Abstract
The Golgi apparatus plays a central role in the numerous traffic tasks in cells. Whereas the well-investigated chemical signaling is sufficient to explain the information processes in the secretory output of cells, it is insufficient to do that for the substitution of structural elements in the three-dimensional space of the cell. Here we review recent work (Jaross, Front Biosci 23:940–946, 2018) suggesting that molecular vibration patterns of those macromolecules which have to be exchanged are recognized by molecules in the Golgi via resonance of the electromagnetic fingerprints. That results in the activation of specific molecules and induction of the whole substitution process. For bridging intracellular distances, the IR radiation must be coherent. It is discussed that coherence is achieved by chemical reaction during the changing process of the molecule along with the quasicrystalline structure of the neighboring water molecules. Several aspects of the relevance of that signaling to the direct interactions of molecules during various intracellular processes are discussed.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Alberts B (2017) Molecular biology of the cell. Garland Science, New York. https://doi.org/10.1201/9781315735368
Balabanian L, Berger CL, Hendricks AG (2016) The role of the microtubule cytoskeleton in regulating intracellular transport. Biophys J 110(3):466a. https://doi.org/10.1016/j.bpj.2015.11.2494
Barghouth PG, Thiruvalluvan M, Oviedo NJ (2015) Bioelectrical regulation of cell cycle and the planarian model system. Biochim Biophys Acta 1848(10 Pt B):2629–2637. https://doi.org/10.1016/j.bbamem.2015.02.024
Barzanjeh S, Salari V, Tuszynski JA, Cifra M, Simon C (2017) Monitoring microtubule mechanical vibrations via optomechanical coupling. bioRxiv. https://doi.org/10.1101/097725
Brown RW, Cheng YC, Haacke EM, Thompson MR, Venkatesan R (2014) Electromagnetic principles. In: Magnetic resonance imaging. Wiley, London. https://doi.org/10.1002/9781118633953.app1
Chee HK, Oh SJ (2013) Molecular vibration-activity relationship in the agonism of adenosine receptors. Genomics Inform 11(4):282–288. https://doi.org/10.5808/GI.2013.11.4.282
Chee HK, Yang JS, Joung JG, Zhang BT, Oh SJ (2015) Characteristic molecular vibrations of adenosine receptor ligands. FEBS Lett 589(4):548–552. https://doi.org/10.1016/j.febslet.2015.01.024
Chernet BT, Levin M (2013) Transmembrane voltage potential is an essential cellular parameter for the detection and control of tumor development in a Xenopus model. Dis Model Mech 6(3):595–607. https://doi.org/10.1242/dmm.010835
Cifra M, Pospisil P (2014) Ultra-weak photon emission from biological samples: definition, mechanisms, properties, detection and applications. J Photochem Photobiol B 139:2–10. https://doi.org/10.1016/j.jphotobiol.2014.02.009
Córdova MO, Flores Ramírez CI, Bejarano BV, Arroyo Razo GA, Pérez Flores FJ, Tellez VC, Ruvalcaba RM (2011) Comparative study using different infrared zones of the solventless activation of organic reactions. Int J Mol Sci 12(12):8575–8580
Cosic I (1994) Macromolecular bioactivity: is it resonant interaction between macromolecules? – Theory and applications. IEEE Trans Biomed Eng 41(12):1101–1114. https://doi.org/10.1109/10.33585
Cosic I, Pirogova E, Vojisavljevic V, Fang Q (2006) Electromagnetic properties of biomolecules. FME Trans 34:71–801
Cosic I, Cosic D, Lazar K (2015) Is it possible to predict electromagnetic resonances in proteins, DNA and RNA? EPJ Nonlinear Biomed Phys 3(1):5. https://doi.org/10.1140/epjnbp/s40366-015-0020-6
