Abstract
While most patients admitted with congestive heart failure have preserved blood pressure and adequate organ perfusion, an important minority present with low cardiac output and profound organ dysfunction. A careful physical examination can help detect these patients who exhibit signs of volume overload (elevated neck veins, peripheral edema) and impaired cardiac output (narrow pulse pressure, cool or cold extremities). The cold wet patient has significantly increased mortality, even during the hospitalizations because of a cascade of physiologic abnormalities which must be recognized and reversed quickly to avoid multiorgan failure. Worsening renal function is often the first marker of critical illness in the cold wet patient and is one cause of the cardiorenal syndrome. Although low cardiac output may be the cause of a minority of cases of the cardiorenal syndrome, its contribution when present must be recognized and corrected, if possible, to prevent further renal deterioration and patient demise.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
H. F. S. of America. HFSA 2010 comprehensive heart failure practice guideline. J Card Fail. 2010;16(6):e1–2.
Nohria A, et al. Clinical assessment identifies hemodynamic profiles that predict outcomes in patients admitted with heart failure. J Am Coll Cardiol. 2003;41(10):1797–804.
Fonarow GC, Adams KF, Abraham WT, Yancy CW, Boscardin WJ, S. G. for the ADHERE Scientific Advisory Committee. Risk stratification for in-hospital mortality in acutely decompensated heart failure: classification and regression tree analysis. JAMA. 2005;293(5):572–80.
Packer M. The neurohormonal hypothesis: a theory to explain the mechanism of disease progression in heart failure. J Am Coll Cardiol. 1992;20(1):248–54.
Ungar A, et al. Renal, but not systemic, hemodynamic effects of dopamine are influenced by the severity of congestive heart failure. Crit Care Med. 2004;32(5):1125–9.
Westman L, Järnberg P-O. Effects of dobutamine on haemodynamics and renal function in patients after major vascular surgery. Acta Anaesthesiol Scand. 1987;31(3):253–7.
Ljungman S, Laragh JH, Cody RJ. Role of the kidney in congestive heart failure. Drugs. 1990;39(4):10–21.
Dupont M, Mullens W, Finucan M, Taylor DO, Starling RC, Tang WHW. Determinants of dynamic changes in serum creatinine in acute decompensated heart failure: the importance of blood pressure reduction during treatment. Eur J Heart Fail. 2013;15(4):433–40.
Toma M, Starling RC. Inotropic therapy for end-stage heart failure patients. Curr Treat Options Cardiovasc Med. 2010;12(5):409–19.
Gorodeski EZ, Chu EC, Reese JR, Shishehbor MH, Hsich E, Starling RC. Prognosis on chronic dobutamine or milrinone infusions for stage D heart failure. Circ Heart Fail. 2009;2(4):320–4.
Packer M, et al. Effect of carvedilol on the morbidity of patients with severe chronic heart failure: results of the carvedilol prospective randomized cumulative survival (COPERNICUS) study. Circulation. 2002;106(17):2194–9.
Hjalmarson Å, et al. Effects of controlled-release metoprolol on total mortality, hospitalizations, and well-being in patients with heart failure: the Metoprolol CR/XL Randomized Intervention Trial in Congestive Heart Failure (MERIT-HF). JAMA. 2000;283(10):1295–302.
Beta-Blocker Evaluation of Survival Trial Investigators, Eichhorn EJ, Domanski MJ, Krause-Steinrauf H, Bristow MR, Lavori PW. A trial of the beta-blocker bucindolol in patients with advanced chronic heart failure. N Engl J Med. 2001;344(22):1659–67.
Mullens W, et al. Importance of venous congestion for worsening of renal function in advanced decompensated heart failure. J Am Coll Cardiol. 2009;53(7):589–96.
Firth JD, Raine AEG, Ledingham JGG. Raised venous pressure: a direct cause of renal sodium retention in oedema? Lancet. 1988;331(8593):1033–6.
Winton FR. The influence of venous pressure on the isolated mammalian kidney. J Physiol. 1931;72(1):49–61.
Califf RM, Bengtson JR. Cardiogenic shock. N Engl J Med. 1994;330(24):1724–30.
Gruhn N, et al. Cerebral blood flow in patients with chronic heart failure before and after heart transplantation. Stroke. 2001;32(11):2530–3.
Leier CV, Binkley PE. Parenteral inotropic support for advanced congestive heart failure. Prog Cardiovasc Dis. 1998;41(3):207–24.
Leier CVMD, Heban PTMD, Huss PRN, Bush CAMD, Lewis RPMD. Comparative systemic and regional hemodynamic effects of dopamine and dobutamine in patients with cardiomyopathic heart failure. Circulation. 1978;58(3):466–75.
Upadya S, et al. Home continuous positive inotropic infusion as a bridge to cardiac transplantation in patients with end-stage heart failure. J Heart Lung Transplant. 2004;23(4):466–72.
Kimura BJ. Point-of-care cardiac ultrasound techniques in the physical examination: better at the bedside. Heart. 2017;103(13):987–94.
Simon MA, Schnatz RG, Romeo JD, Pacella JJ. Bedside ultrasound assessment of jugular venous compliance as a potential point-of-care method to predict acute decompensated heart failure 30-day readmission. J Am Heart Assoc Cardiovasc Cerebrovasc Dis. 2018;7(15):e008184.
Garibyan VN, Amundson SA, Shaw DJ, Phan JN, Showalter BK, Kimura BJ. Lung ultrasound findings detected during inpatient echocardiography are common and associated with short- and long-term mortality. J Ultrasound Med. 2018;37(7):1641–8.
Meersch M, et al. Prevention of cardiac surgery-associated AKI by implementing the KDIGO guidelines in high risk patients identified by biomarkers: the PrevAKI randomized controlled trial. Intensive Care Med. 2017;43(11):1551–61.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2020 Springer Nature Switzerland AG
About this chapter
Cite this chapter
Christophy, A., Heywood, J.T. (2020). Low Output Heart Failure: The Cold and Wet Patient. In: Tang, W., Verbrugge, F., Mullens, W. (eds) Cardiorenal Syndrome in Heart Failure. Springer, Cham. https://doi.org/10.1007/978-3-030-21033-5_15
Download citation
DOI: https://doi.org/10.1007/978-3-030-21033-5_15
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-030-21032-8
Online ISBN: 978-3-030-21033-5
eBook Packages: MedicineMedicine (R0)