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Gold Nanoparticles in Diagnosis and Treatment of Alzheimer’s Disease

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Nanobiotechnology in Neurodegenerative Diseases

Abstract

Gold nanoparticles are one of the most important nanoparticles with many applications in diagnosis such as tumor markers detection, microbial pathogen detection, and many imaging techniques and therapies like gene therapy, cancer therapy, and drug delivery systems. Apart from this, these are also used in information technology and many electronic and communication technologies. Delivering of drug across the blood brain is a major problem in the neurodegenerative diseases majorly Parkinson and Alzheimer’s diseases. The gold nanoparticles are golden opportunities in the treatment of neurodegenerative diseases and drug delivery in the blood-brain barriers and inducing the neuronal activities. This chapter clearly explains about the gold nanoparticles and its very clear applications in the blood-brain barrier hurdle to treat neurodegenerative diseases, biomarkers for Alzheimer’s disease, diagnostics targeting, and inhibiting amyloid fibrils in AD and role of gold nanoparticles in the Alzheimer’s disease treatment.

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Authors and Affiliations

  1. Department of Research and Development, Saveetha Institute of Medical and Technical Sciences (SIMATS), Chennai, Tamil Nadu, India

    Senthilkumar Sivanesan

  2. Nanomedicine Laboratory, Department of Pharmacology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences (SIMATS), Chennai, Tamil Nadu, India

    Shanmugam Rajeshkumar

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  1. Senthilkumar Sivanesan
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  2. Shanmugam Rajeshkumar
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Editors and Affiliations

  1. Nanobiotechnology Laboratory, Department of Biotechnology, SGB Amravati University, Amravati, Maharashtra, India, Department of Chemistry, Federal University of Piauí, Teresina, Piauí, Brazil

    Mahendra Rai

  2. Nanobiotechnology Laboratory, Department of Biotechnology, SGB Amravati University, Amravati, Maharashtra, India

    Alka Yadav

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Sivanesan, S., Rajeshkumar, S. (2019). Gold Nanoparticles in Diagnosis and Treatment of Alzheimer’s Disease. In: Rai, M., Yadav, A. (eds) Nanobiotechnology in Neurodegenerative Diseases. Springer, Cham. https://doi.org/10.1007/978-3-030-30930-5_12

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