Cosic I, Cosic D, Lazar K (2016) Environmental light and its relationship with electromagnetic resonances of biomolecular interactions, as predicted by the resonant recognition model. Int J Environ Res Public Health 13(7):647. https://doi.org/10.3390/ijerph130706
De Ninno AD (2017) Dynamics of formation of the exclusion zone near hydrophilic surfaces. Chem Phys Lett 667:322–326. https://doi.org/10.1016/j.cplett.2016.11.015
De Ninno AD, Pregnolato M (2017) Electromagnetic homeostasis and the role of low-amplitude electromagnetic fields on life organization. Electromagn Biol Med 36(2):115–122. https://doi.org/10.1080/15368378.2016.1194293
De Ninno AD, Castellano AC, Giudice ED (2013) The supramolecular structure of liquid water and quantum coherent processes in biology. J Phys Conf Ser 442:012031. https://doi.org/10.1088/1742-6596/442/1/012031
Dotta BT (2016) Ultra-weak photon emissions differentiate malignant cells from non-malignant cells in vitro. Arch Cancer Res 4(2):85. https://doi.org/10.21767/2254-6081.100085
Foletti A, Grimaldi S, Lisi A, Ledda M, Liboff AR (2013) Bioelectromagnetic medicine: the role of resonance signaling. Electromagn Biol Med 32(4):484–499. https://doi.org/10.3109/15368378.2012.743908
Foletti A, Ledda M, Grimaldi S, D’Emilia E, Giuliani L, Liboff A, Lisi A (2015) The trail from quantum electro dynamics to informative medicine. Electromagn Biol Med 34(2):147–150. https://doi.org/10.3109/15368378.2015.1036073
Funk RH (2015) Endogenous electric fields as guiding cue for cell migration. Front Physiol 6:143. https://doi.org/10.3389/fphys.2015.00143
Funk RH (2018) Biophysical mechanisms complementing ldquo classical rdquo cell biology. Front Biosci 23(3):921–939. https://doi.org/10.2741/4625
Gu Q (1992) Quantum theory of biophoton emission. Recent advances in biophoton research and its applications, pp 59–112. https://doi.org/10.1142/9789814439671_0003
Gyoeva FK (2014) The role of motor proteins in signal propagation. Biochemistry (Mosc) 79(9):849–855. https://doi.org/10.1134/S0006297914090028
Haltiwanger SG (2010) The science of bioenergetic and bioelectric. Technologies formatted full-text article
Havelka D, Cifra M, Kucera O (2014) Multi-mode electro-mechanical vibrations of a microtubule: in silico demonstration of electric pulse moving along a microtubule. Appl Phys Lett 104(24):243702. https://doi.org/10.1063/1.48841180
Hoeprich G, Hancock W, Berger C (2015) Kinesin-2’s role in intracellular cargo transport: navigating the complex microtubule landscape. Biophys J 108(2):135a–136a. https://doi.org/10.1016/j.bpj.2014.11.750
Jaross W (2015) Hypothesis on a signaling system based on molecular vibrations of structure forming macromolecules in cells and tissues. Integr Mol Med 2(5). https://doi.org/10.15761/IMM.1000168
Jaross W (2016) Are molecular vibration patterns of cell structural elements used for intracellular signalling? Open Biochem J 10:12–16. https://doi.org/10.2174/1874091X01610010012
Jaross W (2018) Hypothesis on interactions of macromolecules based on molecular vibration patterns in cells and tissues. Front Biosci 23(3):940–946. https://doi.org/10.2741/4626
Kobayashi M, Takeda M, Sato T, Yamazaki Y, Kaneko K, Ito K, Kato H, Inaba H (1999) In vivo imaging of spontaneous ultraweak photon emission from a rat’s brain correlated with cerebral energy metabolism and oxidative stress. Neurosci Res 34(2):103–113. https://doi.org/10.1016/S0168-0102(99)00040-1
Kucera O, Cifra M (2013) Cell-to-cell signaling through light: just a ghost of chance? Cell Commun Signal 11:87. https://doi.org/10.1186/1478-811X-11-87
