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Somatic Cell Nuclear Transfer

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Advances in Animal Biotechnology

Abstract

In biological system, the term “cloning” has different meanings. Animal cloning, the somatic cell nuclear transfer (SCNT) cloning, became a buzzword when Dolly, the first mammalian species was born from the nuclear transfer of fibroblasts taken from adult sheep. The technique revolutionized the field regenerative medicine, and paved way to engineer stem cells for biomedical applications. At present, a number of animal species including cloned transgenic animals are produced. There are scopes to improve the technique for its wider use for health and welfare of humans.

Highlights

  • The current nuclear transfer cloning is a more-than-two-decade-old technique that led to concept of direct reprogramming of mature cells.

  • Use of technique is advocated to create animals for experiments and biomedical testing.

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Authors and Affiliations

  1. ICAR-Indian Veterinary Research Institute, Regional Station, Palampur, India

    Birbal Singh & Gorakh Mal

  2. Department of Biotechnology, Kurukshetra University, Kurukshetra, Haryana, India

    Sanjeev K. Gautam

  3. Department of Animal Biotechnology, ICAR-National Bureau of Animal Genetic Resources, Karnal, Haryana, India

    Manishi Mukesh

Authors
  1. Birbal Singh
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  2. Gorakh Mal
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  3. Sanjeev K. Gautam
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  4. Manishi Mukesh
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Correspondence to Birbal Singh .

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Singh, B., Mal, G., Gautam, S.K., Mukesh, M. (2019). Somatic Cell Nuclear Transfer. In: Advances in Animal Biotechnology. Springer, Cham. https://doi.org/10.1007/978-3-030-21309-1_10

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