Abstract
Because Breast Histopathology Image Analysis (BHIA) plays a very important role in breast cancer diagnosis and medical treatment processes, more and more effective Machine Learning (ML) techniques are developed and applied in this field to assist histopathologists to obtain a more rapid, stable, objective, and quantified analysis result. Among all the applied ML algorithms in the BHIA field, Artificial Neural Networks (ANNs) show a very positive and healthy development trend in recent years. Hence, in order to clarify the development history and find the future potential of ANNs in the BHIA field, we survey more than 60 related works in this paper, referring to classical ANNs, deep ANNs and methodology analysis.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsReferences
Acs, B., Rimm, D.: Not just digital pathology, intelligent digital pathology. J. Am. Med. Assoc. 4(3), 403–404 (2018)
Anuranjeeta, Shukla, K., Tiwari, A., Sharma, S.: Classification of histopathological images of breast cancerous and non cancerous cells based on morphological features. Biomed. Pharmacol. J. 10(1), 353–366 (2017)
Araujo, T., Aresta, G., Castro, E., et al.: Classification of breast cancer histology images using convolutional neural networks. Plos One 12(6), 1–14 (2017)
Arevalo, J., Cruz-Roa, A., Gonzelez, F.: Histopathology image representation for automatic analysis: a state-of-the-art review. Revista Med 22(2), 79–91 (2014)
Aswathy, M., Jagannath, M.: Detection of breast cancer on digital histopathology images: present status and future possibilities. Inform. Med. Unlocked 8, 74–79 (2017)
Bayramoglu, N., Kannala, J., Heikkilae, J.: Deep learning for magnification independent breast cancer histopathology image classification. In: Proceedings of ICPR 2016 (2016)
Bejnordi, B., Veta, M., Diest., P., et al.: Diagnostic assessment of deep learning algorithms for detection of lymph node metastases in women with breast cancer. JAMA 318(22), 2199–2210 (2017)
BenTaieb, A., Hamarneh, G.: Predicting cancer with a recurrent visual attention model for histopathology images. In: Proceedings of MICCAI 2018, pp. 129–137 (2018)
Bhattacharjee, S., et al.: Review on histopathological slide analysis using digital microscopy. Int. J. Adv. Sci. Technol. 62, 65–96 (2014)
Chen, J., Li, Y., Xu, J., et al.: Computer-aided prognosis on breast cancer with hematoxylin and eosin histopathology images: a review. Tumor Biol. 39(3), 1–12 (2017)
Chervony, L., Polak, S.: Fast Classification of Whole Slide Histopathology Images for Breast Cancer Detection. Camelyon Grand Challenge 2017 (2017)
Ciresan, D., et al.: Mitosis detection in breast cancer histology images with deep neural networks. In: Proceedings of MICCAI 2013, pp. 411–418 (2013)
Demir, C., Yener, B.: Automated cancer diagnosis based on histopathological images: a systematic survey. Technical Report, Rensselaer Polytechnic Institute, Department of Computer, TR-05-09 (2005)
Du, B., Qi, Q., Zheng, H., et al.: Breast cancer histopathological image classification via deep active learning and confidence boosting. In: Proceedings of ICANN 2018, pp. 109–116 (2018)
Gandomkar, Z., Brennan, P., Mello-Thoms, C.: A framework for distinguishing benign from malignant breast histopathological images using deep residual networks. In: Proceedings of SPIE 10718 (2018)
Gecer, B., Aksoy, S., Mercan, E., et al.: Detection and classification of cancer in whole slide breast histopathology images using deep convolutional networks. Pattern Recognit. 84, 345–356 (2018)
Gil, J., Wu, H., Wang, B.Y.: Image analysis and morphometry in the diagnosis of breast cancer. Microsc. Res. Tech. 59(2), 109–118 (2002)
Golatkar, A., Anand, D., Sethi, A.: Classification of breast cancer histology using deep learning. arXiv Breast Cancer Histology Challenge 2018 (2018)
Guo, G., Dyer, C.: Learning from examples in the small sample case: face expression recognition. IEEE Trans. Syst. Man Cybern. 35(3), 477–488 (2005)
Gurcan, M., Boucheron, L., Can, A., et al.: Histopathological image analysis: a review. IEEE Rev. Biomed. Eng. 2, 147–171 (2009)
Han, Z., Wei, B., Zheng, Y., et al.: Breast cancer multi-classification from histopathological images with structured deep learning model. Sci. Rep. 7(4172), 1–10 (2017)
He, L., Long, L., Antani, S., Thoma, G.: Computer assisted diagnosis in histopathology. In: Zhao, Z. (ed.) Sequence and Genome Analysis: Methods and Applications, pp. 271–287. iConcept Press, Hong Kong (2010)
He, L., Long, L., Antani, S., Thoma, G.: Histology image analysis for carcinoma detection and grading. Comput. Methods Programs Biomed. 107(3), 538–556 (2012)
