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Bioactive Metabolites from Marine Ascidians: Future Treatment for Autism Spectrum Disorder

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Personalized Food Intervention and Therapy for Autism Spectrum Disorder Management

Part of the book series: Advances in Neurobiology ((NEUROBIOL,volume 24))

Abstract

Autism spectrum disorder (ASD) is a developmental disorder that influences communication and behavior. Numerous researches propose that genes can act together with manipulations from the environment to affect development in ways that lead to ASD. The broad range of issues facing people with ASD means that there is no single proper drug and treatment for ASD. Numerous shortcomings associated with the present conventional therapeutic strategies have forced researchers to venture into alternative natural sources for effective compounds. The marine environment has emerged as an alternate search environment due to its versatile conditions where organisms employ various biodefense mechanisms for their survival. Ascidians are an excellent source for unique bioactive compounds with nutritive and therapeutic content and it still holds credit for being an underused source from marine animals. Bioactive compounds isolated from ascidians have various commendable biomedical applications due to their unique chemical structures. The present chapter will focus on the potential of bioactive compounds derived from ascidians for the treatment of the neurologic disorder—ASD.

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Acknowledgments

The chapter was supported by the Science and Engineering Research Board, India under grant SB/YS/LS-374/2013, CSIR—SRF, UGC-FIST and UGC-SAP, New Delhi.

Competing Interests

Authors disclose no potential conflicts of interest.

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Authors and Affiliations

  1. Department of Medical Biotechnology, Chettinad Academy of Research and Education, Chennai, Tamil Nadu, India

    Manigandan Venkatesan, Nishakavya Saravanan & Saravanan Ramachandran

  2. Department of Environmental Biotechnology, School of Environmental Sciences, Bharathidasan University, Tiruchirappalli, Tamil Nadu, India

    Velusamy Arumugam & Umamaheswari Sundaresan

  3. Department of Animal Science, Centre for Pheromone Technology, Bharathidasan University, Tiruchirappalli, Tamil Nadu, India

    Rathinam Ayyasamy

  4. Department of Biotechnology, Anna University, Tiruchirappalli, Tamil Nadu, India

    Selvakumar Murugesan

  5. Department of Biochemistry and Biotechnology, Annamalai University, Chidambaram, Tamil Nadu, India

    Thamilarasan Manivasagam & Arokiasamy Justin Thenmozhi

  6. Research & Policy Department, World Innovation Summit for Health (WISH), Qatar Foundation, Doha, Qatar

    M. Walid Qoronfleh

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Editors and Affiliations

  1. Food Science and Nutrition, CAMS, Sultan Qaboos University, Muscat, Oman

    M. Mohamed Essa

  2. World Innovation Summit for Health WISH, Qatar Foundation, Doha, Qatar

    M. Walid Qoronfleh

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Venkatesan, M. et al. (2020). Bioactive Metabolites from Marine Ascidians: Future Treatment for Autism Spectrum Disorder. In: Essa, M., Qoronfleh, M. (eds) Personalized Food Intervention and Therapy for Autism Spectrum Disorder Management. Advances in Neurobiology, vol 24. Springer, Cham. https://doi.org/10.1007/978-3-030-30402-7_25

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