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Cardiorenal Syndrome in Heart Failure pp 227–247Cite as

Cardiorenal Syndrome in a Patient with Mechanical Circulatory Support

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Abstract

Cardiovascular diseases are often associated with concomitant or de novo kidney disease. Renal dysfunction is common in patients with advanced heart failure. Although irreversible renal dysfunction and treatment with renal replacement therapy are considered an absolute contraindication to left ventricular assist device (LVAD) implantation as destination therapy, advanced heart failure patients with recent onset renal dysfunction should not be excluded from LVAD treatment when improvement of renal function post LVAD is anticipated. The implantation of LVADs is accompanied by short-term improvements in renal function, whereas data on long-term outcomes is ambiguous. Acute kidney injury (AKI) is not uncommon after LVAD implantation and it is accompanied by high mortality rates. Whether the type of mechanical circulatory support (MCS) device (pulsatile vs non-pulsatile) has a different effect on renal function remains unknown. The emerging role of percutaneous, short-term MCS devices for the restoration or the preservation of renal function is promising.

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Authors and Affiliations

  1. Department of Cardiovascular Medicine, Heart and Vascular Institute, Kaufman Center for Heart Failure, Cleveland Clinic, Cleveland, OH, USA

    Andrew Xanthopoulos & Randall C. Starling

  2. Department of Cardiology, University General Hospital of Larissa, Larissa, Greece

    Andrew Xanthopoulos & Filippos Triposkiadis

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  1. Andrew Xanthopoulos
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  2. Filippos Triposkiadis
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  3. Randall C. Starling
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Correspondence to Randall C. Starling .

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  1. Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, OH, USA

    W. H. Wilson Tang

  2. Department of Internal Medicine, UZ Leuven, Leuven, Belgium

    Frederik H. Verbrugge

  3. Ziekenhuis Oost-Limburg, Genk University Hasselt, Genk, Belgium

    Wilfried Mullens

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Xanthopoulos, A., Triposkiadis, F., Starling, R.C. (2020). Cardiorenal Syndrome in a Patient with Mechanical Circulatory Support. In: Tang, W., Verbrugge, F., Mullens, W. (eds) Cardiorenal Syndrome in Heart Failure. Springer, Cham. https://doi.org/10.1007/978-3-030-21033-5_16

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