Abstract
Left ventricular function and morphology have been shown to be important factors in clinical and pre-clinical cardiovascular disease. In this paper we used atlas-based techniques to capture the full extent of morphological changes at end-diastole, end-systole and in a coupled functional atlas for 4547 UK Biobank participants. The morphological differences between participants with risk factors for cardiovascular disease were tested using a logistic regression model. The result was compared to a model built from traditional mass and volume measures, and the strength of associations were tested using a Delong’s test. Atlas based models had stronger associations with risk factors than mass and volume parameters in most risk factors. The functional atlas showed better performance than the separate end-diastole and end-systole atlases.
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Gilbert, K. et al. (2019). End-Diastolic and End-Systolic LV Morphology in the Presence of Cardiovascular Risk Factors: A UK Biobank Study. In: Coudière, Y., Ozenne, V., Vigmond, E., Zemzemi, N. (eds) Functional Imaging and Modeling of the Heart. FIMH 2019. Lecture Notes in Computer Science(), vol 11504. Springer, Cham. https://doi.org/10.1007/978-3-030-21949-9_33
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DOI: https://doi.org/10.1007/978-3-030-21949-9_33
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