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A 37-Year-Old Woman with Leg Weakness and CK Elevation

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A Case-Based Guide to Neuromuscular Pathology

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Abstract

We describe a case of a 37-year-old woman who presented with mild, slowly progressive, proximal limb muscle weakness. Examination showed mild proximal limb muscle weakness and bilateral calf hypertrophy. Serum creatine kinase level was moderately elevated. Electromyography study showed an irritable myopathy. Muscle biopsy revealed a lipid storage myopathy. Subsequent investigation revealed carnitine deficiency. The clinical presentation, muscle biopsy features, diagnostic evaluation, and management of lipid storage myopathies are briefly reviewed.

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Author information

Authors and Affiliations

  1. Department of Neurology and Neurotherapeutics, University of Texas Southwestern Medical Center, Dallas, TX, USA

    Elisabeth Golden

  2. Departments of Neurology and Pathology, Boston University Medical Center, Boston, MA, USA

    Lan Zhou

Authors
  1. Elisabeth Golden
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  2. Lan Zhou
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Correspondence to Elisabeth Golden .

Editor information

Editors and Affiliations

  1. Departments of Neurology and Pathology, Boston University Medical Center, Boston, MA, USA

    Lan Zhou

  2. Department of Pathology, Neuropathology Section, University of Texas Southwestern Medical Center, Dallas, TX, USA

    Dennis K. Burns

  3. Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX, USA

    Chunyu Cai

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Golden, E., Zhou, L. (2020). A 37-Year-Old Woman with Leg Weakness and CK Elevation. In: Zhou, L., Burns, D., Cai, C. (eds) A Case-Based Guide to Neuromuscular Pathology. Springer, Cham. https://doi.org/10.1007/978-3-030-25682-1_14

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  • DOI: https://doi.org/10.1007/978-3-030-25682-1_14

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-25681-4

  • Online ISBN: 978-3-030-25682-1

  • eBook Packages: MedicineMedicine (R0)

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