Skip to main content

Laser Ablation of Thyroid Cancer and Metastatic Lymph Nodes

  • Chapter
  • First Online:
Image-guided Laser Ablation
  • 511 Accesses

Abstract

Laser ablation (LA) provides us with a new effective therapy for the treatment of thyroid carcinomas and cervical lymph node metastases in the neck, thanks to its minimally invasive and high thermal energy precision, particularly for the patients with recurrent metastatic nodal disease in the neck. Although it is unlikely that LA changes the clinical course, it can be performed repeatedly as a local adjuvant therapy for recurrence of the regional disease and can become a palliative treatment in selected patients who are not eligible for surgery and/or prefer not to undergo further surgery. There are many retrospective and case-series studies that show that LA is safe and effective not just to reduce mortality.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 49.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 64.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 89.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Lim H, Devesa SS, Sosa JA, et al. Trends in thyroid cancer incidence and mortality in the United States, 1974–2013. JAMA. 2017;317:1338–48.

    Article  Google Scholar 

  2. Davies L, Welch HG. Current thyroid cancer trends in the United States. JAMA Otolaryngol Head Neck Surg. 2014;140:317–22.

    Article  Google Scholar 

  3. La Vecchia C, Malvezzi M, Bosetti C, et al. Thyroid cancer mortality and incidence: a global overview. Int J Cancer. 2015;136:2187–95.

    Article  CAS  Google Scholar 

  4. Tachimori Y, Ozawa S, Numasaki H, et al. Supraclavicular node metastasis from thoracic esophageal carcinoma: a surgical series from a Japanese multi-institutional nationwide registry of esophageal cancer. J Thorac Cardiovasc Surg. 2014;148:1224–9.

    Article  Google Scholar 

  5. Sproson EL, Herd MK, Spedding AV, Brennan PA, Puxeddu R. Treatment of breast adenocarcinoma metastasis to the neck: dedifferentiation of the tumor as suggested by hormone markers. Head Neck. 2012;34:1095–9.

    Article  Google Scholar 

  6. Willner J, Kiricuta IC, Kölbl O. Locoregional recurrence of breast cancer following mastectomy: always a fatal event? Results of univariate and multivariate analysis. Int J Radiat Oncol Biol Phys. 1997;37:853–63.

    Article  CAS  Google Scholar 

  7. Haugen BR. 2015 American Thyroid Association Management guidelines for adult patients with thyroid nodules and differentiated thyroid cancer: what is new and what has changed? Cancer-Am Cancer Soc. 2017;123:372–81.

    Google Scholar 

  8. Na DG, Lee JH, Jung SL, et al. Radiofrequency ablation of benign thyroid nodules and recurrent thyroid cancers: consensus statement and recommendations. Korean J Radiol. 2012;13:117–25.

    Article  Google Scholar 

  9. Pacella CM, Mauri G, Achille G, Barbaro D, et al. Outcomes and risk factors for complications of laser ablation for thyroid nodules: a multicenter study on 1531 patients. J Clin Endocr Metab. 2015;100:3903–10.

    Article  CAS  Google Scholar 

  10. Gharib H, Hegedüs L, Pacella CM, et al. Clinical review:nonsurgical, image-guided, minimally invasive therapy for thyroid nodules. J Clin Endocrinol Metab. 2013;98:3949–57.

    Article  CAS  Google Scholar 

  11. Yang YL, Chen CZ, Zhang XH. Microwave ablation of benign thyroid nodules. Future Oncol. 2014;10:1007–14.

    Article  CAS  Google Scholar 

  12. Baek JH, Lee JH, Sung JY, et al. Complications encountered in the treatment of benign thyroid nodules with US-guided radiofrequency ablation: a multicenter study. Radiology. 2012;262:335–42.

    Article  Google Scholar 

  13. Gharib H, Papini E, Garber JR, et al. American Association of Clinical Endocrinologists, American College of Endocrinology, and Associazione Medici Endocrinologi Medical guidelines for clinical practice for the diagnosis and management of thyroid nodules—2016 update. Endocr Pract. 2016;22:1–60.

