Abstract
Family history of a patient with hyper-IgM syndrome is a cornerstone of the diagnosis
Serum IgA, IgM and IgE levels might be normal, but serum IgG level is always reduced with high to normal number of B cells
Acquired forms of hyper-IgM can be seen in congenital rubella syndrome, use of antiepileptic drugs like phenytoin, and malignancies such as T cell leukemia, multiple myeloma, and lymphoma
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Çınar, S., Kara, M., Deniz, G. (2019). Gingivitis and Recurrent Tonsillitis. In: Rezaei, N. (eds) Pediatric Immunology. Springer, Cham. https://doi.org/10.1007/978-3-030-21262-9_38
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