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A Detailed Design and Construction of a Supercritical Antisolvent Precipitation Equipment

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Abstract

This work consists of the steps for the assembly of a Supercritical Antisolvent Precipitation laboratory equipment and evaluation of the parts acquisition costs. A flow diagram with all components was developed, a complete list of all necessary components was presented, and an estimate of the acquisition of these parts in Brazil was reported. The stages of construction along with the importance of each component in the equipment were discussed. An equipment designs were presented as a result of the current work that serve as a basis for consulting future work on the development of new equipment.

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References

  1. G.L. Zabot, M.A.A. Meireles, On-line process for pressurized ethanol extraction of onion peels extract and particle formation using supercritical antisolvent. J. Supercrit. Fluids 110, 230–239 (2016). https://doi.org/10.1016/j.supflu.2015.11.024

    Article  CAS  Google Scholar 

  2. V. Prosapio, I. De Marco, E. Reverchon, Supercritical antisolvent coprecipitation mechanisms. J. Supercrit. Fluids 138, 247–258 (2018). https://doi.org/10.1016/j.supflu.2018.04.021

    Article  CAS  Google Scholar 

  3. Thar, Thar Technologies (2010), http://www.thartech.com. Accessed 16 July 2010

  4. G.B. Jacobson, R. Shinde, R.L. McCullough, N.J. Cheng, A. Creasman, A. Beyene, R.P. Hickerson, C. Quan, C. Turner, R.L. Kaspar, C.H. Contag, R.N. Zare, Nanoparticle formation of organic compounds with retained biological activity. J. Pharm. Sci. 99(6), 2750–2755 (2010). https://doi.org/10.1002/jps.22035

    Article  CAS  PubMed  Google Scholar 

  5. Extratex (2018) Supercritical fluid extract and particle formation system. (Extratex S.A.R.L. 2018), http://www.extratex-sfi.com/equipments/sas-ress-pgss. Accessed 26 June 2018

  6. J.C.F. Johner, MAdA MEIRELES, Construction of a supercritical fluid extraction (SFE) equipment: validation using annatto and fennel and extract analysis by thin layer chromatography coupled to image. Food Sci. Technol. (Camp.) 36, 210–247 (2016)

    Article  Google Scholar 

  7. G. Brunner, Gas extraction: an introduction to fundamentals of supercritical fluids and the application to separation processes (Springer, Steinkopff, Darmstadt; New York, 1994)

    Book  Google Scholar 

  8. D.T. Santos, M.A.A. Meireles, Optimization of bioactive compounds extraction from jabuticaba (Myrciaria cauliflora) skins assisted by high pressure CO2. Innov. Food Sci. & Emerg. Technol. 12(3), 398–406 (2011). https://doi.org/10.1016/j.ifset.2011.02.004

    Article  CAS  Google Scholar 

  9. G.L. Zabot, M.N. Moraes, A.J. Petenate, M.A.A. Meireles, Influence of the bed geometry on the kinetics of the extraction of clove bud oil with supercritical CO2. J. Supercrit. Fluids 93, 56–66 (2014). https://doi.org/10.1016/j.supflu.2013.10.001

    Article  CAS  Google Scholar 

  10. Á.L. Santana, J.Q. Albarelli, D.T. Santos, R. Souza, N.T. Machado, M.E. Araújo, M.A.A. Meireles, Kinetic behavior, mathematical modeling, and economic evaluation of extracts obtained by supercritical fluid extraction from defatted assaí waste. Food Bioprod. Process. 107, 25–35 (2018). https://doi.org/10.1016/j.fbp.2017.10.006

    Article  Google Scholar 

  11. S. Pereda, S. Bottini, E. Brignole, Fundamentals of supercritical fluid technology, in Supercritical fluid extraction of nutraceuticals and bioactive compounds (CRC Press 2007), pp. 1–24. https://doi.org/10.1201/9781420006513.ch1

    Google Scholar 

  12. J.C.F. Johner, T. Hatami, G.L. Zabot, M.A.A. Meireles, Kinetic behavior and economic evaluation of supercritical fluid extraction of oil from pequi (Caryocar brasiliense) for various grinding times and solvent flow rates. J. Supercrit. Fluids 140, 188–195 (2018). https://doi.org/10.1016/j.supflu.2018.06.016

    Article  CAS  Google Scholar 

  13. D.T. Santos, C.L.C. Albuquerque, M.A.A. Meireles, Antioxidant dye and pigment extraction using a homemade pressurized solvent extraction system. Procedia Food Sci. 1, 1581–1588 (2011). https://doi.org/10.1016/j.profoo.2011.09.234

    Article  CAS  Google Scholar 

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Acknowledgements

The authors thank the Coordination for the Improvement of Higher Education Personnel (CAPES), National Counsel of Technological and Scientific Development (CNPq), the São Paulo Research Foundation (FAPESP) and for the financial support. M.A.A. Meireles thanks CNPq for the productivity grant (302423/2015-0).

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Correspondence to Diego T. Santos .

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Santos, D.T. et al. (2019). A Detailed Design and Construction of a Supercritical Antisolvent Precipitation Equipment. In: Supercritical Antisolvent Precipitation Process. SpringerBriefs in Applied Sciences and Technology. Springer, Cham. https://doi.org/10.1007/978-3-030-26998-2_1

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