    Article  Google Scholar 

  14. Sugitani I, Toda K, Yamada K, et al. Three distinctly different kinds of papillary thyroid microcarcinoma should be recognized: our treatment strategies and outcomes. World J Surg. 2010;34:1222–31.

    Article  Google Scholar 

  15. Ito Y, Miyauchi A, Kihara M, et al. Patient age is significantly related to the progression of papillary microcarcinoma of the thyroid under observation. Thyroid. 2014;24:27–34.

    Article  CAS  Google Scholar 

  16. Tuttle RM, Fagin JA, Minkowitz G, et al. Natural history and tumor volume kinetics of papillary thyroid cancers during active surveillance. JAMA Otolaryngol. 2017;143:1015–20.

    Google Scholar 

  17. Viola D, Materazzi G, Valerio L, et al. Prophylactic central compartment lymph node dissection in papillary thyroid carcinoma: clinical implications derived from the first prospective randomized controlled single institution study. J Clin Endocr Metab. 2015;100:1316–24.

    Article  CAS  Google Scholar 

  18. Pergolizzi S, Settineri N, Santacaterina A, et al. Ipsilateral supraclavicular lymph node metastases from breast cancer as only site of disseminated disease. Chemotherapy alone vs. induction chemotherapy to radical radiation therapy. Ann Oncol. 2001;12:1091–5.

    Article  CAS  Google Scholar 

  19. Van den Sangen MJC, Coebergh JW, et al. Detection, treatment, and outcome of isolated supraclavicular recurrence in 42 patients with invasive breast carcinoma. Cancer. 2003;98:11–7.

    Article  Google Scholar 

  20. Higuchi N, Bleier AR, Jolesz FA, et al. Magnetic resonance imaging of the acute effects of interstitial neodymium:YAG laser irradiation on tissues. Investig Radiol. 1992;27:814–21.

    Article  CAS  Google Scholar 

  21. Pacella CM, Rossi Z, Bizzarri G, et al. Ultrasound-guided percutaneous laser ablation of liver tissue in a rabbit model. Eur Radiol. 1993;3:26–32.

    Article  Google Scholar 

  22. Pacella CM, Bizzarri G, Spiezia S, et al. Thyroid tissue: US-guided percutaneous laser thermal ablation. Radiology. 2004;232:272–80.

    Article  Google Scholar 

  23. Valcavi R, Riganti F, Bertani A, et al. Percutaneous laser ablation of cold benign thyroid nodules: a 3-year follow-up study in 122 patients. Thyroid. 2010;20:1253–61.

    Article  CAS  Google Scholar 

  24. Papini E, Bizzarri G, Pacella CM. Percutaneous laser ablation of benign and malignant thyroid nodules. Curr Opin Endocrinol Diabetes Obes. 2008;15:434–9.

    Article  Google Scholar 

  25. Nixon IJ, Angelos P, Shaha AR, et al. Image-guided chemical and thermal ablations for thyroid disease: review of efficacy and complications. Head Neck. 2018;40:2103–15.

    Article  Google Scholar 

  26. Pacella CM, Bizzarri G, Guglielmi R, et al. Thyroid tissue: US-guided percutaneous interstitial laser ablation—a feasibility study. Radiology. 2000;217:673–7.

    Article  CAS  Google Scholar 

  27. Wyman A, Duffy S, Sweetland HM, et al. Preliminary evaluation of a new high-power diode laser. Lasers Surg Med. 1992;12:506–9.

    Article  CAS  Google Scholar 

  28. Tranberg KG. Percutaneous ablation of liver tumours. Best Pract Res Clin Gastroenterol. 2004;18:125–45.

    Article  Google Scholar 

  29. Pacella CM, Bizzarri G, Cecconi P, et al. Hepatocellular carcinoma: long-term results of combined treatment with laser thermal ablation and transcatheter arterial chemoembolization. Radiology. 2001;219:669–78.

    Article  CAS  Google Scholar 

  30. Kim JH, Yoo WS, Park YJ, et al. Efficacy and safety of radiofrequency ablation for treatment of locally recurrent thyroid cancers smaller than 2 cm. Radiology. 2015;276:909–18.

