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A Pharmacokinetic and Pharmacodynamic Review

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Critical Care of Children with Heart Disease

Abstract

Important pharmacodynamic and pharmacokinetic differences in drug handling are observed in newborns, infants, and children when compared to adult patients. Therefore, knowledge of pharmacokinetic and pharmacodynamic principles in the pediatric population may better ensure safe and effective medication prescribing.

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References

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Author information

Authors and Affiliations

  1. Department of Pharmacy, Pediatric Critical Care, UPMC Children’s Hospital of Pittsburgh, Pittsburgh, PA, USA

    Carol G. Vetterly

  2. University of Pittsburgh School of Pharmacy, Pittsburgh, PA, USA

    Carol G. Vetterly

  3. University of Pittsburgh Schools of Pharmacy and Medicine and Clinical Pharmacy Specialist, Hematology-Oncology and HSCT, UPMC Children’s Hospital of Pittsburgh, Pittsburgh, PA, USA

    Denise L. Howrie

Authors
  1. Carol G. Vetterly
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  2. Denise L. Howrie
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Corresponding author

Correspondence to Carol G. Vetterly .

Editor information

Editors and Affiliations

  1. Chief, Division of Cardiac Critical Care Medicine Executive Director, Telemedicine Co-director, Children’s National Heart Institute, Professor of Pediatrics, George Washington University School of Medicine, Children’s National Health System, Washington, DC, USA

    Ricardo A. Munoz

  2. Department of Pediatric Cardiothoracic Surgery, UPMC Children’s Hospital of Pittsburgh, Pittsburgh, PA, USA

    Victor O. Morell

  3. Associate Medical Director, CHCO Heart Institute Head, Pediatric Cardiac Critical Care Program & Inpatient Services Director, Cardiac Intensive Care Unit Children’s Hospital Colorado, Tenured Professor of Pediatrics, Pediatric Cardiology and Intensive Care University of Colorado Denver, School of Medicine, Aurora, CO, USA

    Eduardo M. da Cruz

  4. Department of Pharmacy, Pediatric Critical Care, UPMC Children’s Hospital of Pittsburgh, Pittsburgh, PA, USA

    Carol G. Vetterly

  5. Department of Pediatric Cardiothoracic Surgery, UPMC – Children’s Hospital of Pittsburgh, Pittsburgh, PA, USA

    Jose Pedro da Silva

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Vetterly, C.G., Howrie, D.L. (2020). A Pharmacokinetic and Pharmacodynamic Review. In: Munoz, R., Morell, V., da Cruz, E., Vetterly, C., da Silva, J. (eds) Critical Care of Children with Heart Disease . Springer, Cham. https://doi.org/10.1007/978-3-030-21870-6_8

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  • DOI: https://doi.org/10.1007/978-3-030-21870-6_8

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-21869-0

  • Online ISBN: 978-3-030-21870-6

  • eBook Packages: MedicineMedicine (R0)

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