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Lungs, Mediastinum, and Pleura

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Atlas of Cytopathology and Radiology

Abstract

Transthoracic and transbronchial fine needle aspiration (FNA) and core biopsies are the main methods used to diagnose mass lesions in the lung parenchyma, pleura, and mediastinum, and these techniques can also be used to confirm benign neoplasms, infections, and inflammatory lesions. Transthoracic FNA/biopsy is the best method for diagnosing small peripheral lesions, while endoscopic ultrasound-guided FNA (EUS FNA) is the preferred method for biopsy of central lesions. FNA biopsy is particularly useful to distinguish between small cell carcinoma and non–small cell carcinoma and is critical to help stage non–small cell lung carcinoma patients. In most cases, the diagnostic benefit of the FNA procedure far outweighs the risk of complications. Therefore, FNA biopsy can significantly impact patient management while avoiding more invasive procedures and unnecessary surgeries.

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Authors and Affiliations

  1. Northwestern University, Feinberg School of Medicine, Northwestern Memorial Hospital, Chicago, IL, USA

    Xiaoqi Lin

  2. Department of Pathology, Edward Hospital, Naperville, IL, USA

    Julianne M. Ubago

  3. Department of Radiology, Section of Vascular and Interventional Radiology, Northwestern University, Chicago, IL, USA

    Rehan Ali & Ali Al Asadi

  4. Department of Pathology, Northwestern Medicine, Chicago, IL, USA

    Ahsun Riaz

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  1. Xiaoqi Lin
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  2. Julianne M. Ubago
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  3. Rehan Ali
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  4. Ali Al Asadi
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  5. Ahsun Riaz
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Correspondence to Xiaoqi Lin .

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Editors and Affiliations

  1. Northwestern University Feinberg School of Medicine, Northwestern Memorial Hospital, Chicago, IL, USA

    Ritu Nayar

  2. Northwestern University Feinberg School of Medicine, Northwestern Memorial Hospital, Chicago, IL, USA

    Xiaoqi Lin

  3. Northshore Medical Group, Evanston Hospital, Evanston, IL, USA

    Ajit S. Paintal

  4. Northwestern University Feinberg School of Medicine, Chicago, IL, USA

    Ramona Gupta

  5. Northwestern University Feinberg School of Medicine, Chicago, IL, USA

    Albert A. Nemcek Jr.

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Lin, X., Ubago, J.M., Ali, R., Al Asadi, A., Riaz, A. (2020). Lungs, Mediastinum, and Pleura. In: Nayar, R., Lin, X., Paintal, A., Gupta, R., Nemcek Jr., A. (eds) Atlas of Cytopathology and Radiology. Springer, Cham. https://doi.org/10.1007/978-3-030-24756-0_3

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  • DOI: https://doi.org/10.1007/978-3-030-24756-0_3

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