Abstract
FLIO lifetimes of the fundus are dependent on structural and metabolic changes within the retina. Therefore, FLIO can provide additional information about the pathophysiology of retinal changes in various retinal diseases compared to conventional imaging techniques. FLIO measurement can be used for diagnostic purposes, to identify markers for disease progression, for follow-up examinations, and also provides a promising tool for monitoring of novel therapies.
In the following chapters, FLIO characteristics in a broad range of retinal diseases is presented, and potential clinical application is summarized.
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References
Dysli C, et al. Fluorescence lifetime imaging ophthalmoscopy. Prog Retin Eye Res. 2017;60:120–43.
Sauer L, et al. Fluorescence lifetime imaging ophthalmoscopy (FLIO) of macular pigment. Invest Ophthalmol Vis Sci. 2018;59(7):3094–103.
Dysli C, Wolf S, Zinkernagel MS. Autofluorescence lifetimes in geographic atrophy in patients with age-related macular degeneration. Invest Ophthalmol Vis Sci. 2016;57(6):2479–87.
Dysli C, et al. Fluorescence lifetimes of Drusen in age-related macular degeneration. Invest Ophthalmol Vis Sci. 2017;58(11):4856–62.
Sauer L, et al. Monitoring foveal sparing in geographic atrophy with fluorescence lifetime imaging ophthalmoscopy – a novel approach. Acta Ophthalmol. 2018;96(3):257–66.
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Zinkernagel, M., Dysli, C. (2019). FLIO in Retinal Diseases. In: Zinkernagel, M., Dysli, C. (eds) Fluorescence Lifetime Imaging Ophthalmoscopy. Springer, Cham. https://doi.org/10.1007/978-3-030-22878-1_9
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DOI: https://doi.org/10.1007/978-3-030-22878-1_9
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Publisher Name: Springer, Cham
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