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Urological Care for Patients with Diabetes-Induced Lower Urinary Tract Dysfunction

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Urological Care for Patients with Progressive Neurological Conditions

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Abstract

Diabetic cystopathy is a common and costly complication of the disease. The main driver for bladder dysfunction in this disease process is hyperglycemia. This leads to tissue damage in particularly susceptible cells. In diabetic cystopathy, hyperglycemia contributes to progressive loss of nerve fibers, which affects both the autonomic and somatic divisions of the nervous system. Urologic sequelae of diabetes include lower urinary tract dysfunction as well as sexual dysfunction. The process is slowly progressive and insidious. A common finding is impaired bladder sensation, which can lead to an asymptomatic increase in bladder capacity and urinary retention. The detrusor remodeling that occurs can also cause overactive bladder symptoms. Symptom presentation is widely variable and may go unnoticed for many years. Urodynamics can be the cornerstone of diagnosis in many cases. Treatments vary depending on subtype of bladder dysfunction and generally have lower success rates due to the irreversible loss of detrusor sensory and contractile ability.

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Authors and Affiliations

  1. University of California – San Diego Health, La Jolla, CA, USA

    Kelly Bree & Yahir Santiago-Lastra

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  1. Kelly Bree
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  2. Yahir Santiago-Lastra
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Correspondence to Yahir Santiago-Lastra .

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Editors and Affiliations

  1. Division of Neurourology and Pelvic Reconstruction, Department of Urology, University of Michigan Medical School, Ann Arbor, MI, USA

    John T. Stoffel

  2. Division of Urology, Department of Surgery, Greenville Health System, Greenville, SC, USA

    Elizabeth V. Dray

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Bree, K., Santiago-Lastra, Y. (2020). Urological Care for Patients with Diabetes-Induced Lower Urinary Tract Dysfunction. In: Stoffel, J.T., Dray, E.V. (eds) Urological Care for Patients with Progressive Neurological Conditions. Springer, Cham. https://doi.org/10.1007/978-3-030-23277-1_18

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  • DOI: https://doi.org/10.1007/978-3-030-23277-1_18

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-23276-4

  • Online ISBN: 978-3-030-23277-1

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