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Precision in Pulmonary, Critical Care, and Sleep Medicine pp 25–37Cite as

Genetics and Pharmacogenetics of Asthma

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Part of the book series: Respiratory Medicine ((RM))

Abstract

Asthma and asthma-related traits, including response to bronchodilator and glucocorticoid drugs, are heritable traits. Our understanding of asthma genetics and pharmacogenetics has increased with the advent of high-throughput genomic techniques that have led to the discovery of loci linked to pathobiological mechanisms underlying asthma and its related traits and uncovered new targets for drug development. Although genomic findings have not yet changed clinical practice, translation of major insights may soon lead to increased asthma precision medicine.

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Authors and Affiliations

  1. Department of Biostatistics, Epidemiology and Informatics, University of Pennsylvania, Philadelphia, PA, USA

    Mengyuan Kan & Blanca E. Himes

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  1. Mengyuan Kan
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  2. Blanca E. Himes
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Correspondence to Blanca E. Himes .

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Editors and Affiliations

  1. Assistant Professor Pulmonary, Critical Care and Sleep Medicine Section, Department of Medicine, Yale University School of Medicine, New Haven, CT, USA

    Jose L. Gomez

  2. Assistant Professor of Informatics, Department of Biostatistics, Epidemiology and Informatics, University of Pennsylvania, Philadelphia, PA, USA

    Blanca E. Himes

  3. Boehringer-Ingelheim Endowed, Professor of Internal Medicine, Chief of Pulmonary, Critical Care and Sleep Medicine, Yale University School of Medicine, New Haven, CT, USA

    Naftali Kaminski

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Kan, M., Himes, B.E. (2020). Genetics and Pharmacogenetics of Asthma. In: Gomez, J., Himes, B., Kaminski, N. (eds) Precision in Pulmonary, Critical Care, and Sleep Medicine. Respiratory Medicine. Humana, Cham. https://doi.org/10.1007/978-3-030-31507-8_3

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  • DOI: https://doi.org/10.1007/978-3-030-31507-8_3

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  • Publisher Name: Humana, Cham

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  • Online ISBN: 978-3-030-31507-8

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