Skip to main content

MNAR Imputation with Distributed Healthcare Data

  • Conference paper
  • First Online:

Part of the book series: Lecture Notes in Computer Science ((LNAI,volume 11805))

Abstract

Missing data is a problem found in real-world datasets that has a considerable impact on the learning process of classifiers. Although extensive work has been done in this field, the MNAR mechanism still remains a challenge for the existing imputation methods, mainly because it is not related with any observed information. Focusing on healthcare contexts, MNAR is present in multiple scenarios such as clinical trials where the participants may be quitting the study for reasons related to the outcome that is being measured. This work proposes an approach that uses different sources of information from the same healthcare context to improve the imputation quality and classification performance for datasets with missing data under MNAR. The experiment was performed with several databases from the medical context and the results show that the use of multiple sources of data has a positive impact in the imputation error and classification performance.

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Notes

  1. 1.

    Available at https://pandas.pydata.org/.

  2. 2.

    Available at https://scikit-learn.org/stable/.

  3. 3.

    Available at https://github.com/iskandr/fancyimpute.

  4. 4.

    Available at https://archive.ics.uci.edu/ml/datasets.html.

  5. 5.

    Available at https://www.kaggle.com/.

  6. 6.

    Although the Nemenyi test p-values are two-tailed, it is possible to ensure that these results always reflect improvement in the F1 scores by cross-analyzing them with the ones from Table 4.

References

  1. Abreu, P.H., Amaro, H., Silva, D.C., Machado, P., Abreu, M.H.: Personalizing breast cancer patients with heterogeneous data. In: Zhang, Y.-T. (ed.) The International Conference on Health Informatics. IP, vol. 42, pp. 39–42. Springer, Cham (2014). https://doi.org/10.1007/978-3-319-03005-0_11

    Chapter  Google Scholar 

  2. Azur, M.J., Stuart, E.A., Frangakis, C., Leaf, P.J.: Multiple imputation by chained equations: what is it and how does it work? Int. J. Methods Psychiatr. Res. 20(1), 40–49 (2011)

    Article  Google Scholar 

  3. Baraldi, A.N., Enders, C.K.: An introduction to modern missing data analyses. J. Sch. Psychol. 48(1), 5–37 (2010)

    Article  Google Scholar 

  4. Costa, A.F., Santos, M.S., Soares, J.P., Abreu, P.H.: Missing data imputation via denoising autoencoders: the untold story. In: Duivesteijn, W., Siebes, A., Ukkonen, A. (eds.) IDA 2018. LNCS, vol. 11191, pp. 87–98. Springer, Cham (2018). https://doi.org/10.1007/978-3-030-01768-2_8

    Chapter  Google Scholar 

  5. Garciarena, U., Santana, R.: An extensive analysis of the interaction between missing data types, imputation methods, and supervised classifiers. Expert Syst. Appl. 89, 52–65 (2017)

    Article  Google Scholar 

  6. Hastie, T., Mazumder, R., Lee, J.D., Zadeh, R.: Matrix completion and low-rank SVD via fast alternating least squares. J. Mach. Learn. Res. 16(1), 3367–3402 (2015)

    MathSciNet  MATH  Google Scholar 

  7. van Kuijk, S.M., Viechtbauer, W., Peeters, L.L., Smits, L.: Bias in regression coefficient estimates when assumptions for handling missing data are violated: a simulation study. Epidemiol. Biostat. Public Health 13(1), e11598-1–e11598-8 (2016)

    Google Scholar 

  8. Olsen, I., Kvien, T., Uhlig, T.: Consequences of handling missing data for treatment response in osteoarthritis: a simulation study. Osteoarthritis Cartilage 20(8), 822–828 (2012)

    Article  Google Scholar 

  9. Santos, M.S., Abreu, P.H., García-Laencina, P.J., Simão, A., Carvalho, A.: A new cluster-based oversampling method for improving survival prediction of hepatocellular carcinoma patients. J. Biomed. Inform. 58, 49–59 (2015)

    Article  Google Scholar 

  10. Santos, M.S., Soares, J.P., Henriques Abreu, P., Araújo, H., Santos, J.: Influence of data distribution in missing data imputation. In: ten Teije, A., Popow, C., Holmes, J.H., Sacchi, L. (eds.) AIME 2017. LNCS (LNAI), vol. 10259, pp. 285–294. Springer, Cham (2017). https://doi.org/10.1007/978-3-319-59758-4_33

    Chapter  Google Scholar 

  11. Smola, A.J., Schölkopf, B.: A tutorial on support vector regression. Stat. Comput. 14(3), 199–222 (2004)

    Article  MathSciNet  Google Scholar 

  12. Valdiviezo, H.C., Van Aelst, S.: Tree-based prediction on incomplete data using imputation or surrogate decisions. Inf. Sci. 311, 163–181 (2015)

    Article  Google Scholar 

  13. Wolkowitz, A.A., Skorupski, W.P.: A method for imputing response options for missing data on multiple-choice assessments. Educ. Psychol. Measur. 73(6), 1036–1053 (2013)

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Ricardo Cardoso Pereira .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2019 Springer Nature Switzerland AG

About this paper

Check for updates. Verify currency and authenticity via CrossMark

Cite this paper

Pereira, R.C., Santos, M.S., Rodrigues, P.P., Abreu, P.H. (2019). MNAR Imputation with Distributed Healthcare Data. In: Moura Oliveira, P., Novais, P., Reis, L. (eds) Progress in Artificial Intelligence. EPIA 2019. Lecture Notes in Computer Science(), vol 11805. Springer, Cham. https://doi.org/10.1007/978-3-030-30244-3_16

Download citation

  • DOI: https://doi.org/10.1007/978-3-030-30244-3_16

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-30243-6

  • Online ISBN: 978-3-030-30244-3

  • eBook Packages: Computer ScienceComputer Science (R0)

Publish with us

Policies and ethics