Abstract
Pulse decomposition analysis (PDA) uses a pulse contour analysis approach to quantify hemodynamic parameters such as blood pressure and arterial tone changes. It is based on the concept that two central reflection sites are responsible for the shape of the pressure pulse envelope of the upper body.
The two reflection sites, one located at the aortic juncture of thoracic and abdominal aortas, and the other at the iliac bifurcation, reflect the primary left ventricular ejection pulse to give rise to two reflected and two re-reflected component pulses. Within the pulse pressure envelope of each cardiac cycle these five component pulses arrive sequentially in the arterial periphery. Quantification of the temporal and amplitudinal behavior of the first three component pulses establishes a formalism that can be used to monitor certain hemodynamic states and their changes.
The observational evidence and motivation for PDA are presented, as are pulse modeling approaches, practical implementation considerations and physiological confounders. Benchmark and clinical study comparisons are provided. The current status and outlook of the CareTaker physiological monitor, which utilizes PDA as its operational principle and has demonstrated compliance with several regulatory standards, are described.
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Baruch, M.C. (2019). Pulse Decomposition Analysis Techniques. In: Solà, J., Delgado-Gonzalo, R. (eds) The Handbook of Cuffless Blood Pressure Monitoring. Springer, Cham. https://doi.org/10.1007/978-3-030-24701-0_7
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