Imaging in Melanoma



Imaging plays an important role in the management of patients with melanoma at presentation, staging, follow up and in monitoring the effects of new adjuvant therapies. Pre-operative lymphoscintigraphy accurately identifies sentinel nodes and radiolabels them for surgical removal aided by a gamma probe in sentinel node biopsy. Combined with targeted histopathology this has lifted regional lymph node staging to new levels of accuracy.

Ultrasound using high frequency probes can detect early nodal metastasis before any lump is palpable clinically and guides fine needle biopsy. It also can define the nature of any soft tissue lump that may appear on follow up in node fields or elsewhere.

Cross sectional imaging adds additional precision to the localisation of sentinel nodes aiding their surgical removal. It also plays an important role in upstaging melanoma patients with more advanced disease and in monitoring the effect of adjuvant therapy using anatomical and metabolic criteria.


Lymphoscintigraphy Sentinel node biopsy Ultrasound Metastasis Cross sectional imaging Upstaging Monitoring therapy 


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Copyright information

© Springer Nature Switzerland AG 2021

Authors and Affiliations

  1. 1.Alfred Nuclear Medicine and UltrasoundRPAH Medical CenterNewtownAustralia
  2. 2.Melanoma Institute AustraliaNorth SydneyAustralia
  3. 3.Sydney Medical SchoolThe University of SydneySydneyAustralia

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