    Article  Google Scholar 

  31. Yue W, Wang S, Yu S, et al. Ultrasound-guided percutaneous microwave ablation of solitary T1N0M0 papillary thyroid micro-carcinoma: initial experience. Int J Hyperth. 2014;30:150–7.

    Article  Google Scholar 

  32. Papini E, Guglielmi R, Gharib H, et al. Ultrasound-guided laser ablation of incidental papillary thyroid microcarcinoma: a potential therapeutic approach in patients at surgical risk. Thyroid. 2011;21(8):917–20.

    Article  Google Scholar 

  33. Valcavi R, Piana S, Bortolan GS, et al. Ultrasound-guided percutaneous laser ablation of papillary thyroid microcarcinoma: a feasibility study on three cases with pathological and immunohistochemical evaluation. Thyroid. 2013;23(12):1578–82.

    Article  Google Scholar 

  34. Zhou W, Jiang S, Zhan W, et al. Ultrasound-guided percutaneous laser ablation of unifocal T1N0M0 papillary thyroid microcarcinoma: preliminary results. Eur Radiol. 2017;27:2934–40.

    Article  Google Scholar 

  35. Kim BM, Kim MJ, Kim EK, et al. Controlling recurrent papillary thyroid carcinoma in the neck by ultrasonography-guided percutaneous ethanol injection. Eur Radiol. 2008;18:835–42.

    Article  Google Scholar 

  36. Suh CH, Baek JH, Choi YJ, et al. Efficacy and safety of radiofrequency and ethanol ablation for treating locally recurrent thyroid cancer: a systematic review and meta-analysis. Thyroid. 2016;26:420–8.

    Article  CAS  Google Scholar 

  37. Dupuy DE, Monchik JM, Decrea C, et al. Radiofrequency ablation of regional recurrence from well-differentiated thyroid malignancy. Surgery. 2001;130:971–7.

    Article  CAS  Google Scholar 

  38. Zhou W, Zhang L, Zhan W, et al. Percutaneous laser ablation for treatment of locally recurrent papillary thyroid carcinoma <15 mm. Clin Radiol. 2016;71:1233–9.

    Article  CAS  Google Scholar 

  39. Maxon HR 3rd, Englaro EE, Thomas SR, et al. Radioiodine-131 therapy for well-differentiated thyroid cancerda quantitative radiation dosimetric approach: outcome and validation in 85 patients. J Nucl Med. 1992;33:1132e6.

    Google Scholar 

  40. Monchik JM, Donatini G, Iannuccilli J, Dupuy DE. Radiofrequency ablation and percutaneous ethanol injection treatment for recurrent local and distant well-differentiated thyroid carcinoma. Ann Surg. 2006;244:296–304.

    Article  Google Scholar 

  41. Vannucchi G, Covelli D, Perrino M, et al. Ultrasoundguided percutaneous ethanol injection in papillary thyroid cancer metastatic lymph-nodes. Endocrine. 2014;47:648–51.

    Article  CAS  Google Scholar 

  42. Zhang L, Zhou W, Zhan W. Role of ultrasound in the assessment of percutaneous laser ablation of cervical metastatic lymph nodes from thyroid carcinoma. Acta Radiol. 2018;59:434–40.

    Article  Google Scholar 

  43. Mauri G, Cova L, Ierace T, et al. Treatment of metastatic lymph nodes in the neck from papillary thyroid carcinoma with percutaneous laser ablation. Cardiovasc Intervent Radiol. 2016;39:1023–30.

    Article  Google Scholar 

  44. Gambelunghe G, Fede R, Bini V, et al. Ultrasound-guided interstitial laser ablation for thyroid nodules is effective only at high total amounts of energy: results from a three-year pilot study. Surgery. 2013;20:345–50.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Tian’an Jiang .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2020 Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Jiang, T., Solbiati, L., Zhan, W., Mauri, G. (2020). Laser Ablation of Thyroid Cancer and Metastatic Lymph Nodes. In: Pacella, C., Jiang, T., Mauri, G. (eds) Image-guided Laser Ablation. Springer, Cham. https://doi.org/10.1007/978-3-030-21748-8_8

Download citation

  • DOI: https://doi.org/10.1007/978-3-030-21748-8_8

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-21747-1

  • Online ISBN: 978-3-030-21748-8

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics