Abstract
Ketones are acetone, acetoacetic acid (acetoacetate), and β-hydroxybutyric acid (BHB). Of these, only acetoacetate and BHB cause acidosis, whereas acetone does not cause acidosis. Acetone is formed by nonenzymatic decarboxylation of acetoacetate, and does not contribute any acid load to the body. Clinically, metabolic acidosis due to ketone overload is caused by diabetes, alcohol, and starvation. Therefore, this chapter focuses on only diabetic, alcoholic, and starvation ketoacidosis.
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Reddi, A.S. (2020). Ketoacidosis. In: Acid-Base Disorders. Springer, Cham. https://doi.org/10.1007/978-3-030-28895-2_6
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DOI: https://doi.org/10.1007/978-3-030-28895-2_6
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