Irshad, H., Veillard, A., Roux, L., Racoceanu, D.: Methods for nuclei detection, segmentation, and classification in digital histopathology: a review - current status and future potential. IEEE Rev. Biomed. Eng. 7, 97–114 (2014)
Kiambe, K.: Breast histopathological image feature extraction with convolutional neural networks for classification. ICSES Trans. Image Process. Pattern Recognit. 4(2), 4–12 (2018)
Kowal, M., et al.: Computer-aided diagnosis of breast cancer based on fine needle biopsy microscopic images. Comput. Biol. Med. 43(10), 1563–1572 (2013)
Lee, G., et al.: Deep learning and color variability in breast cancer histopathological images: a preliminary study. In: Proceedings of SPIE 10718 (2018)
Li, Q., Li, W.: Using Deep Learning for Breast Cancer Diagnosis. Technical Report, Chinese University of Hong Kong, China (2017)
Litjens, G., et al.: Deep learning as a tool for increased accuracy and efficiency of histopathology diagnosis. Sci. Rep. 6(26286), 1–11 (2016)
Liu, Y., Gadepalli, K., Norouzi, M., et al.: Detecting Cancer Metastases on Gigapixel Pathology Images. arXiv Camelyon Grand Challenge 2016 (2017)
Loukas, C., Kostopoulos, S., Tanoglidi, A., et al.: Breast cancer characterization based on image classification of tissue sections visualized under low magnification. Comput. Math. Methods Med. 2013, 1–8 (2013)
Mahbod, A., et al.: Breast cancer histological image classification using fine-tuned deep network fusion. In: Proceedings of ICIAR 2018, pp. 754–762 (2018)
Malon, C., Cosatto, E.: Classification of mitotic figures with convolutional neural networks and seeded blob features. J. Pathol. Inform. 4(8) (2013)
Malona, C., et al.: Mitotic figure recognition: agreement among pathologists and computerized detector. Anal. Cell. Pathol. 35(2), 97–100 (2012)
Motlagh, M., Jannesari, M., Aboulkheyr, H., et al.: Breast Cancer Histopathological Image Classification: A Deep Learning Approach. bioRxiv (2018)
Mouelhi, A., Sayadi, M., Fnaiech, F.: A supervised segmentation scheme based on multilayer neural network and color active contour model for breast cancer nuclei detection. In: Proceedings of ICEESA, pp. 1–6 (2013)
Nahid, A., Kong, Y.: Histopathological breast-image classification using local and frequency domains by convolutional neural network. Information 9(19), 1–26 (2018)
Nahid, A., Mehrabi, M., Kong, Y.: Histopathological breast Cancer image classification by deep neural network techniques guided by local clustering. BioMed Res. Int. 2018, 1–20 (2018)
Nahid, A., Mikaelian, A., Kong, Y.: Histopathological breast-image classification with restricted boltzmann machine along with backpropagation. Biomed. Res. 29(10), 2068–2077 (2018)
Nawaz, M., Sewissy, A., Soliman, T.: Automated classification of breast cancer histology images using deep learning based convolutional neural networks. Int. J. Comput. Sci. Netw. Secur. 18(4), 152–160 (2018)
Nawaz, M., Sewissy, A., Soliman, T.: Multi-class breast cancer classification using deep learning convolutional neural network. Int. J. Adv. Comput. Sci. Appl. 9(6), 316–332 (2018)
Nazeri, K., et al.: Two-stage convolutional neural network for breast cancer histology image classification. arXiv Breast Cancer Histology Challenge 2018
Nejad, E., Affendey, L., Latip, R., Ishak, I.: Classification of histopathology images of breast into benign and malignant using a single-layer convolutional neural network. In: Proceedings of ICISPC 2017, pp. 50–53 (2017)
Nielsen, M.: Neural Networks and Deep Learning. Determination Press (2015)
Pang, B., Zhang, Y., Chen, Q., et al.: Cell nucleus segmentation in color histopathological imagery using convolutional networks. In: Proceedings of CCPR, pp. 1–5 (2010)
Petushi, S., Garcia, P., Haber, M., et al.: Large-scale computations on histology images reveal grade-differentiating parameters for breast cancer. BMC Med. Imaging 6(14), 1–11 (2006)
Rakhlin, A., Shvets, A., Iglovikov, V., Kalinin, A.: Deep convolutional neural networks for breast cancer histology image analysis. In: Proceedings of ICIAR 2018, pp. 737–744 (2018)
Ramos-Vara, J.: Principles and methods of immunohistochemistry. In: Gautier, J. (ed.) Drug Safety Evaluation. Methods in Molecular Biology (Methods and Protocols), vol. 691, pp. 83–96. Springer, Humana Press, Germany (2011)
Ranjan, N., et al.: Hierarchical approach for breast cancer histopathology images classification. In: Proceedings of MIDL 2018, pp. 1–7 (2018)
Shallu, Mehra, R.: Breast cancer histology images classification: training from scratch or transfer learning? ICT Express 4(4), 247–254 (2018)
