Abstract
Surgery represents the only potentially curative treatment for patients with colorectal liver metastasis, and patients with resectable and potentially resectable disease should undergo surgery or be converted resectable with chemotherapy.
The standard approach for synchronous metastasis comprises resection of the colorectal primary tumor, adjuvant chemotherapy, and then resection of the liver tumor. Other approaches are concomitant approach and reverse strategy. Most oncologists consider initial chemotherapy for a recently diagnosed resectable synchronous disease in order to assess the cancer biology prior to a surgical attempt. Progressive disease during systemic treatment indicates worse overall survival. If the hepatic metastases are resectable and the patient has an asymptomatic primary colon cancer, upfront surgical resection rather than initial chemotherapy may be offered for medically fit patients. In this chapter we discuss and summarise treatment algorithms for different presentations.
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Torres, O.J.M. et al. (2020). Algorithms for Patients with Colorectal Liver Metastasis. In: Correia, M., Choti, M., Rocha, F., Wakabayashi, G. (eds) Colorectal Cancer Liver Metastases. Springer, Cham. https://doi.org/10.1007/978-3-030-25486-5_12
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DOI: https://doi.org/10.1007/978-3-030-25486-5_12
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