Lemeshko M, Krems RV, Doyle JM, Kais S (2013) Manipulation of molecules with electromagnetic fields. Mol Phys 111(12–13):1648–1682. https://doi.org/10.1080/00268976.2013.813595
Levin M (2012) Molecular bioelectricity in developmental biology: new tools and recent discoveries: control of cell behavior and pattern formation by transmembrane potential gradients. BioEssays 34(3):205–217. https://doi.org/10.1002/bies.201100136
Lloyd S (2011) Quantum coherence in biological systems. J Phys Conf Ser 302:012037. https://doi.org/10.1088/1742-6596/302/1/012037
May V, Kühn O (2011) Electronic and vibrational molecular states. In: May V, Kühn O (eds) Charge and energy transfer dynamics in molecular systems. Wiley, New York. https://doi.org/10.1002/9783527633791
Movasaghi Z, Rehman S, ur Rehmann DI (2008) Fourier Transform Infrared (FTIR) spectroscopy of biological tissues. Appl Spectrosc Rev 43(2):134–179. https://doi.org/10.1080/0570492070182904
Murugan NJ, Karbowski LM, Persinger MA (2015) Cosic’s resonance model for protein sequences and photon emission differentiates lethal and non-lethal ebola strains: implications for treatment. Open J Biophys 05(01):35–43. https://doi.org/10.4236/ojbiphy.2015.51003
Nebenfuhr A, Staehelin LA (2001) Mobile factories: Golgi dynamics in plant cells. Trends Plant Sci 6(4):160–167. https://doi.org/10.1016/S1360-1385(01)01891-X
Nuccitelli R (2003) Endogenous electric fields in embryos during development, regeneration and wound healing. Radiat Prot Dosim 106(4):375–383. https://doi.org/10.1093/oxfordjournals.rpd.a006375
Pelletier J, Pelletier CC (2010) Spectroscopic theory for chemical imaging. In: Raman, infrared, and near-infrared chemical imaging. Wiley, New York. https://doi.org/10.1002/9780470768150.ch1
Pollack GH, Clegg J (2008) Unexpected linkage between unstirred layers, exclusion zones, and water. Phase Trans Cell Biol:143–152. https://doi.org/10.1007/978-1-4020-8651-9_9
Rouleau N, Dotta BT (2014) Electromagnetic fields as structure-function zeitgebers in biological systems: environmental orchestrations of morphogenesis and consciousness. Front Integr Neurosci 8:84. https://doi.org/10.3389/fnint.2014.00084
Saito K, Katada T (2015) Mechanisms for exporting large-sized cargoes from the endoplasmic reticulum. Cell Mol Life Sci 72(19):3709–3720. https://doi.org/10.1007/s00018-015-1952-9
Steiner G, Zimmerer C (2013) IV. Infrared and Raman spectra: datasheet from Landolt-Börnstein – Group VIII advanced materials and technologies Vol 6A1: “Polymer solids and polymer melts – definitions and physical properties I” in Springer materials. In: Arndt KF, Lechner MD (eds) Springer, Berlin. https://doi.org/10.1007/978-3-642-32072-9_22
Zhao Y, Zhan Q (2012) Electric fields generated by synchronized oscillations of microtubules, centrosomes and chromosomes regulate the dynamics of mitosis and meiosis. Theor Biol Med Model 9:26. https://doi.org/10.1186/1742-4682-9-26
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2019 Springer Nature Switzerland AG
About this chapter
Cite this chapter
Jaross, W. (2019). Communication of the Cell Periphery with the Golgi Apparatus: A Hypothesis. In: Kloc, M. (eds) The Golgi Apparatus and Centriole. Results and Problems in Cell Differentiation, vol 67. Springer, Cham. https://doi.org/10.1007/978-3-030-23173-6_16
Download citation
DOI: https://doi.org/10.1007/978-3-030-23173-6_16
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-030-23172-9
Online ISBN: 978-3-030-23173-6
eBook Packages: Biomedical and Life SciencesBiomedical and Life Sciences (R0)