Siegel, R., Miller, K., Fedewa, S., et al.: Colorectal cancer statistics, 2017. CA Cancer J. Clin. 67(3), 177–193 (2017)
Singh, S., Gupta, P., Sharma, M.: Breast cancer detection and classification of histopathological images. Int. J. Eng. Sci. Tech. (IJEST) 3(5), 4228–4332 (2011)
Song, Y., Zou, J., Chang, H., Cai, W.: Adapting fisher vectors for histopathology image classification. In: Proceedings of ISBI 2017, pp. 600–603 (2017)
Spanhol, F.: Automatic breast cancer classification from histopathological images: a hybrid approach. Ph.D. thesis. Federal University of Parana, Brazil (2018)
Spanhol, F., et al.: Deep features for breast cancer histopathological image classification. In: Proceedings of SMC, pp. 1868–1873 (2017)
Spanhol, F., et al.: A dataset for breast cancer histopathological image classification. IEEE Trans. Biomed. Eng. 63(7), 1455–1462 (2016)
Spanhol, F., et al.: Breast cancer histopathological image classification using convolutional neural networks. In: Proceedings of IJCNN (2016)
Steiner, D., MacDonald, R., Liu, Y., et al.: Impact of deep learning assistance on the histopathologic review of lymph nodes for metastatic breast cancer. Am. J. Surg. Pathol. 42(12), 1636–1646 (2018)
Theodoridis, S., Koutroumbas, K.: Pattern Recognition, 4th edn. Elsevier (2009)
Vapnik, V.: Statistical Learning Theory. Wiley-Interscience, US (1998)
Veta, M.: Breast cancer histopathology image analysis. Ph.D. thesis in Utrecht University, Netherlands (2014)
Veta, M., Pluim, J., Diest, P., Viergever, M.: Breast cancer histopathology image analysis: a review. IEEE Trans. Biomed. Eng. 61(5), 1400–1411 (2014)
Wang, D., Khosla, A., Gargeya, R., et al.: Deep learning for identifying metastatic breast cancer. arXiv Camelyon Grand Challenge 2016 (2016)
Wang, H., Cruz-Roa, A., Basavahally, A., et al.: Cascaded ensemble of convolutional neural networks and handcrafted features for mitosis detection. In: Proceedings of SPIE 9041 (2014)
Wang, Z., Dong, N., Dai, W., et al.: Classification of breast cancer histopathological images using convolutional neural networks with hierarchical loss and global pooling. In: Proceedings of ICIAR 2018, pp. 745–753 (2018)
Wu, J., Shi, J., Li, Y., et al.: Histopathological image classification using random binary hashing based PCANet and bilinear classifier. In: Proceedings of EUSIPCO, pp. 2050–2054 (2016)
Xu, J., Xiang, L., Liu, Q., et al.: Stacked sparse autoencoder (SSAE) for nuclei detection on breast cancer histopathology images. IEEE Trans. Med. Imaging 35(1), 119–130 (2016)
Zhang, Y., Zhang, B., Coenen, F., Lu, W.: Breast cancer diagnosis from biopsy images with highly reliable random subspace classifier ensembles. Mach. Vis. Appl. 24(7), 1405–1420 (2013)
Zhang, Y., Zhang, B., Lu, W.: Breast cancer classification from histological images with multiple features and random subspace classifier ensemble. In: Proceedings of AIP 1371, no. 1, pp. 19–28 (2011)
Zhang, Y., Zhang, B., Lu, W.: Breast cancer histological image classification with multiple features and random subspace classifier ensemble. In: Pham, T.D., Jain, L.C. (eds.) Knowledge-based Systems in Biomedicine, SCI 450, pp. 27–42. Springer, Germany (2013)
Zhi, W., Yueng, H., Chen, Z., et al.: Using transfer learning with convolutional neural networks to diagnose breast cancer from histopathological images. In: Proceeding of ICONIP 2017, pp. 669–676 (2017)
Acknowledgment
We thank the funds supported by the “National Natural Science Foundation of China” (No. 61806047), the “Fundamental Research Funds for the Central Universities” (No. N171903004), and the “Scientific Research Launched Fund of Liaoning Shihua University” (No. 2017XJJ-061). We also thank Dan Xue, due to her contribution is considered as the same important as the first author in this paper.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2019 Springer Nature Switzerland AG
About this paper
Cite this paper
Li, C. et al. (2019). A Survey for Breast Histopathology Image Analysis Using Classical and Deep Neural Networks. In: Pietka, E., Badura, P., Kawa, J., Wieclawek, W. (eds) Information Technology in Biomedicine. ITIB 2019. Advances in Intelligent Systems and Computing, vol 1011. Springer, Cham. https://doi.org/10.1007/978-3-030-23762-2_20
Download citation
DOI: https://doi.org/10.1007/978-3-030-23762-2_20
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-030-23761-5
Online ISBN: 978-3-030-23762-2
eBook Packages: Intelligent Technologies and RoboticsIntelligent Technologies and Robotics (R0)