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Improvement of Mass Transport at the Surface of an SPR Biosensor Applied in Microfluidics

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Design and Modeling of Mechanical Systems - IV (CMSM 2019)

Part of the book series: Lecture Notes in Mechanical Engineering ((LNME))

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Abstract

The main objective of this work is to improve particle transport in a sensitive membrane microchannel in order to reduce the detection time of the biosensor. This requires analyzing the effects to improve the performance of the biosensor. Using numerical simulations, we studied the effect of the application of a magnetic field on the kinetic response of the biosensor. Thus the coupling of diffusion convection phenomenon with the adsorption and desorption reaction of the molecules on the Surface Resonance Biosensor Surface (SPR). These simulations are based on Navier Stokes equations, mass transport equations, chemical kinetics equations, and magnetostatics equations. The results found show an improvement in the fluid velocity and subsequently the diffusion and convection mass transport at the biosensor surface.

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Author information

Authors and Affiliations

  1. Quantum and Statistical Physics Laboratory, Faculty of Science of Monastir, University of Monastir, Environment Boulevard, 5019, Monastir, Tunisia

    Yosra Saad & Mohamed Hichem Gazzah

  2. Department of Radiological Sciences and Imaging, Faculty of Applied Medical Sciences, Majmaah University, Al Majmaah, 11952, Saudi Arabia

    Marwa Selmi

  3. Laboratory of Electronics and Microelectronics, Faculty of Science of Monastir, University of Monastir, Monastir, Tunisia

    Marwa Selmi & Hafedh Belmabrouk

  4. Department of Physics, College of Science at AlZulfi, Majmaah University, Al Zulfi, 11932, Saudi Arabia

    Hafedh Belmabrouk

Authors
  1. Yosra Saad
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  2. Marwa Selmi
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  3. Mohamed Hichem Gazzah
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  4. Hafedh Belmabrouk
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Corresponding author

Correspondence to Yosra Saad .

Editor information

Editors and Affiliations

  1. Preparatory Institute of Engineering Studies of Monastir (IPEIM), Monastir, Tunisia

    Nizar Aifaoui

  2. National Engineering School of Monastir (ENIM), Monastir, Tunisia

    Zouhaier Affi

  3. National School of Engineers of Sfax (ENIS), Sfax, Tunisia

    Mohamed Slim Abbes

  4. National School of Engineers of Sfax (ENIS), Sfax, Tunisia

    Lassad Walha

  5. National School of Engineers of Sfax (ENIS), Sfax, Tunisia

    Mohamed Haddar

  6. National Engineering School of Sousse (ENISO), Sousse, Tunisia

    Lotfi Romdhane

  7. National Engineering School of Monastir (ENIM), Monastir, Tunisia

    Abdelmajid Benamara

  8. National Engineering School of Monastir (ENIM), Monastir, Tunisia

    Mnaouar Chouchane

  9. Department of Mechanical Engineering, National School of Engineers of Sfax (ENIS), Sfax, Tunisia

    Fakher Chaari

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Saad, Y., Selmi, M., Gazzah, M.H., Belmabrouk, H. (2020). Improvement of Mass Transport at the Surface of an SPR Biosensor Applied in Microfluidics. In: Aifaoui, N., et al. Design and Modeling of Mechanical Systems - IV. CMSM 2019. Lecture Notes in Mechanical Engineering. Springer, Cham. https://doi.org/10.1007/978-3-030-27146-6_16

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  • DOI: https://doi.org/10.1007/978-3-030-27146-6_16

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-27145-9

  • Online ISBN: 978-3-030-27146-6

  • eBook Packages: EngineeringEngineering (R0)

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