Skip to main content
SpringerLink
Log in
Book cover

Atlas of Thyroid Cytopathology on Liquid-Based Preparations pp 185–198Cite as

Medullary Thyroid Carcinoma

  • Chapter
  • First Online:

  • 1023 Accesses

This is a preview of subscription content, log in via an institution.

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   89.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD   169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Suggested Reading

  1. Ali SZ, Cibas ES, editors. The Bethesda system for reporting thyroid cytopathology; definitions, criteria, and explanatory notes. 2nd ed. Cham: Springer International Publishing AG; 2018.

    Google Scholar 

  2. Canberk S, Onenerk M, Gunes P, Sayman E, Kilicoglu G. Oncocytic variant of medullary thyroid carcinoma. Endocr Pathol. 2015;26:320–3.

    Article  Google Scholar 

  3. Chang TC, Wu SL, Hsiao YL. Medullary thyroid carcinoma: pitfalls in diagnosis by fine needle aspiration cytology and relationship of cytomorphology to RET proto-oncogene mutations. Acta Cytol. 2005;49:477–82.

    Article  Google Scholar 

  4. Cibas ES, Ali SZ. The 2017 Bethesda system for reporting thyroid cytopathology. Thyroid. 2017;27:1341–6. https://doi.org/10.1089/thy.2017.0500.

    Article  Google Scholar 

  5. Dyhdalo KS, Chute DJ. Barriers to the recognition of medullary thyroid carcinoma on FNA: implications relevant to the new American Thyroid Association guidelines. Cancer Cytopathol. 2018;126:397–405. https://doi.org/10.1002/cncy.21990.

    Article  CAS  PubMed  Google Scholar 

  6. Elisei R, Bottici V, Luchetti F, Di Coscio G, Romei C, Grasso L, et al. Impact of routine measurement of serum calcitonin on the diagnosis and outcome of medullary thyroid cancer: experience in 10,864 patients with nodular thyroid disorders. J Clin Endocrinol Metab. 2004;89:163–8.

    Article  CAS  Google Scholar 

  7. Fadda G, Rossi ED. Liquid-based cytology in fine-needle aspiration biopsies of the thyroid gland. Acta Cytol. 2011;55:389–400. https://doi.org/10.1159/000329029.

    Article  CAS  PubMed  Google Scholar 

  8. Harach HR, Bergholm U. Medullary (C cell) carcinoma of the thyroid with features of follicular oxyphilic cell tumours. Histopathology. 1988;13:645–56.

    Article  CAS  Google Scholar 

  9. Haugen BR, Alexander EK, Bible KC, Doherty GM, Mandel SJ, Nikiforov YE, et al. 2015 American thyroid association management guidelines for adult patients with thyroid nodules and differentiated thyroid cancer: the American thyroid association guidelines task force on thyroid nodules and differentiated thyroid cancer. Thyroid. 2016;26(1):1–133.

    Article  Google Scholar 

  10. Hoda RS. Non-gynecologic cytology on liquid-based preparations: a morphologic review of facts and artifacts. Diagn Cytopathol. 2007;35:621–34.

    Article  Google Scholar 

  11. Hoda RS, VandenBussche C, Hoda SA. Diagnostic liquid-based cytology. New York: Springer; 2017.

    Book  Google Scholar 

  12. Kaushal S, Iyer VK, Mathur SR, Ray R. Fine needle aspiration cytology of medullary carcinoma of the thyroid with a focus on rare variants: a review of 78 cases. Cytopathology. 2011;22:95–105.

    Article  CAS  Google Scholar 

  13. Papaparaskeva K, Nagel H, Droese M. Cytologic diagnosis of medullary carcinoma of the thyroid gland. Diagn Cytopathol. 2000;22:351–8.

    Article  CAS  Google Scholar 

  14. Sams SB, Tompkins KD, Mayson S, Raeburn CD, Mehrotra S. Oncocytic variant of medullary thyroid carcinoma; a rare tumor with numerous diagnostic mimics by fine needle aspiration. Diagn Cytopathol. 2017;45:1148–52. https://doi.org/10.1002/dc.23790.

    Article  PubMed  Google Scholar 

  15. Seningen JL, Nassar A, Henry MR. Correlation of thyroid nodule fine-needle aspiration cytology with corresponding histology at Mayo Clinic, 2001-2007: an institutional experience of 1,945 cases. Diagn Cytopathol. 2012;40:E27–32. https://doi.org/10.1002/dc.21566.

    Article  PubMed  Google Scholar 

  16. Suzuki A, Hirokawa M, Takada N, Higuchi M, Ito A, Yamao N, et al. Fine-needle aspiration cytology for medullary thyroid carcinoma: a single institutional experience in Japan. Endocr J. 2017;64:1099–104. https://doi.org/10.1507/endocrj.EJ17-0238.

    Article  CAS  PubMed  Google Scholar 

  17. Tranchida P, Estigarribia J, Sethi S, Giorgadze T. Cytologic diagnosis of recurrent medullary thyroid carcinoma with oncocytic change twenty-one years post thyroidectomy: case report & review of the literature. Diagn Cytopathol. 2011;39:641–6.

    Article  Google Scholar 

  18. Trimboli P, Cremonini N, Ceriani L, Saggiorato E, Guidobaldi L, Romanelli F, et al. Calcitonin measurement in aspiration needle washout fluids has higher sensitivity than cytology in detecting medullary thyroid cancer: a retrospective multicentre study. Clin Endocrinol. 2014;80:135–40.

    Article  CAS  Google Scholar 

  19. Trimboli P, Treglia G, Guidobaldi L, Romanelli F, Nigri G, Valabrega S, et al. Detection rate of FNA cytology in medullary thyroid carcinoma: a meta-analysis. Clin Endocrinol. 2015;82:280–5.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Pathology and Laboratory Medicine, New York Presbyterian Hospital, Weill Cornell Medical College, New York, NY, USA

    Rema Rao & Theresa Scognamiglio

  2. CBLPath, Rye Brook, NY, USA

    Rana S. Hoda

Authors
  1. Rema Rao
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Theresa Scognamiglio
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Rana S. Hoda
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Rana S. Hoda .

Editor information

Editors and Affiliations

  1. CBLPath, Rye Brook, NY, USA

    Rana S. Hoda

  2. Weill Cornell Medical College, NewYork–Presbyterian Hospital, New York, NY, USA

    Rema Rao

  3. Weill Cornell Medical College, NewYork–Presbyterian Hospital, New York, NY, USA

    Theresa Scognamiglio

Rights and permissions

Reprints and permissions

Copyright information

© 2020 Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Rao, R., Scognamiglio, T., Hoda, R.S. (2020). Medullary Thyroid Carcinoma. In: Hoda, R., Rao, R., Scognamiglio, T. (eds) Atlas of Thyroid Cytopathology on Liquid-Based Preparations. Springer, Cham. https://doi.org/10.1007/978-3-030-25066-9_10

Download citation

  • DOI: https://doi.org/10.1007/978-3-030-25066-9_10

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-25065-2

  • Online ISBN: 978-3-030-25066-9

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation