Skip to main content

FLIO in Retinal Diseases

  • Chapter
  • First Online:
Fluorescence Lifetime Imaging Ophthalmoscopy
  • 366 Accesses

Abstract

FLIO lifetimes of the fundus are dependent on structural and metabolic changes within the retina. Therefore, FLIO can provide additional information about the pathophysiology of retinal changes in various retinal diseases compared to conventional imaging techniques. FLIO measurement can be used for diagnostic purposes, to identify markers for disease progression, for follow-up examinations, and also provides a promising tool for monitoring of novel therapies.

In the following chapters, FLIO characteristics in a broad range of retinal diseases is presented, and potential clinical application is summarized.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

eBook
USD 16.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 16.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 54.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Dysli C, et al. Fluorescence lifetime imaging ophthalmoscopy. Prog Retin Eye Res. 2017;60:120–43.

    Article  Google Scholar 

  2. Sauer L, et al. Fluorescence lifetime imaging ophthalmoscopy (FLIO) of macular pigment. Invest Ophthalmol Vis Sci. 2018;59(7):3094–103.

    Article  CAS  Google Scholar 

  3. Dysli C, Wolf S, Zinkernagel MS. Autofluorescence lifetimes in geographic atrophy in patients with age-related macular degeneration. Invest Ophthalmol Vis Sci. 2016;57(6):2479–87.

    Article  CAS  Google Scholar 

  4. Dysli C, et al. Fluorescence lifetimes of Drusen in age-related macular degeneration. Invest Ophthalmol Vis Sci. 2017;58(11):4856–62.

    Article  CAS  Google Scholar 

  5. Sauer L, et al. Monitoring foveal sparing in geographic atrophy with fluorescence lifetime imaging ophthalmoscopy – a novel approach. Acta Ophthalmol. 2018;96(3):257–66.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Martin Zinkernagel .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2019 Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Zinkernagel, M., Dysli, C. (2019). FLIO in Retinal Diseases. In: Zinkernagel, M., Dysli, C. (eds) Fluorescence Lifetime Imaging Ophthalmoscopy. Springer, Cham. https://doi.org/10.1007/978-3-030-22878-1_9

Download citation

  • DOI: https://doi.org/10.1007/978-3-030-22878-1_9

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-22877-4

  • Online ISBN: 978-3-030-22878-1

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics