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Home Blood Pressure Monitoring in Clinical Research

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Book cover Home Blood Pressure Monitoring

Part of the book series: Updates in Hypertension and Cardiovascular Protection ((UHCP))

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Abstract

Home blood pressure monitoring (HBPM) performed by patients is a valuable tool in the design and execution of clinical trials in hypertension. In comparison with office blood pressure measurements, HBPM provides a much larger sample of measurements within days, weeks, or months, which are obtained in the usual environment of each individual and prevent several misrepresentative phenomena, such as white-coat and masked hypertension, the placebo effect and observer error and bias. These beneficial features lead to a more accurate definition of hypertension phenotypes and to more homogenous groups selected for clinical research. In addition, HBPM may yield higher reproducibility and improved sensitivity and precision in clinical trials that are designed to investigate circadian blood pressure characteristics, such as nocturnal hypertension, blood pressure variability, as well as long-term treatment-induced changes in blood pressure and in indexes of target organ damage and cardiovascular risk.

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Author information

Authors and Affiliations

  1. Hypertension Center STRIDE-7, National and Kapodistrian University of Athens, School of Medicine, Third Department of Medicine, Sotiria Hospital, Athens, Greece

    Angeliki Ntineri & George S. Stergiou

  2. Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine (JMU), Tochigi, Japan

    Kazuomi Kario

  3. The Shanghai Institute of Hypertension, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China

    Ji-Guang Wang

  4. Calhoun Cardiology Center, University of Connecticut School of Medicine, Farmington, CT, USA

    William White

Authors
  1. Angeliki Ntineri
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  2. Kazuomi Kario
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  3. Ji-Guang Wang
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  4. William White
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  5. George S. Stergiou
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Corresponding author

Correspondence to George S. Stergiou .

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Editors and Affiliations

  1. Hypertension Center STRIDE-7, National and Kapodistrian University of Athens, School of Medicine, Third Department of Medicine, Sotiria Hospital, Athens, Greece

    George S. Stergiou

  2. Department of Medicine and Surgery, University of Milano-Bicocca, Milano, Italy, Istituto Auxologico Italiano, IRCCS, Department of Cardiovascular, Neural and Metabolic Sciences, Milano, Italy

    Gianfranco Parati

  3. University of Milano-Bicocca, Milano, Italy

    Giuseppe Mancia

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Ntineri, A., Kario, K., Wang, JG., White, W., Stergiou, G.S. (2020). Home Blood Pressure Monitoring in Clinical Research. In: Stergiou, G., Parati, G., Mancia, G. (eds) Home Blood Pressure Monitoring. Updates in Hypertension and Cardiovascular Protection. Springer, Cham. https://doi.org/10.1007/978-3-030-23065-4_10

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  • DOI: https://doi.org/10.1007/978-3-030-23065-4_10

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  • Publisher Name: Springer, Cham

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  • Online ISBN: 978-3-030-23065-4

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