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Translational Research and Onco-Omics Applications in the Era of Cancer Personal Genomics pp 1–7Cite as

Pharmaco-Geno-Proteo-Metabolomics and Translational Research in Cancer

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Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 1168))

Abstract

The diagnosis, prognosis and treatment of cancer has had a great improvement due to the “omics” technologies such as genomics, proteomics, epigenomics, pharmacogenomics, and metabolomics. The technological progress of these technologies has allowed precision medicine to become a clinical reality. The study of different biomolecules such as DNA, RNA and proteins has helped to detect alterations in genes, changes in gene expression profiles and loss or gain of protein function, which allows us to make associations and better understand the cancer biology. Data obtained from different “omics” technologies gives a complementary spectrum of information that helps us to understand and unveil new information for a better diagnosis, prognosis, prediction of new molecular targets of anticancer therapies, etc. This chapter presents a general landscape of the interaction between the Pharmaco-Geno-Proteo-Metabolomic and translational medicine research in cancer.

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Author information

Authors and Affiliations

  1. Computational Genomics Laboratory, Instituto Nacional de Medicina Genomica, Mexico City, Mexico

    Edith A. Fernández-Figueroa, Jorge E. Peña-Velasco & Claudia Rangel-Escareño

  2. Translational Medicine Laboratory, Instituto Nacional de Cancerologia, Mexico City, Mexico

    Edith A. Fernández-Figueroa & Jorge E. Peña-Velasco

  3. Pathology Department, Instituto Nacional de Cancerologia, Mexico City, Mexico

    Saul Lino-Silva

Authors
  1. Edith A. Fernández-Figueroa
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  2. Saul Lino-Silva
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  3. Jorge E. Peña-Velasco
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  4. Claudia Rangel-Escareño
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Corresponding author

Correspondence to Edith A. Fernández-Figueroa .

Editor information

Editors and Affiliations

  1. Department of Gastrointestinal Medical Oncology & Translational Medicine Laboratory, Instituto Nacional de Cancerologia, Mexico City, Mexico

    Erika Ruiz-Garcia

  2. Translational Research Laboratory in Cancer & Celullar Therapy, Hospital de Oncologia, Siglo XXI, IMSS, Mexico City, Mexico

    Horacio Astudillo-de la Vega

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Fernández-Figueroa, E.A., Lino-Silva, S., Peña-Velasco, J.E., Rangel-Escareño, C. (2019). Pharmaco-Geno-Proteo-Metabolomics and Translational Research in Cancer. In: Ruiz-Garcia, E., Astudillo-de la Vega, H. (eds) Translational Research and Onco-Omics Applications in the Era of Cancer Personal Genomics. Advances in Experimental Medicine and Biology, vol 1168. Springer, Cham. https://doi.org/10.1007/978-3-030-24100-1_1

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