.

    Article  CAS  Google Scholar 

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© 2019 American Association of Pharmaceutical Scientists

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Brunaugh, A.D., Smyth, H.D.C., Williams III, R.O. (2019). Rectal and Vaginal Drug Delivery. In: Essential Pharmaceutics. AAPS Introductions in the Pharmaceutical Sciences. Springer, Cham. https://doi.org/10.1007/978-3-030-31745-4_10

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