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Investigating the Use of Wearables for Monitoring Circadian Rhythms: A Feasibility Study

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Future Trends in Biomedical and Health Informatics and Cybersecurity in Medical Devices (ICBHI 2019)

Abstract

Circadian rhythms are physiological and behavioural processes that typically recur over 24-h periods.

Researchers show that circadian disruption, a marked break in normal 24-h cycles of circadian rhythms, can cause serious health problems. It could lead to critical illness, cancer, stress, myocardial infarction, diabetes, hypertension and arrhythmias.

Today, circadian rhythms are monitored using blood, salivary and urine hormone tests, such tests are not practical at home and do not provide continuous real-time monitoring. Combining signal processing and artificial intelligence with commercial sensors embedded in smartwatches or clothes that measure physiological and behavioral attributes offers unprecedented and as yet unexplored opportunities to monitor circadian rhythms in real time. This paper presents the initial steps towards the development of a model for real-time monitoring of the circadian rhythms. This model will contribute to transform medicine from primarily intervention-focused to predictive and preventative. Preliminary analysis shows promising results to automatically classify cortisol levels as high or low, based on behavioral and physiological signals monitored by non-invasive wearable sensors.

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References

  1. Van Laake, L.W., Lüscher, T.F., Young, M.E.: The circadian clock in cardiovascular regulation and disease: lessons from the nobel prize in physiology or medicine 2017. Eur. Heart J. 39, 2326–2329 (2017)

    Article  Google Scholar 

  2. Eckle, T.: Health impact and management of a disrupted circadian rhythm and sleep in critical illnesses. Curr. Pharm. Des. 21(24), 3428 (2015)

    Article  Google Scholar 

  3. Lévi, F., Okyar, A., Dulong, S., Innominato, P.F., Clairambault, J.: Circadian timing in cancer treatments. Ann. Rev. Pharm. Toxicol. 50, 377–421 (2010)

    Article  Google Scholar 

  4. Smith, M.T., et al.: Use of actigraphy for the evaluation of sleep disorders and circadian rhythm sleep-wake disorders: an American Academy of Sleep Medicine clinical practice guideline. J. Clin. Sleep Med. 14(07), 1231–1237 (2018)

    Article  Google Scholar 

  5. Dorn, L.D., Lucke, J.F., Loucks, T.L., Berga, S.L.: Salivary cortisol reflects serum cortisol: analysis of circadian profiles. Ann. Clin. Biochem. 44(3), 281–284 (2007)

    Article  Google Scholar 

  6. Mormont, M., Levi, F.: Circadian-system alterations during cancer processes: a review. Int. J. Cancer 70(2), 241–247 (1997)

    Article  Google Scholar 

  7. Hasselberg, M.J., McMahon, J., Parker, K.: The validity, reliability, and utility of the iButton® for measurement of body temperature circadian rhythms in sleep/wake research. Sleep Med. 14(1), 5–11 (2013)

    Article  Google Scholar 

  8. de Assis, M.A.A., Kupek, E., Nahas, M.V., Bellisle, F.: Food intake and circadian rhythms in shift workers with a high workload. Appetite 40(2), 175–183 (2003)

    Article  Google Scholar 

  9. Buysse, D.J., Reynolds III, C.F., Monk, T.H., Hoch, C.C., Yeager, A.L., Kupfer, D.J.: Quantification of subjective sleep quality in healthy elderly men and women using the Pittsburgh Sleep Quality Index (PSQI). Sleep 14(4), 331–338 (1991)

    Google Scholar 

  10. Carney, C.E., et al.: The consensus sleep diary: standardizing prospective sleep self-monitoring. Sleep 35(2), 287–302 (2012)

    Article  Google Scholar 

  11. Budde, H., Machado, S., Ribeiro, P., Wegner, M.: The cortisol response to exercise in young adults. Front. Behav. Neurosci. 9, 13 (2015)

    Article  Google Scholar 

  12. Goldberger, A.L., et al.: Physiobank, physiotoolkit, and physionet components of a new research resource for complex physiologic signals. Circulation 101(23), e215–e220 (2000)

    Article  Google Scholar 

  13. Tarvainen, M.P., Niskanen, J.-P.: Kubios HRV user’s guide. In: Biosignal Analysis and Medical Imaging Group (BSAMIG), Department of Physics University of Kuopio (2013)

    Google Scholar 

  14. Force, T.: Heart rate variability guidelines: Standards of measurement, physiological interpretation, and clinical use. Eur. Heart J. 17, 354–381 (1996)

    Article  Google Scholar 

  15. Melillo, P., Bracale, M., Pecchia, L.: Nonlinear heart rate variability features for real-life stress detection. Case study: students under stress due to university examination (in English). BioMed. Eng. OnLine 10(1), 1–13 (2011). Article no. 96

    Article  Google Scholar 

  16. Castaldo, R., Melillo, P., Izzo, R., Luca, N.D., Pecchia, L.: Fall prediction in hypertensive patients via short-term HRV analysis. IEEE J. Biomed. Health Inf. 21(2), 399–406 (2017)

    Article  Google Scholar 

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Acknowledgment

We acknowledge the EPSRC-funded grant under the Cyclops Healthcare Network. RC thanks the Institute of Advanced studies at the University of Warwick.

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Correspondence to Rossana Castaldo .

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Castaldo, R. et al. (2020). Investigating the Use of Wearables for Monitoring Circadian Rhythms: A Feasibility Study. In: Lin, KP., Magjarevic, R., de Carvalho, P. (eds) Future Trends in Biomedical and Health Informatics and Cybersecurity in Medical Devices. ICBHI 2019. IFMBE Proceedings, vol 74. Springer, Cham. https://doi.org/10.1007/978-3-030-30636-6_38

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  • DOI: https://doi.org/10.1007/978-3-030-30636-6_38

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  • Print ISBN: 978-3-030-30635-9

  • Online ISBN: 978-3-030-30636-6

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