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Routine Anticoagulation for the Provoked and Unprovoked VTE

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Abstract

The anticoagulation for venous thromboembolism (VTE) has changed significantly in the last few decades. Multiple agents with novel mechanisms of action have provided new ways of managing VTE, with lower bleeding risks and improved convenience for patients. Clinical studies have significantly enhanced our ability to determine the duration of anticoagulation and the management of thromboembolism in unusual locations. In addition special patient populations like VTE in the extremes of weight, thrombocytopenic patients, pregnancy, and renal failure can now be treated safer than ever before. This chapter will characterize the common therapies used to treat and manage patients with venous thromboembolism, in both provoked and unprovoked setting.

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Abbreviations

APS:

Antiphospholipid syndrome

BMI:

Body mass index

CVC:

Central venous catheter

CVST:

Cerebral venous sinus thrombosis

DOACs:

Direct oral anticoagulants

DVT:

Deep vein thrombosis

HIT:

Heparin-induced thrombocytopenia

HITT:

Heparin-induced thrombocytopenia and thrombosis

INR:

International normalized ratio

IVC:

Inferior vena cava

LMWH:

Low-molecular-weight heparin

NSAIDs:

Nonsteroidal anti-inflammatory drugs

OVT:

Ovarian vein thrombosis

PE:

Pulmonary embolism

PTS:

Post-thrombotic syndrome

UFH:

Unfractionated heparin

SVT:

Superficial venous thrombosis

VKA:

Vitamin K antagonist

VTE:

Venous thromboembolism

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Bosch, M. (2020). Routine Anticoagulation for the Provoked and Unprovoked VTE. In: Goubran, H., Ragab, G., Hassouna, S. (eds) Precision Anticoagulation Medicine. Springer, Cham. https://doi.org/10.1007/978-3-030-25782-8_2

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  • DOI: https://doi.org/10.1007/978-3-030-25782-8_2

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