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Multiple-Disease Risk Predictive Modeling Based on Directed Disease Networks

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Abstract

This paper studies multiple-disease risk predictive models to assess a discharged patient’s future disease risks. We propose a novel framework that combines directed disease networks and recommendation system techniques to substantially enhance the performance of multiple-disease risk predictive modeling . Firstly, a directed disease network considering patients’ temporal information is developed. Then based on this directed disease network, we investigate different disease risk score computing approaches. We validate the proposed approaches using a hospital’s dataset. Promisingly, the predictive results can be well referenced by healthcare professionals who provide healthcare guidance for patients ready for discharge.

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Acknowledgements

A significant part of this work from Tingyan Wang and Robin Qiu was done with the support from the Big Data Lab at Penn State. This project was partially supported by IBM Faculty Awards (RDP-Qiu2016 and RDP-Qiu2017).

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Correspondence to Robin G. Qiu .

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Wang, T., Qiu, R.G., Yu, M. (2020). Multiple-Disease Risk Predictive Modeling Based on Directed Disease Networks. In: Yang, H., Qiu, R., Chen, W. (eds) Smart Service Systems, Operations Management, and Analytics. INFORMS-CSS 2019. Springer Proceedings in Business and Economics. Springer, Cham. https://doi.org/10.1007/978-3-030-30967-1_21

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