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Heart Failure in a Patient with End-Stage Kidney Disease on Renal Replacement Therapy

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Cardiorenal Syndrome in Heart Failure

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Abstract

Cardiovascular disease (CVD) remains one of the main causes of death in patients with end-stage kidney disease on renal replacement therapy. Intermittent hemodialysis itself causes significant hemodynamic stress and vascular changes as well as a potential high-output state from arteriovenous fistula that can be linked to left ventricular hypertrophy and myocardial ischemia and stunning. Cardiovascular and metabolic changes such as fluid overload, uremia, secondary hyperparathyroidism, anemia, and dyslipidemia contribute to high CVD risks. Appropriate heart failure and coronary artery disease management (e.g. drugs and devices) as well as metabolic treatment (e.g. anemia) may attenuate disease progression, while modifications in modalities of renal replacement therapy or renal transplant may provide a more favorable cardiovascular profile.

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Authors and Affiliations

  1. Cleveland Clinic Lerner College of Medicine, Cleveland Clinic, Cleveland, OH, USA

    Shadi Ahmadmehrabi

  2. Department of Nephrology, Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH, USA

    Hernan Rincon-Choles

  3. Department of Cardiovascular Medicine Cleveland Clinic, Cleveland, OH, USA

    W. H. Wilson Tang

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  1. Shadi Ahmadmehrabi
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  2. Hernan Rincon-Choles
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  3. W. H. Wilson Tang
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Correspondence to W. H. Wilson Tang .

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Editors and Affiliations

  1. Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, OH, USA

    W. H. Wilson Tang

  2. Department of Internal Medicine, UZ Leuven, Leuven, Belgium

    Frederik H. Verbrugge

  3. Ziekenhuis Oost-Limburg, Genk University Hasselt, Genk, Belgium

    Wilfried Mullens

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Ahmadmehrabi, S., Rincon-Choles, H., Tang, W.H.W. (2020). Heart Failure in a Patient with End-Stage Kidney Disease on Renal Replacement Therapy. In: Tang, W., Verbrugge, F., Mullens, W. (eds) Cardiorenal Syndrome in Heart Failure. Springer, Cham. https://doi.org/10.1007/978-3-030-21033-5_8

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