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Cervical Cytology with Squamous and Glandular Abnormalities

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Book cover Practical Cytopathology

Part of the book series: Practical Anatomic Pathology ((PAP))

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Abstract

The most common epithelial cell abnormalities in cervical cytology are abnormal squamous cells and glandular cells. According to the third edition of the Bethesda System for Reporting Cervical Cytology (2015), there are four categories in squamous cell abnormalities: atypical squamous cells (ASC), low-grade squamous intraepithelial lesion (LSIL), high-grade squamous intraepithelial lesion (HSIL), and squamous cell carcinoma. ASC is further classified into atypical squamous cells – of undetermined significance (ASC-US) and atypical squamous cells – cannot exclude HSIL (ASC-H). LSIL encompasses human papillomavirus (HPV) infection/mild dysplasia/cervical intraepithelial neoplasia (CIN 1). HSIL encompasses moderate dysplasia (CIN 2), severe dysplasia (CIN 3), and carcinoma in situ (CIS). According to this book, there are also four categories in glandular cell abnormalities: atypical glandular cells, not otherwise specified (NOS) (including atypical endocervical cells, NOS; atypical endometrial cells, NOS; and atypical glandular cells, NOS); atypical glandular cells, favor neoplastic (including atypical endocervical cells, favor neoplastic and atypical glandular cells, favor neoplastic); endocervical adenocarcinoma in situ; and adenocarcinoma (including endocervical, endometrial, extrauterine and NOS).

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Authors and Affiliations

  1. Department of Pathology and Laboratory Medicine, Cooper Medical School of Rowan University, Camden, NJ, USA

    Shuyue Ren

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  1. Shuyue Ren
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Correspondence to Shuyue Ren .

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Editors and Affiliations

  1. VA Boston Healthcare System, Boston, MA, USA

    Huihong Xu

  2. Brigham and Women’s Hospital, Boston, MA, USA

    Xiaohua Qian

  3. Robert Wood Johnson University Hospital, New Brunswick, NJ, USA

    He Wang

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Ren, S. (2020). Cervical Cytology with Squamous and Glandular Abnormalities. In: Xu, H., Qian, X., Wang, H. (eds) Practical Cytopathology . Practical Anatomic Pathology. Springer, Cham. https://doi.org/10.1007/978-3-030-24059-2_5

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  • DOI: https://doi.org/10.1007/978-3-030-24059-2_5

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  • Publisher Name: Springer, Cham

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  • Online ISBN: 978-3-030-24059-2

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