Abstract
Cancer is a major disease of cats in terms of health and welfare, and skin tumours in cats are the second most common tumour type, accounting for around 25% of all reported neoplasms (Argyle, Decision making in small animal oncology. Oxford: Blackwell/Wiley, 2008). Compared to dogs (who demonstrate significantly higher numbers of benign skin masses), around 65–70% of skin masses in cats are malignant. Occasionally tumours of the skin are actually metastatic lesions. The best example of this is the syndrome of digital and cutaneous metastasis associated with lung cancer in cats (less commonly seen in the dog) and is described in more detail below (Goldfinch and Argyle, J Feline Med Surg 14:202–8, 2012).
For many years, feline cancer medicine was dominated by virally induced lymphoma. While lymphoma is still a major problem in cats, the increase in vaccination has reduced the incidence of this disease and allowed other tumours to become prominent players, particularly squamous cell carcinoma (SCC), mast cell disease and vaccine-associated sarcomas. This chapter is designed to give the reader a broad understanding of the classification and approach to cancer in cats and a synopsis of the major tumour types.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Argyle DJ. Decision making in small animal oncology. Oxford: Blackwell/Wiley; 2008.
Goldfinch N, Argyle DJ. Feline lung-digit syndrome: unusual metastatic patterns of primary lung tumours in cats. J Feline Med Surg. 2012;14:202–8.
Sharif M. Epidemiology of skin tumor entities according to the new WHO classification in dogs and cats. VVB Laufersweiler: Giessen; 2006.
Argyle DJ, Blacking TM. From viruses to cancer stem cells: dissecting the pathways to malignancy. Vet J. 2008;177:311–23.
Sunberg JP, Van Ranst M, Montali R, et al. Feline papillomas and papillomaviruses. Vet Pathol. 2000;37:1–10.
Hanna PE, Dunn D. Cutaneous fibropapilloma in a cat (feline sarcoid). Can Vet J. 2003;44:601–2.
Backel K, Cain C. Skin as a marker of general feline health: cutaneous manifestations of infectious disease. J Feline Med Surg. 2017;19:1149–65.
Diters RW, Walsh KM. Feline basal cell tumors: a review of 124 cases. Vet Pathol. 1984;21:51–6.
Murphy S. Skin neoplasia in small animals 2. Common feline tumours. In Pract. 2006;28:320–5.
Peters-Kennedy J, Scott DW, Miller WH. Apparent clinical resolution of pinnal actinic keratoses and squamous cell carcinoma in a cat using topical imiquimod 5% cream. J Feline Med Surg. 2008;10:593–9.
Almeida EM, Caraca RA, Adam RL, et al. Photodamage in feline skin: clinical and histomorphometric analysis. Vet Pathol. 2008;45:327–35.
Murphy S. Cutaneous squamous cell carcinoma in the cat: current understanding and treatment approaches. J Feline Med Surg. 2013;15:401–7.
Cunha SC, Carvalho LA, Canary PC, et al. Radiation therapy for feline cutaneous squamous cell carcinoma using a hypofractionated protocol. J Feline Med Surg. 2010;12:306–13.
Tozon N, Pavlin D, Sersa G, et al. Electrochemotherapy with intravenous bleomycin injection: an observational study in superficial squamous cell carcinoma in cats. J Feline Med Surg. 2014;16:291–9.
Goodfellow M, Hayes A, Murphy S, Brearley M. A retrospective study of (90) Strontium plesiotherapy for feline squamous cell carcinoma of the nasal planum. J Feline Med Surg. 2006;8(3):169–176. https://doi.org/10.1016/j.jfms.2005.12.003.
Hammond GM, Gordon IK, Theon AP, Kent MS. Evaluation of strontium Sr 90 for the treatment of superficial squamous cell carcinoma of the nasal planum in cats: 49 cases (1990–2006). J Am Vet Med Assoc. 2007;231(5):736–741. https://doi.org/10.2460/javma.231.5.736.
Hartmann K, Day M, Thiry E, et al. Feline injection-site sarcoma: ABCD guidelines on prevention and management. J Feline Med Surg. 2015;17:606–13.
Rossi F, Marconato L, Sabattini S, et al. Comparison of definitive-intent finely fractionated and palliative-intent coarsely fractionated radiotherapy as adjuvant treatment of feline microscopic injection-site sarcoma. J Feline Med Surg. 2019;21:65–72.
Woods S, de Castro AI, Renwick MG, et al. Nanocrystalline silver dressing and subatmospheric pressure therapy following neoadjuvant radiation therapy and surgical excision of a feline injection site sarcoma. J Feline Med Surg. 2012;14:214–8.
Müller N, Kessler M. Curative-intent radical en bloc resection using a minimum of a 3 cm margin in feline injection-site sarcomas: a retrospective analysis of 131 cases. J Feline Med Surg. 2018;20:509–19.
Ladlow J. Injection site-associated sarcoma in the cat: treatment recommendations and results to date. J Feline Med Surg. 2013;15:409–18.
Litster AL, Sorenmo KU. Characterisation of the signalment, clinical and survival characteristics of 41 cats with mast cell neoplasia. J Feline Med Surg. 2006;8:177–83.
Henry C, Herrera C. Mast cell tumors in cats: clinical update and possible new treatment avenues. J Feline Med Surg. 2013;15:41–7.
Blackwood L, Murphy S, Buracco P, et al. European consensus document on the management of canine and feline mast cell disease. Vet Comp Oncol. 2012;10:e1–e29.
Fontaine J, Heimann M, Day MJ. Cutaneous epitheliotropic T-cell lymphoma in the cat: a review of the literature and five new cases. Vet Dermatol. 2011;22:454–61.
Gilbert S, Affolter VK, Gross TL, et al. Clinical, morphological and immunohistochemical characterization of cutnaeous lymphocytosis in 23 cats. Vet Dermatol. 2004;15:3–12.
Pariser MS, Gram DW. Feline cutaneous lymphocytosis: case report and summary of the literature. J Feline Med Surg. 2014;16(9):758–63.
Affolter VK, Moore PF. Feline progressive Histiocytosis. Vet Pathol. 2006;43:646–55.
Miller W, Griffin C, Campbell K. Muller & Kirk’s small animal dermatology. 7th ed. Elsevier Health Sciences: Missouri; 2013.
Chamel G, Abadie J, Albaric O, et al. Non-ocular melanomas in cats: a retrospective study of 30 cases. J Feline Med Surg. 2017;19:351–7.
London CA, Dubilzeig RR, Vail DM, et al. Evaluation of dogs and cats with tumors of the ear canal: 145 cases (1978-1992). J Am Vet Med Assoc. 1996;208:1413–8.
Hinrichs U, Puhl S, Rutteman GR, et al. Lymphangiosarcoma in cats: a retrospective study of 13 cases. Vet Pathol. 1999;36:164–7.
Colombo S, Fabbrini F, Corona A, et al. Linfocitosi cutanea felina: descrizione di tre casi clinici. Veterinaria (Cremona). 2011;25:25–31.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2020 Springer Nature Switzerland AG
About this chapter
Cite this chapter
Argyle, D.J., Bavčar, Š. (2020). Neoplastic Diseases. In: Noli, C., Colombo, S. (eds) Feline Dermatology. Springer, Cham. https://doi.org/10.1007/978-3-030-29836-4_30
Download citation
DOI: https://doi.org/10.1007/978-3-030-29836-4_30
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-030-29835-7
Online ISBN: 978-3-030-29836-4
eBook Packages: Biomedical and Life SciencesBiomedical and Life Sciences (R0)