RNA Interference: A Veterinary Health Perspective
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RNA interference (RNAi) is a naturally evolved and a conserved self-defensive mechanism triggered by double-stranded RNA (dsRNA) that limits transcript levels either by suppressing transcription or activating sequence-specific degradation of RNA. RNAi protects the host from endogenous and exogenous invading nucleic acids by regulating gene expression. RNAi is used as a promising tool in functional genomics and targeting microbial infections.
RNAi is a natural mechanism of self-defense in living organisms
RNAi is used as a tool to prevent zoonotic infections and non-infectious diseases.
KeywordsRNAi RNA isoforms Virus Bacteria Vaccines Gene suppression CRISPR/Cas-9 Drosophila melanogaster
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