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Soft Tissue and Bone Sarcomas

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Occupational Cancers

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Abstract

Sarcomas are a heterogeneous group of relatively rare neoplasms. The only established risk factors of soft tissue sarcomas, which represent 80% of all sarcomas, are ionizing radiation and alkylating agents used in chemotherapy. Extensive research on a possible etiologic role of dioxin, chlorophenoxy herbicides, and chlorophenols has not provided definite evidence of a causal association. A part from an effect of high-level exposure to ionizing radiation detected in historical studies of radiologists and radium-exposed workers, no occupational risk factors have been identified for bone sarcoma.

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Authors and Affiliations

  1. Humanitas Gradenigo Hospital, Turin, Italy

    Alessandro Comandone

  2. Department of Public Health and Pediatric Sciences, University of Turin, Turin, Italy

    Giacomo Garzaro & Enrico Pira

  3. Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA

    Paolo Boffetta

  4. Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy

    Paolo Boffetta

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  1. Alessandro Comandone
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  2. Giacomo Garzaro
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  3. Enrico Pira
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  4. Paolo Boffetta
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Correspondence to Paolo Boffetta .

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Editors and Affiliations

  1. Department of Pathology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland

    Sisko Anttila

  2. Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA

    Paolo Boffetta

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Comandone, A., Garzaro, G., Pira, E., Boffetta, P. (2020). Soft Tissue and Bone Sarcomas. In: Anttila, S., Boffetta, P. (eds) Occupational Cancers. Springer, Cham. https://doi.org/10.1007/978-3-030-30766-0_22

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