Abstract
Approaches to using optical coherence tomography (OCT) for ocular hemodynamics monitoring in patients with primary open angle glaucoma (POAG) are presented. The existing OCT systems used in ophthalmology are described. The different OCT systems are compared in accuracy and resolution characteristics, as these are important for clinical studies. The results of ocular hemodynamics monitoring of POAG patients using Spectralis OCT2 with an OCT Angiography module are given.
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Morizane, Y., Morimoto, N., Fujiwara, A., et al.: Incidence and causes of visual impairment in Japan: the first nation-wide complete enumeration survey of newly certified visually impaired individuals. Jpn. J. Ophthalmol. 63(1), 26–33 (2019)
Quigley, H.A.: Glaucoma: macrocosm to microcosm, the Frieden wald lecture. Invest. Ophthalmol. Vis. Sci. 46, 2662–2670 (2005)
Fechtner, R.D., Weinreb, R.N.: Mechanisms of optic nerve damage in primary open angle glaucoma. Surv. Ophthalmol. 39(1), 23–42 (1994)
Schmetterer, L.: Ocular Blood Flow, pp. 147–159. Springer, New York (2012)
Lieb, W.E.: Color Doppler ultrasonography of the eye and orbit. CurrentOpin. Ophthalmol. 4, 68–75 (1993)
Flammer, J., Orgul, S., Costa, V.P., et al.: The impact of ocular blood flow in glaucoma. Prog. Retin. Eye Res. 21, 359–393 (2002)
Kiseleva, T.N., Kotelin, V.I., Losanova, O.A., Lugovkina, K.V.: Noninvasive methods assessment blood flow in anterior segment and clinical application perspective. Oftalmologiya 15(4), 283–290 (2017). https://doi.org/10.18008/1816-5095-2017-4-283-290
Straubhaar, M., Orgul, S., Gugleta, K., et al.: Choroidal laser Doppler flowmetry in healthy subjects. Arch. Ophthalmol. 118(2), 211–215 (2000)
Kurysheva, N.I., Parshunina, O.A., Shatalova, E.O., et al.: Value of structural and hemodynamic parameters for the early detection of primary open-angle glaucoma. Curr. Eye Res. 42(3), 411–417 (2017)
Weinreb, R., Harris, A.: Ocular Blood Flow in Glaucoma: The 6th Consensus Report of the World Glaucoma Association, pp. 1–159. Kugler Publications, Amsterdam (2009)
Liu, L., Jia, Y., Takusagawa, H.L., et al.: Optical coherence tomography angiography of the peripapillary retina in glaucoma. JAMA Ophthalmol. 133(9), 1045 (2015)
Kurysheva, N.I., Maslova, E.V.: Optical coherence tomography angiography in glaucoma diagnosis. Vestn. oftalmol. 132(5), 98–102 (2016)
Popescu, D.P., Choo-Smith, L.-P., Flueraru, C., Mao, Y., Chang, S., Disano, J., Sowa, M.G.: Optical coherence tomography: fundamental principles, instrumental designs and biomedical applications. Biophys. Rev. 3(3), 155–169 (2011)
Grulkpwski, I., et al.: Scanning protocols dedicated to smart velocity ranging in Spectral OCT. Opt. Express 17, 23736–23754 (2009)
Hendargo, H.C., McNabb, R.P., Dhalla, A.H., Shepherd, N., Izatt, J.A.: Doppler velocity detection limitations in spectrometer – based versus swept – source optical coherence tomography. Biomed. Opt. Express 2, 2175–2188 (2011)
Wang, R.K., et al.: Three dimensional optical angiography. Opt. Express 15, 4083–4097 (2007)
Motaghiannezam, R., Fraser, S.: Logarithmic intensity and speacle – based motion contrast methods for human retinal vasculature visualization using swept source optical coherence tomography. Biomed. Opt. Express 3, 503–521 (2012)
Jia, Y., et al.: Split – spectrum amplitude – decorrelation angiography with optical coherence tomography. Opt. Express 20, 4710–4725 (2012)
Tokayer, J., Jia, Y., Dhalla, A.H., Huang, D.: Blood flow velocity quantification using split – spectrum amplitude decorrelation angiography with optical coherence tomography. Biomed. Opt. Express 4, 1909–1924 (2013)
Margolis, R., Spaide, R.F.: A pilot study of enhanced depth imaging optical coherence tomography of the choroid in normal eyes. Am. J. Ophthalmol. 147(5), 811–815 (2009)
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The authors declare that they have no conflict of interest. The paper was supported by a grant from RFBR (No. 18-08-01192).
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Iomdina, E.N., Khoziev, D.D., Kiseleva, A.A., Luzhnov, P.V., Kiseleva, O.A., Shamaev, D.M. (2020). Potentials of OCT in Monitoring Ocular Hemodynamics of Patients with Primary Open Angle Glaucoma. In: Henriques, J., Neves, N., de Carvalho, P. (eds) XV Mediterranean Conference on Medical and Biological Engineering and Computing – MEDICON 2019. MEDICON 2019. IFMBE Proceedings, vol 76. Springer, Cham. https://doi.org/10.1007/978-3-030-31635-8_47
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DOI: https://doi.org/10.1007/978-3-030-31635-8_47
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