Diagnostic Adjuncts for Screening and Surveillance in Head and Neck Cancer

  • James MurphyEmail author
  • Mohammed Qaisi


Head and neck cancers tend to be diagnosed at a late stage. This has prognostic implications for the patient. Research interest has been directed to developing diagnostic and screening adjuncts that would facilitate earlier diagnosis of this condition. Adjuncts include vital staining, visual light-based adjuncts, exfoliative-based techniques, molecular biology, and in vivo microscopy. These will be discussed in this chapter. Although these techniques have not been shown to be as effective as a thorough clinical oral examination, they remain as an area of interest and active research.


Toludine blue Lugol’s iodine Chemiluminescence Tissue fluorescence imaging Brush biopsy DNA-image cytometry Molecular biology In vivo microscopy 



The authors have no conflict of interest to declare.


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Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  1. 1.Division of Oral and Maxillofacial Surgery, Department of SurgeryJohn H. Stroger, Jr. Hospital of Cook CountyChicagoUSA

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